(Q51842650)

13 April 2018

title

Topical treatment targeting sphingosine-1-phosphate and sphingosine lyase abrogates experimental allergic rhinitis in a murine model. (English)

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13 April 2018

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A Kleinjan

1

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M van Nimwegen

2

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K Leman

3

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H C Hoogsteden

4

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B N Lambrecht

5

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publication date

18 December 2012

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published in

Allergy

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volume

68

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issue

2

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page(s)

204-212

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Transepithelial migration of activated eosinophils induces a decrease of E-cadherin expression in cultured human nasal epithelial cells

cites work

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In vivo depletion of lung CD11c+ dendritic cells during allergen challenge abrogates the characteristic features of asthma

21 January 2018

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Modulating tone: the overture of S1P receptor immunotherapeutics

21 January 2018

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Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function

21 January 2018

1 reference

Inhibition of Th1- and Th2-mediated airway inflammation by the sphingosine 1-phosphate receptor agonist FTY720.

21 January 2018

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Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients

21 January 2018

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FTY720 ameliorates Th1-mediated colitis in mice by directly affecting the functional activity of CD4+CD25+ regulatory T cells.

21 January 2018

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A functional role for CCR6 on proallergic T cells in the gastrointestinal tract

21 January 2018

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The role of sphingosine kinase in a murine model of allergic asthma

21 January 2018

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Anti-inflammatory effects of sphingosine kinase modulation in inflammatory arthritis

21 January 2018

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Treatment with FTY720 during the induction or effector phase suppresses the development of experimental allergic conjunctivitis in mice

21 January 2018

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Regulation of the roles of sphingosine 1-phosphate and its type 1 G protein-coupled receptor in T cell immunity and autoimmunity

21 January 2018

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Anti-inflammatory effects of FTY720 against viral-induced immunopathology: role of drug-induced conversion of T cells to become Foxp3+ regulators

21 January 2018

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Dynamics of mast cells in the nasal mucosa of patients with allergic rhinitis and non-allergic controls: a biopsy study

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/ALL.12082

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13 April 2018

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13 April 2018