(Q51892667)

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The Pou5f1/Pou3f-dependent but SoxB-independent regulation of conserved enhancer N2 initiates Sox2 expression during epiblast to neural plate stages in vertebrates.

scientific article published on 23 December 2010

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21185279%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

The Pou5f1/Pou3f-dependent but SoxB-independent regulation of conserved enhancer N2 initiates Sox2 expression during epiblast to neural plate stages in vertebrates (English)

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18 January 2020

Wolfgang Driever

5

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18 January 2020

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18 January 2020

Daria Onichtchouk

3

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18 January 2020

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Makiko Iwafuchi-Doi

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18 January 2020

Yuzo Yoshida

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18 January 2020

Manuel Leichsenring

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18 January 2020

Tatsuya Takemoto

6

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18 January 2020

Masanori Uchikawa

7

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18 January 2020

Hisato Kondoh

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18 January 2020

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23 December 2010

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18 January 2020

Developmental Biology

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18 January 2020

352

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18 January 2020

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18 January 2020

354-366

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18 January 2020

Multipotent cell lineages in early mouse development depend on SOX2 function

1 reference

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Conserved POU binding DNA sites in the Sox2 upstream enhancer regulate gene expression in embryonic and neural stem cells.

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Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain

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SOX2 functions to maintain neural progenitor identity

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Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst

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Combinatorial expression of zebrafish Brn-1- and Brn-2-related POU genes in the embryonic brain, pronephric primordium, and pharyngeal arches.

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7 January 2021

PAX6 and SOX2-dependent regulation of the Sox2 enhancer N-3 involved in embryonic visual system development

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Overlapping positive and negative regulatory elements determine lens-specific activity of the delta 1-crystallin enhancer

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Evolution of non-coding regulatory sequences involved in the developmental process: reflection of differential employment of paralogous genes as highlighted by Sox2 and group B1 Sox genes

1 reference

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7 January 2021

SOX-partner code for cell specification: Regulatory target selection and underlying molecular mechanisms

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7 January 2021

Zebrafish pou5f1/pou2, homolog of mammalian Oct4, functions in the endoderm specification cascade

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7 January 2021

Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells.

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7 January 2021

The octamer binding factor Oct6: cDNA cloning and expression in early embryonic cells

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7 January 2021

The Sox2 regulatory region 2 functions as a neural stem cell-specific enhancer in the telencephalon

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7 January 2021

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

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7 January 2021

How is pluripotency determined and maintained?

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7 January 2021

Comparative genomic and expression analysis of group B1 sox genes in zebrafish indicates their diversification during vertebrate evolution

1 reference

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7 January 2021

B1 SOX coordinate cell specification with patterning and morphogenesis in the early zebrafish embryo

1 reference

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7 January 2021

Zebrafish Pou5f1-dependent transcriptional networks in temporal control of early development

1 reference

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7 January 2021

A mechanism regulating the onset of Sox2 expression in the embryonic neural plate

1 reference

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7 January 2021

The POU domain protein spg (pou2/Oct4) is essential for endoderm formation in cooperation with the HMG domain protein casanova

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7 January 2021

A transgenic mouse line that retains Cre recombinase activity in mature oocytes irrespective of the cre transgene transmission

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Enhancer analysis of the mouse HNF-3 beta gene: regulatory elements for node/notochord and floor plate are independent and consist of multiple sub-elements

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7 January 2021

Development and survival of the endocrine hypothalamus and posterior pituitary gland requires the neuronal POU domain factor Brn-2

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7 January 2021

Capturing pluripotency

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Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

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A novel POU domain gene, zebrafish pou2: expression and roles of two alternatively spliced twin products in early development

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Convergence of Wnt and FGF signals in the genesis of posterior neural plate through activation of the Sox2 enhancer N-1.

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Interplay of SOX and POU factors in regulation of the Nestin gene in neural primordial cells

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SOX2 is a dose-dependent regulator of retinal neural progenitor competence

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New cell lines from mouse epiblast share defining features with human embryonic stem cells

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Identification of Sox-2 regulatory region which is under the control of Oct-3/4-Sox-2 complex

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Enhancer analysis by chicken embryo electroporation with aid of genome comparison

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Two distinct subgroups of Group B Sox genes for transcriptional activators and repressors: their expression during embryonic organogenesis of the chicken

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Functional analysis of chicken Sox2 enhancers highlights an array of diverse regulatory elements that are conserved in mammals

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Isolation, characterization, and differential expression of the murine Sox-2 promoter

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Comparative expression of the mouse Sox1, Sox2 and Sox3 genes from pre-gastrulation to early somite stages.

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Oct-3/4 dose dependently regulates specification of embryonic stem cells toward a cardiac lineage and early heart development.

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The restricted expression pattern of the POU factor Oct-6 during early development of the mouse nervous system.

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