(Q51961245)

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The spatio-temporal and subcellular expression of the candidate Down syndrome gene Mnb/Dyrk1A in the developing mouse brain suggests distinct sequential roles in neuronal development.

scientific article published in March 2008

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

19 April 2018

http://europepmc.org/abstract/MED/18364031

The spatio-temporal and subcellular expression of the candidate Down syndrome gene Mnb/Dyrk1A in the developing mouse brain suggests distinct sequential roles in neuronal development. (English)

1 reference

Europe PubMed Central

PubMed publication ID

19 April 2018

http://europepmc.org/abstract/MED/18364031

1 reference

based on heuristic

inferred from title

Francisco J. Tejedor

3

1 reference

Europe PubMed Central

PubMed publication ID

19 April 2018

http://europepmc.org/abstract/MED/18364031

author name string

Barbara Hämmerle

1

1 reference

Europe PubMed Central

PubMed publication ID

19 April 2018

http://europepmc.org/abstract/MED/18364031

Carina Elizalde

2

1 reference

Europe PubMed Central

PubMed publication ID

19 April 2018

http://europepmc.org/abstract/MED/18364031

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publication date

1 March 2008

1 reference

Europe PubMed Central

PubMed publication ID

19 April 2018

http://europepmc.org/abstract/MED/18364031

European Journal of Neuroscience

1 reference

Europe PubMed Central

PubMed publication ID

19 April 2018

http://europepmc.org/abstract/MED/18364031

27

1 reference

Europe PubMed Central

PubMed publication ID

19 April 2018

http://europepmc.org/abstract/MED/18364031

5

1 reference

Europe PubMed Central

PubMed publication ID

19 April 2018

http://europepmc.org/abstract/MED/18364031

1061-1074

1 reference

Europe PubMed Central

PubMed publication ID

19 April 2018

http://europepmc.org/abstract/MED/18364031

MNB/DYRK1A phosphorylation regulates the interactions of synaptojanin 1 with endocytic accessory proteins

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

DYRK1A BAC transgenic mice show altered synaptic plasticity with learning and memory defects

1 reference

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21 January 2018

Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

DYRK1A accumulates in splicing speckles through a novel targeting signal and induces speckle disassembly

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Chromosome 21 and down syndrome: from genomics to pathophysiology

1 reference

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21 January 2018

NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21.

1 reference

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21 January 2018

Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

On dendrites in Down syndrome and DS murine models: a spiny way to learn.

1 reference

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21 January 2018

Alterations in the phenotype of neocortical pyramidal cells in the Dyrk1A+/- mouse

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Transgenic mouse in vivo library of human Down syndrome critical region 1: association between DYRK1A overexpression, brain development abnormalities, and cell cycle protein alteration

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Cell output, cell cycle duration and neuronal specification: a model of integrated mechanisms of the neocortical proliferative process

1 reference

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21 January 2018

Concurrent generation of subplate and cortical plate neurons in developing trisomy 16 mouse cortex

1 reference

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21 January 2018

Dynamin is a minibrain kinase/dual specificity Yak1-related kinase 1A substrate

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Dendritic arbor development and synaptogenesis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

The neurobiologic consequences of Down syndrome

1 reference

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21 January 2018

Alterations of neocortical pyramidal cell phenotype in the Ts65Dn mouse model of Down syndrome: effects of environmental enrichment

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Trisomy-driven overexpression of DYRK1A kinase in the brain of subjects with Down syndrome

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Constitutive Dyrk1A is abnormally expressed in Alzheimer disease, Down syndrome, Pick disease, and related transgenic models

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Dyrk1A haploinsufficiency affects viability and causes developmental delay and abnormal brain morphology in mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

The MNB/DYRK1A protein kinase: genetic and biochemical properties

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Mouse models of Down syndrome: how useful can they be? Comparison of the gene content of human chromosome 21 with orthologous mouse genomic regions

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: phosphorylation by DYRK1A and colocalization with splicing factors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

The protein kinase DYRK1A phosphorylates the splicing factor SF3b1/SAP155 at Thr434, a novel in vivo phosphorylation site

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

A human homologue of Drosophila minibrain (MNB) is expressed in the neuronal regions affected in Down syndrome and maps to the critical region

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Human minibrain homologue (MNBH/DYRK1): characterization, alternative splicing, differential tissue expression, and overexpression in Down syndrome

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Translocation of cyclin B1 to the nucleus at prophase requires a phosphorylation-dependent nuclear import signal

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Mnb/Dyrk1A is transiently expressed and asymmetrically segregated in neural progenitor cells at the transition to neurogenic divisions.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

The MNB/DYRK1A protein kinase: neurobiological functions and Down syndrome implications

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Expression patterns and subcellular localization of the Down syndrome candidate protein MNB/DYRK1A suggest a role in late neuronal differentiation.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Expression of the antiproliferative gene TIS21 at the onset of neurogenesis identifies single neuroepithelial cells that switch from proliferative to neuron-generating division

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Dendritic anomalies in disorders associated with mental retardation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Dyrk, a dual specificity protein kinase with unique structural features whose activity is dependent on tyrosine residues between subdomains VII and VIII

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Down syndrome phenotypes: the consequences of chromosomal imbalance

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Patterns of neuronal migration in the embryonic cortex

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

CNS stem cells express a new class of intermediate filament protein

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Dyrk1A expression pattern supports specific roles of this kinase in the adult central nervous system

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Motor phenotypic alterations in TgDyrk1a transgenic mice implicate DYRK1A in Down syndrome motor dysfunction

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Phosphorylation of amphiphysin I by minibrain kinase/dual-specificity tyrosine phosphorylation-regulated kinase, a kinase implicated in Down syndrome

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

p27kip1 independently promotes neuronal differentiation and migration in the cerebral cortex

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

High-level expression of the Mnb/Dyrk1A gene in brain and heart during rat early development.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Expression patterns of homeobox and other putative regulatory genes in the embryonic mouse forebrain suggest a neuromeric organization

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Forebrain gene expression domains and the evolving prosomeric model.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Critical role of the D21S55 region on chromosome 21 in the pathogenesis of Down syndrome

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Expression of the mnb (dyrk) protein in adult and embryonic mouse tissues

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Understanding the basis for Down syndrome phenotypes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

The murine Dyrk protein maps to chromosome 16, localizes to the nucleus, and can form multimers

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Cellular and genetic regulation of the development of the cerebellar system

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

minibrain: a new protein kinase family involved in postembryonic neurogenesis in Drosophila

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Cell type- and brain structure-specific patterns of distribution of minibrain kinase in human brain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Protein kinase Dyrk1 activates cAMP response element-binding protein during neuronal differentiation in hippocampal progenitor cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06092.X

21 January 2018

Identifiers

10.1111/J.1460-9568.2008.06092.X

1 reference

Europe PubMed Central

PubMed publication ID

19 April 2018

http://europepmc.org/abstract/MED/18364031

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 April 2018

http://europepmc.org/abstract/MED/18364031

ResearchGate publication ID

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