(Q51926763)

17 April 2018

title

RNA aptamers interfering with nucleophosmin oligomerization induce apoptosis of cancer cells. (English)

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17 April 2018

author name string

Y Jian

1

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17 April 2018

Z Gao

2

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17 April 2018

J Sun

3

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17 April 2018

Q Shen

4

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17 April 2018

F Feng

5

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17 April 2018

Y Jing

6

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17 April 2018

C Yang

7

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17 April 2018

language of work or name

English

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publication date

7 September 2009

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17 April 2018

published in

Oncogene

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17 April 2018

volume

28

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17 April 2018

issue

47

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17 April 2018

page(s)

4201-4211

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17 April 2018

https://scigraph.springernature.com/pub.10.1038/onc.2009.275

exact match

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cites work

Regulation of p14ARF through subnuclear compartmentalization

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Nucleophosmin/B23, a nuclear PI(3,4,5)P(3) receptor, mediates the antiapoptotic actions of NGF by inhibiting CAD

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Pegaptanib sodium for the treatment of age-related macular degeneration

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Major nucleolar proteins shuttle between nucleus and cytoplasm

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The N-terminal half of NPM dissociates from nucleoli of HeLa cells after anticancer drug treatments

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Aptamer mediated siRNA delivery

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Nucleophosmin is required for DNA integrity and p19Arf protein stability

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Nucleophosmin regulates the stability and transcriptional activity of p53

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Essential role of the B23/NPM core domain in regulating ARF binding and B23 stability

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Expression of small, therapeutic RNAs in human cell nuclei.

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Role of nucleophosmin in embryonic development and tumorigenesis

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31 March 2020

Nucleophosmin and cancer

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Discovery and development of anticancer aptamers

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Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation.

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Nucleophosmin (B23) targets ARF to nucleoli and inhibits its function

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Release of nucleophosmin from the nucleus: Involvement in aloe-emodin-induced human lung non small carcinoma cell apoptosis

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Nanotechnology and aptamers: applications in drug delivery

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Nucleophosmin sets a threshold for p53 response to UV radiation

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Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras

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The structure and function of Xenopus NO38-core, a histone chaperone in the nucleolus

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Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication

31 March 2020

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NSC348884, a nucleophosmin inhibitor disrupts oligomer formation and induces apoptosis in human cancer cells.

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Preferential cleavage in pre-ribosomal RNA byprotein B23 endoribonuclease

31 March 2020

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Interaction of nucleolar protein B23 with peptides related to nuclear localization signals

31 March 2020

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Identification of nucleolin and nucleophosmin as genotoxic stress-responsive RNA-binding proteins

31 March 2020

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RNA aptamers targeting the cell death inhibitor CED-9 induce cell killing in Caenorhabditis elegans

31 March 2020

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Mfold web server for nucleic acid folding and hybridization prediction

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/ONC.2009.275

1 reference

17 April 2018

PubMed ID

19734942

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17 April 2018