(Q51919751)

English

Clinical involvement of catechol-O-methyltransferase polymorphisms in schizophrenia spectrum disorders: influence on the severity of psychotic symptoms and on the response to neuroleptic treatment.

scientific article published on 13 March 2007

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17363961%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Clinical involvement of catechol-O-methyltransferase polymorphisms in schizophrenia spectrum disorders: influence on the severity of psychotic symptoms and on the response to neuroleptic treatment (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17363961%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

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27 December 2019

Patricio Molero

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27 December 2019

Ana Patiño-García

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27 December 2019

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Zalacain M

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27 December 2019

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13 March 2007

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27 December 2019

The Pharmacogenomics Journal

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27 December 2019

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27 December 2019

6

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27 December 2019

418-426

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27 December 2019

https://scigraph.springernature.com/pub.10.1038/sj.tpj.6500441

0 references

Genetic basis of schizophrenia.

1 reference

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Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies

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Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia

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Dopamine in schizophrenia: a review and reconceptualization

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Catechol-o-methyltransferase, cognition, and psychosis: Val158Met and beyond

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Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia

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Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence

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Association between a functional catechol O-methyltransferase gene polymorphism and schizophrenia: meta-analysis of case-control and family-based studies

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21 January 2018

Lack of association of the COMT (Val158/108 Met) gene and schizophrenia: a meta-analysis of case-control studies

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21 January 2018

Catechol-O-methyltransferase gene Val/Met functional polymorphism and risk of schizophrenia: a large-scale association study plus meta-analysis

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21 January 2018

Catechol-O-methyltransferase and monoamine oxidase A genotypes and drug response to conventional neuroleptics in schizophrenia

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21 January 2018

Effect of DRD2, 5-HT2A, and COMT genes on antipsychotic response to risperidone.

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21 January 2018

Neurocognitive correlates of the COMT Val(158)Met polymorphism in chronic schizophrenia.

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21 January 2018

New evidence of association between COMT gene and prefrontal neurocognitive function in healthy individuals from sibling pairs discordant for psychosis

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21 January 2018

Effects of a functional COMT polymorphism on prefrontal cognitive function in patients with 22q11.2 deletion syndrome

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21 January 2018

Catechol O-methyltransferase Val158Met polymorphism in schizophrenia: differential effects of Val and Met alleles on cognitive stability and flexibility.

1 reference

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21 January 2018

Catechol-o-methyltransferase inhibition improves set-shifting performance and elevates stimulated dopamine release in the rat prefrontal cortex

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21 January 2018

Physiological dysfunction of the dorsolateral prefrontal cortex in schizophrenia revisited.

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Functional hypofrontality and working memory dysfunction in schizophrenia

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Genes, dopamine and cortical signal-to-noise ratio in schizophrenia

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Stress activation of glutamate neurotransmission in the prefrontal cortex: implications for dopamine-associated psychiatric disorders

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Human catechol O-methyltransferase genetic variation: gene resequencing and functional characterization of variant allozymes

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A highly significant association between a COMT haplotype and schizophrenia.

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COMT haplotypes suggest P2 promoter region relevance for schizophrenia.

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Prefrontal neurons and the genetics of schizophrenia

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Abnormal fMRI response of the dorsolateral prefrontal cortex in cognitively intact siblings of patients with schizophrenia

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Genetic and neurochemical modulation of prefrontal cognitive functions in children.

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Executive subprocesses in working memory: relationship to catechol-O-methyltransferase Val158Met genotype and schizophrenia

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Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles.

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Genotype determining low catechol-O-methyltransferase activity as a risk factor for obsessive-compulsive disorder

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Interaction of COMT (Val(108/158)Met) genotype and olanzapine treatment on prefrontal cortical function in patients with schizophrenia.

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Catechol-O-methyltransferase val108/158met genotype predicts working memory response to antipsychotic medications

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Evaluating associations of haplotypes with traits

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Pedigree disequilibrium tests for multilocus haplotypes.

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Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders.

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