(Q51951890)

18 April 2018

4 references

22 June 2019

10 October 2019

7 November 2019

26 August 2020

The expanding role for retinoid signaling in heart development. (English)

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18 April 2018

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10 October 2019

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7 November 2019

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26 August 2020

Loretta L Hoover

1

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18 April 2018

Elizabeth G Burton

series ordinal

2

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18 April 2018

Bonnie A Brooks

series ordinal

3

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18 April 2018

Steven W Kubalak

series ordinal

4

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18 April 2018

language of work or name

English

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publication date

25 February 2008

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18 April 2018

The Scientific World Journal

22 June 2019

10 October 2019

7 November 2019

26 August 2020

5 references

18 April 2018

22 June 2019

10 October 2019

7 November 2019

26 August 2020

8

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18 April 2018

page(s)

194-211

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18 April 2018

Creative Commons Attribution 3.0 Unported

copyright license

4 references

22 June 2019

10 October 2019

7 November 2019

PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling

26 August 2020

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1 reference

12 December 2020

Contribution of cellular retinol-binding protein type 1 to retinol metabolism during mouse development

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12 December 2020

Expression of retinol binding protein and transthyretin during early embryogenesis

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12 December 2020

Cellular transport and metabolism of vitamin A: roles of the cellular retinoid-binding proteins.

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12 December 2020

Erythropoietin and retinoic acid, secreted from the epicardium, are required for cardiac myocyte proliferation

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12 December 2020

Ablation of the secondary heart field leads to tetralogy of Fallot and pulmonary atresia.

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12 December 2020

Effects of retinoid deficiency on the development of the heart and vascular system of the quail embryo

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12 December 2020

Ligand binding and structural analysis of a human putative cellular retinol-binding protein

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12 December 2020

Differential distribution of retinoic acid synthesis in the chicken embryo as determined by immunolocalization of the retinoic acid synthetic enzyme, RALDH-2.

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12 December 2020

The steroid and thyroid hormone receptor superfamily

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12 December 2020

Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas

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12 December 2020

Characterization of three RXR genes that mediate the action of 9-cis retinoic acid

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12 December 2020

The identification of a 9-cis retinol dehydrogenase in the mouse embryo reveals a pathway for synthesis of 9-cis retinoic acid.

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12 December 2020

New roles for systemic retinoids.

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12 December 2020

Effects of vitamin A on endocardial cushion development in the mouse heart

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12 December 2020

Beta-catenin is required for endothelial-mesenchymal transformation during heart cushion development in the mouse

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12 December 2020

Evaluating the role of Wnt signal transduction in promoting the development of the heart.

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12 December 2020

Initial retinoid requirement for early avian development coincides with retinoid receptor coexpression in the precardiac fields and induction of normal cardiovascular development

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12 December 2020

Epicardium-derived cells in cardiogenesis and cardiac regeneration

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12 December 2020

Retinoic acid directs cardiac laterality and the expression of early markers of precardiac asymmetry

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12 December 2020

Effects of excess vitamin A on development of cranial neural crest-derived structures: a neonatal and embryologic study

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12 December 2020

The epicardium and epicardially derived cells (EPDCs) as cardiac stem cells

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12 December 2020

Convergent proliferative response and divergent morphogenic pathways induced by epicardial and endocardial signaling in fetal heart development

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12 December 2020

Neural crest cells contribute to normal aorticopulmonary septation

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12 December 2020

Endogenous retinoids in the early avian embryo

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12 December 2020

Levels of phospho-Smad2/3 are sensors of the interplay between effects of TGF-beta and retinoic acid on monocytic and granulocytic differentiation of HL-60 cells

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12 December 2020

Retinaldehyde dehydrogenase 2 (RALDH2)- independent patterns of retinoic acid synthesis in the mouse embryo

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12 December 2020

Cre-constructing the heart

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12 December 2020

Expression of the atrial-specific myosin heavy chain AMHC1 and the establishment of anteroposterior polarity in the developing chicken heart

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12 December 2020

A role for GATA-4/5/6 in the regulation of Nkx2.5 expression with implications for patterning of the precardiac field.

