(Q51841784)

13 April 2018

title

PI-3 K/AKT and ERK signaling pathways mediate leptin-induced inhibition of PPARgamma gene expression in primary rat hepatic stellate cells. (English)

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13 April 2018

author name string

Yajun Zhou

1

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13 April 2018

Xin Jia

2

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13 April 2018

Guohua Wang

3

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13 April 2018

Xin Wang

4

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13 April 2018

Jie Liu

5

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13 April 2018

publication date

4 February 2009

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13 April 2018

Molecular and Cellular Biochemistry

published in

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13 April 2018

volume

325

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13 April 2018

issue

1-2

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13 April 2018

page(s)

131-139

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13 April 2018

The roles of leptin and adiponectin: a novel paradigm in adipocytokine regulation of liver fibrosis and stellate cell biology

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11010-009-0027-3

Leptin-induced IL-6 production is mediated by leptin receptor, insulin receptor substrate-1, phosphatidylinositol 3-kinase, Akt, NF-kappaB, and p300 pathway in microglia

21 January 2018

1 reference

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https://api.crossref.org/works/10.1007%2FS11010-009-0027-3

The role of p70S6K in hepatic stellate cell collagen gene expression and cell proliferation

21 January 2018

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12 December 2020

A novel potent antagonist of peroxisome proliferator-activated receptor gamma blocks adipocyte differentiation but does not revert the phenotype of terminally differentiated adipocytes

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12 December 2020

Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells

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12 December 2020

Positional cloning of the mouse obese gene and its human homologue

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12 December 2020

AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

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12 December 2020

Peroxisome proliferator-activated receptor gamma transcriptional regulation is involved in platelet-derived growth factor-induced proliferation of human hepatic stellate cells

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12 December 2020

The MAPK signaling cascade

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12 December 2020

Regulation of B-cell activation and differentiation by the phosphatidylinositol 3-kinase and phospholipase Cgamma pathway

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12 December 2020

Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro.

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12 December 2020

In vitro and in vivo protection of stellate cells from apoptosis by leptin

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12 December 2020

Retinol and extracellular collagen matrices modulate hepatic Ito cell collagen phenotype and cellular retinol binding protein levels

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12 December 2020

The role of focal adhesion kinase-phosphatidylinositol 3-kinase-akt signaling in hepatic stellate cell proliferation and type I collagen expression

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12 December 2020

Quantitative reverse transcription-polymerase chain reaction to study mRNA decay: comparison of endpoint and real-time methods

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12 December 2020

The biology and clinical relevance of the PTEN tumor suppressor pathway

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12 December 2020

Leptin deficiency reduces but does not eliminate the development of hepatic fibrosis in mice infected with Schistosoma mansoni

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12 December 2020

Adipogenic transcriptional regulation of hepatic stellate cells

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12 December 2020

Transdifferentiation of rat hepatic stellate cells results in leptin expression

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12 December 2020

The interruption of the PDGF and EGF signaling pathways by curcumin stimulates gene expression of PPARgamma in rat activated hepatic stellate cell in vitro

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12 December 2020

Leptin down-regulates peroxisome proliferator-activated receptor γ (PPARγ) mRNA levels in primary human monocyte-derived macrophages

1 reference

12 December 2020

Peroxisome proliferator-activated receptor gamma induces a phenotypic switch from activated to quiescent hepatic stellate cells

1 reference

12 December 2020

The antioxidant (-)-epigallocatechin-3-gallate inhibits activated hepatic stellate cell growth and suppresses acetaldehyde-induced gene expression

1 reference

12 December 2020

Ligands of peroxisome proliferator-activated receptor γ modulate profibrogenic and proinflammatory actions in hepatic stellate cells

1 reference

12 December 2020

Leptin enhances alpha1(I) collagen gene expression in LX-2 human hepatic stellate cells through JAK-mediated H2O2-dependent MAPK pathways

1 reference

12 December 2020

Leptin induces mitogen-activated protein kinase-dependent proliferation of C3H10T1/2 cells

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12 December 2020

Leptin is essential for the hepatic fibrogenic response to chronic liver injury

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12 December 2020

A peroxisome-proliferator activated receptor-gamma ligand could regulate the expression of leptin receptor on human hepatic stellate cells

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12 December 2020

Expression of cyclins D1, D2 and E correlates with proliferation of rat stellate cells in culture

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12 December 2020

Leptin is required for fibrogenic responses induced by thioacetamide in the murine liver

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12 December 2020

Upregulation of proinflammatory and proangiogenic cytokines by leptin in human hepatic stellate cells.

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12 December 2020

Leptin augments inflammatory and profibrogenic responses in the murine liver induced by hepatotoxic chemicals

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12 December 2020

PDGF and signal transduction in hepatic stellate cells

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12 December 2020

The organization, promoter analysis, and expression of the human PPARgamma gene

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12 December 2020

Leptin receptor-mediated signaling regulates hepatic fibrogenesis and remodeling of extracellular matrix in the rat.

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12 December 2020

The forkhead transcription factor FoxO1 regulates proliferation and transdifferentiation of hepatic stellate cells

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12 December 2020

Leptin as a novel profibrogenic cytokine in hepatic stellate cells: mitogenesis and inhibition of apoptosis mediated by extracellular regulated kinase (Erk) and Akt phosphorylation

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12 December 2020

The phosphoinositide 3-kinase pathway

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12 December 2020

Serum leptin levels in patients with nonalcoholic steatohepatitis.

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12 December 2020

Leptin effect on endothelial nitric oxide is mediated through Akt-endothelial nitric oxide synthase phosphorylation pathway.

1 reference

12 December 2020

Peroxisome proliferator-activated receptors and hepatic stellate cell activation

1 reference

12 December 2020

Leptin in hepatic fibrosis: evidence for increased collagen production in stellate cells and lean littermates of ob/ob mice

1 reference

12 December 2020

10.1007/S11010-009-0027-3

Identifiers

DOI

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13 April 2018

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13 April 2018