(Q51951782)

18 April 2018

title

Liver-specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice. (English)

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18 April 2018

author

Pawel K Mazur

3

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Freddy Radtke

7

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author name string

Fabian Geisler

1

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18 April 2018

Florian Nagl

2

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Marcel Lee

4

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18 April 2018

Ursula Zimber-Strobl

5

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Lothar J Strobl

6

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Roland M Schmid

8

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18 April 2018

Jens T Siveke

9

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language of work or name

English

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publication date

1 August 2008

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18 April 2018

published in

Hepatology

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18 April 2018

volume

48

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issue

2

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18 April 2018

page(s)

607-616

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Development of the intrahepatic biliary tree

cites work

1 reference

7 January 2021

Development and differentiation of bile ducts in the mammalian liver

1 reference

7 January 2021

The cholangiopathies: disorders of biliary epithelia

1 reference

7 January 2021

Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1

1 reference

7 January 2021

Mutations in the human Jagged1 gene are responsible for Alagille syndrome

1 reference

7 January 2021

Features of Alagille syndrome in 92 patients: frequency and relation to prognosis

1 reference

7 January 2021

Syndromatic paucity of interlobular bile ducts: hepatic histopathology of the early and endstage liver

1 reference

7 January 2021

Proliferation to paucity: evolution of bile duct abnormalities in a case of Alagille syndrome

1 reference

7 January 2021

Notch signaling in development and disease

1 reference

7 January 2021

Notch receptor expression in adult human liver: a possible role in bile duct formation and hepatic neovascularization

1 reference

7 January 2021

Inducible inactivation of Notch1 causes nodular regenerative hyperplasia in mice.

1 reference

7 January 2021

The role of notch signaling in the development of intrahepatic bile ducts

1 reference

7 January 2021

Bile duct proliferation in liver-specific Jag1 conditional knockout mice: effects of gene dosage.

1 reference

7 January 2021

Preferential differentiation of the bile ducts along the portal vein in the development of mouse liver

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7 January 2021

Deficient T cell fate specification in mice with an induced inactivation of Notch1.

1 reference

7 January 2021

Hierarchy of Notch-Delta interactions promoting T cell lineage commitment and maturation

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7 January 2021

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

1 reference

7 January 2021

Generalized lacZ expression with the ROSA26 Cre reporter strain

1 reference

7 January 2021

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear

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7 January 2021

Genetic inactivation of RelA/p65 sensitizes adult mouse hepatocytes to TNF-induced apoptosis in vivo and in vitro.

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7 January 2021

Concomitant pancreatic activation of Kras(G12D) and Tgfa results in cystic papillary neoplasms reminiscent of human IPMN.

1 reference

7 January 2021

Notch1 is essential for postimplantation development in mice.

1 reference

7 January 2021

Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice

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7 January 2021

Beta cells occur naturally in extrahepatic bile ducts of mice.

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7 January 2021

Transient expression of bile-duct-specific cytokeratin in fetal mouse hepatocytes

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7 January 2021

DNA excision in liver by an albumin-Cre transgene occurs progressively with age

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7 January 2021

Another Notch to be added to the list of hepatocellular growth regulatory factors?

1 reference

7 January 2021

Nomenclature of the finer branches of the biliary tree: canals, ductules, and ductular reactions in human livers

1 reference

7 January 2021

Activation of stem cells in hepatic diseases.

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7 January 2021

The origin and liver repopulating capacity of murine oval cells

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7 January 2021

Inducible gene targeting in mice

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7 January 2021

Human Jagged 1 mutants cause liver defect in Alagille syndrome by overexpression of hepatocyte growth factor.

1 reference

7 January 2021

Peripheral bile duct paucity and cholestasis in the liver of a patient with Alagille syndrome: further evidence supporting a lack of postnatal bile duct branching and elongation.

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7 January 2021

Analysis of liver repair mechanisms in Alagille syndrome and biliary atresia reveals a role for notch signaling.

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7 January 2021

NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signaling pathway

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7 January 2021

Notch signaling controls hepatoblast differentiation by altering the expression of liver-enriched transcription factors

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7 January 2021

Suppression of C/EBPalpha expression in periportal hepatoblasts may stimulate biliary cell differentiation through increased Hnf6 and Hnf1b expression

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7 January 2021

Identifiers

DOI

10.1002/HEP.22381

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18 April 2018

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18 April 2018