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12 December 2020

Analysis of the proepicardium-epicardium transition during the malformation of the RXRalpha-/- epicardium

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12 December 2020

Retinoic acid signaling restricts the cardiac progenitor pool

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12 December 2020

Retinoid X receptor alpha represses GATA-4-mediated transcription via a retinoid-dependent interaction with the cardiac-enriched repressor FOG-2.

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12 December 2020

Endogenous distribution of retinoids during normal development and teratogenesis in the mouse embryo.

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12 December 2020

Isotretinoin and pregnancy

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12 December 2020

Multiple modes of repression by the Smad transcriptional corepressor TGIF

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12 December 2020

Epicardium is required for the full rate of myocyte proliferation and levels of expression of myocyte mitogenic factors FGF2 and its receptor, FGFR-1, but not for transmural myocardial patterning in the embryonic chick heart.

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12 December 2020

Eukaryotic aldehyde dehydrogenase (ALDH) genes: human polymorphisms, and recommended nomenclature based on divergent evolution and chromosomal mapping

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12 December 2020

Targeted disruption of the murine VCAM1 gene: essential role of VCAM-1 in chorioallantoic fusion and placentation

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12 December 2020

Conotruncal myocardium arises from a secondary heart field

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12 December 2020

The biological activity of retinoic acid in the domestic fowl and the effects of vitamin A deficiency on the chick embryo

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12 December 2020

Retinoids in embryonal development

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12 December 2020

Adenomatous polyposis coli (APC)-independent regulation of beta-catenin degradation via a retinoid X receptor-mediated pathway

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12 December 2020

A Wnt- and beta -catenin-dependent pathway for mammalian cardiac myogenesis

1 reference

12 December 2020

Cellular retinoic acid-binding protein II: a coactivator of the transactivation by the retinoic acid receptor complex RAR.RXR.

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12 December 2020

Retinoic acid regulation of the somitogenesis clock

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12 December 2020

Mouse Wnt receptor gene Fzd5 is essential for yolk sac and placental angiogenesis

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12 December 2020

Epicardial induction of fetal cardiomyocyte proliferation via a retinoic acid-inducible trophic factor

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12 December 2020

A mechanism for mutational inactivation of the homeodomain protein TGIF in holoprosencephaly

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12 December 2020

Energy deprivation and a deficiency in downstream metabolic target genes during the onset of embryonic heart failure in RXRalpha-/- embryos.

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12 December 2020

Defective development of the embryonic and extraembryonic circulatory systems in vascular cell adhesion molecule (VCAM-1) deficient mice

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12 December 2020

The control of morphogen signalling: regulation of the synthesis and catabolism of retinoic acid in the developing embryo

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12 December 2020

Regulation of retinal dehydrogenases and retinoic acid synthesis by cholesterol metabolites

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12 December 2020

Wnt signal transduction and the formation of the myocardium

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12 December 2020

The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm

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12 December 2020

Embryonic retinoic acid synthesis is essential for heart morphogenesis in the mouse

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12 December 2020

Expression of a retinoic acid response element-hsplacZ transgene defines specific domains of transcriptional activity during mouse embryogenesis

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12 December 2020

Altered vitamin A homeostasis and increased size and adiposity in the rdh1-null mouse.

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12 December 2020

Families of retinoid dehydrogenases regulating vitamin A function: production of visual pigment and retinoic acid

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12 December 2020

Restricted expression and retinoic acid-induced downregulation of the retinaldehyde dehydrogenase type 2 (RALDH-2) gene during mouse development.

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12 December 2020

Normal fate and altered function of the cardiac neural crest cell lineage in retinoic acid receptor mutant embryos

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12 December 2020

Experimental studies on the spatiotemporal expression of WT1 and RALDH2 in the embryonic avian heart: a model for the regulation of myocardial and valvuloseptal development by epicardially derived cells (EPDCs).

1 reference

12 December 2020

Bexarotene: a clinical review

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12 December 2020

Origin, fate, and function of epicardium-derived cells (EPDCs) in normal and abnormal cardiac development.

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12 December 2020

Three-amino acid extension loop homeodomain proteins Meis2 and TGIF differentially regulate transcription

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12 December 2020

Compartment-selective sensitivity of cardiovascular morphogenesis to combinations of retinoic acid receptor gene mutations

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12 December 2020

An analysis of the syndrome of malformations induced by maternal vitamin A deficiency. Effects of restoration of vitamin A at various times during gestation

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12 December 2020

Retinoid X receptor regulates Nur77/TR3-dependent apoptosis [corrected] by modulating its nuclear export and mitochondrial targeting

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12 December 2020

Induction of normal cardiovascular development in the vitamin A-deprived quail embryo by natural retinoids

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12 December 2020

Local sources of retinoic acid coincide with retinoid-mediated transgene activity during embryonic development

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12 December 2020

Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart

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12 December 2020

Contribution of retinoic acid receptor beta isoforms to the formation of the conotruncal septum of the embryonic heart

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12 December 2020

Increased fibronectin deposition in embryonic hearts of retinol-binding protein-null mice

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12 December 2020

Acidic and basic fibroblast growth factors in adult rat heart myocytes. Localization, regulation in culture, and effects on DNA synthesis

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12 December 2020

Endocardial and epicardial derived FGF signals regulate myocardial proliferation and differentiation in vivo

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12 December 2020

The oxidizing enzyme CYP26a1 tightly regulates the availability of retinoic acid in the gastrulating mouse embryo to ensure proper head development and vasculogenesis

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12 December 2020

Developmental expression of murine retinoid X receptor (RXR) genes.

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12 December 2020

The role of Wnt signalling in cardiac development and tissue remodelling in the mature heart

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12 December 2020

Transgenic indicator mice for studying activated retinoic acid receptors during development

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12 December 2020

Developmental analysis of the retinoic acid-inducible RAR-beta 2 promoter in transgenic animals

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12 December 2020

The cellular retinoic acid binding proteins.

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12 December 2020

RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis.

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12 December 2020

c-Jun interacts with the corepressor TG-interacting factor (TGIF) to suppress Smad2 transcriptional activity

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12 December 2020

High and low molecular weight fibroblast growth factor-2 increase proliferation of neonatal rat cardiac myocytes but have differential effects on binucleation and nuclear morphology. Evidence for both paracrine and intracrine actions of [...]

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12 December 2020

Vitamin A deficiency and mutations of RXRalpha, RXRbeta and RARalpha lead to early differentiation of embryonic ventricular cardiomyocytes

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12 December 2020

The outflow tract of the heart is recruited from a novel heart-forming field

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12 December 2020

Interactions between retinoids and TGF beta s in mouse morphogenesis

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12 December 2020

Is 9-cis-retinoic acid the endogenous ligand for the retinoic acid-X receptor?

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12 December 2020

RXR alpha deficiency confers genetic susceptibility for aortic sac, conotruncal, atrioventricular cushion, and ventricular muscle defects in mice.

1 reference

12 December 2020

Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids

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12 December 2020

Selective regulation of cardiomyocyte gene expression and cardiac morphogenesis by retinoic acid

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12 December 2020

Inhibition of Tgf beta signaling by endogenous retinoic acid is essential for primary lung bud induction.

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12 December 2020

The Smad transcriptional corepressor TGIF recruits mSin3

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12 December 2020

Retinoic acid receptors interfere with the TGF-beta/Smad signaling pathway in a ligand-specific manner.

1 reference

12 December 2020

Retinoid receptors and vitamin A deficiency: differential patterns of transcription during early avian development and the rapid induction of RARs by retinoic acid

1 reference

12 December 2020

Ventricular muscle-restricted targeting of the RXRalpha gene reveals a non-cell-autonomous requirement in cardiac chamber morphogenesis

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12 December 2020

Retinoic acid-induced developmental defects are mediated by RARbeta/RXR heterodimers in the pharyngeal endoderm.

1 reference

12 December 2020

Retinoic acid receptors and cellular retinoid binding proteins. II. Their differential pattern of transcription during early morphogenesis in mouse embryos

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12 December 2020

Increased susceptibility to retinoid-induced teratogenesis in TGF-beta2 knockout mice

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12 December 2020

A membrane receptor for retinol binding protein mediates cellular uptake of vitamin A

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12 December 2020

Specific spatial and temporal distribution of retinoic acid receptor gamma transcripts during mouse embryogenesis

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12 December 2020

Sequential programs of retinoic acid synthesis in the myocardial and epicardial layers of the developing avian heart.

1 reference

12 December 2020

The retinoic acid-inactivating enzyme CYP26 is essential for establishing an uneven distribution of retinoic acid along the anterio-posterior axis within the mouse embryo

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12 December 2020

Function of RARgamma and RARalpha2 at the initiation of retinoid signaling is essential for avian embryo survival and for distinct events in cardiac morphogenesis

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12 December 2020

Positive and negative regulation of epicardial-mesenchymal transformation during avian heart development

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12 December 2020

Interaction of nuclear receptors with the Wnt/beta-catenin/Tcf signaling axis: Wnt you like to know?

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12 December 2020

Epicardial retinoid X receptor alpha is required for myocardial growth and coronary artery formation

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12 December 2020

Retinoic acid signaling is essential for formation of the heart tube in Xenopus

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12 December 2020

Differential regulation of the expression of transforming growth factor-beta mRNAs by growth factors and retinoic acid in chicken embryo chondrocytes, myocytes, and fibroblasts

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12 December 2020

Aortic-arch and cardiac anomalies in the offspring of vitamin A deficient rats

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12 December 2020

RALDH-independent generation of retinoic acid during vertebrate embryogenesis by CYP1B1.

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12 December 2020

Decreased embryonic retinoic acid synthesis results in a DiGeorge syndrome phenotype in newborn mice

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12 December 2020

Signaling hierarchy downstream of retinoic acid that independently regulates vascular remodeling and endothelial cell proliferation

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12 December 2020

Chemopreventive n-3 fatty acids activate RXRalpha in colonocytes

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12 December 2020

Regulation of transforming growth factor-beta subtypes by members of the steroid hormone superfamily

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12 December 2020

Distribution of fibronectin, type I collagen, type IV collagen, and laminin in the cardiac jelly of the mouse embryonic heart with retinoic acid-induced complete transposition of the great arteries

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12 December 2020

Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination

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12 December 2020

Compound mutants for retinoic acid receptor (RAR) beta and RAR alpha 1 reveal developmental functions for multiple RAR beta isoforms.

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12 December 2020

Dynamic patterns of retinoic acid synthesis and response in the developing mammalian heart

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12 December 2020

Mutations in STRA6 cause a broad spectrum of malformations including anophthalmia, congenital heart defects, diaphragmatic hernia, alveolar capillary dysplasia, lung hypoplasia, and mental retardation

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12 December 2020

Genetic analysis of RXR alpha developmental function: convergence of RXR and RAR signaling pathways in heart and eye morphogenesis.

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12 December 2020

Molecular determinants of neural crest migration

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12 December 2020

Transcriptional regulation by transforming growth factor beta of the expression of retinoic acid and retinoid X receptor genes in osteoblastic cells is mediated through AP-1.

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12 December 2020

Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain

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12 December 2020

Retinoic acid inhibits cardiac neural crest migration by blocking c-Jun N-terminal kinase activation

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12 December 2020

Endocrine regulation of HOX genes

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12 December 2020

Beta-catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis

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12 December 2020

Developmental abnormalities in cultured mouse embryos deprived of retinoic by inhibition of yolk-sac retinol binding protein synthesis

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12 December 2020

Function of the retinoic acid receptors (RARs) during development: (II) Multiple abnormalities at various stages of organogenesis in RAR double mutants

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12 December 2020

Elevated transforming growth factor beta2 enhances apoptosis and contributes to abnormal outflow tract and aortic sac development in retinoic X receptor alpha knockout embryos

1 reference

12 December 2020

Anti-retinoic acid monoclonal antibody localizes all-trans-retinoic acid in target cells and blocks normal development in early quail embryo.

1 reference

12 December 2020

Acidic fibroblast growth factor and heart development. Role in myocyte proliferation and capillary angiogenesis.

1 reference

12 December 2020

Characterization of a new member of the fatty acid-binding protein family that binds all-trans-retinol

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12 December 2020

The evolutionary origin of cardiac chambers.

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12 December 2020

Isotretinoin: new therapy for severe acne

1 reference

12 December 2020

Retinoic acid induces transforming growth factor-beta 2 in cultured keratinocytes and mouse epidermis

1 reference

12 December 2020

Identifiers

DOI

10.1100/TSW.2008.39

1 reference

18 April 2018

PMC publication ID

2559957

1 reference

18 April 2018

PubMed publication ID

18661045

1 reference

18 April 2018