(Q52015994)

English

Using meta-analysis to explain the diversity of results in genetic studies of late-onset Alzheimer's disease and to identify high-risk subgroups.

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Europe PubMed Central

19 April 2018

http://europepmc.org/abstract/MED/11738493

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Using meta-analysis to explain the diversity of results in genetic studies of late-onset Alzheimer's disease and to identify high-risk subgroups. (English)

1 reference

Europe PubMed Central

19 April 2018

http://europepmc.org/abstract/MED/11738493

0 references

Alzheimer's disease

1 reference

based on heuristic

inferred from title

author name string

Lehmann DJ

1

1 reference

Europe PubMed Central

19 April 2018

http://europepmc.org/abstract/MED/11738493

Williams J

2

1 reference

Europe PubMed Central

19 April 2018

http://europepmc.org/abstract/MED/11738493

McBroom J

3

1 reference

Europe PubMed Central

19 April 2018

http://europepmc.org/abstract/MED/11738493

Smith AD

4

1 reference

Europe PubMed Central

19 April 2018

http://europepmc.org/abstract/MED/11738493

language of work or name

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publication date

1 January 2001

1 reference

Europe PubMed Central

19 April 2018

http://europepmc.org/abstract/MED/11738493

1 reference

Europe PubMed Central

19 April 2018

http://europepmc.org/abstract/MED/11738493

108

1 reference

Europe PubMed Central

19 April 2018

http://europepmc.org/abstract/MED/11738493

541-554

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Europe PubMed Central

19 April 2018

http://europepmc.org/abstract/MED/11738493

4

1 reference

Europe PubMed Central

19 April 2018

http://europepmc.org/abstract/MED/11738493

Genetic Polymorphisms and Disease

1 reference

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7 January 2021

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The butyrylcholinesterase K variant is a protective factor for sporadic Alzheimer's disease in women.

1 reference

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7 January 2021

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The role of heredity in late-onset Alzheimer disease and vascular dementia. A twin study

1 reference

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7 January 2021

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Candidate genes showing no evidence for association or linkage with Alzheimer's disease using family-based methodologies.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

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Apo E allele frequencies in Alzheimer's disease, Lewy body dementia, Alzheimer's disease with cerebrovascular disease and vascular dementia

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

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Analysis of the butyrylcholinesterase gene and nearby chromosome 3 markers in Alzheimer disease

1 reference

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7 January 2021

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A pharmacogenomic approach to Alzheimer's disease.

1 reference

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7 January 2021

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Apolipoprotein E, epsilon 4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: analysis of the 19q13.2 chromosomal region.

1 reference

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7 January 2021

based on heuristic

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Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

1 reference

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7 January 2021

based on heuristic

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The butyrylcholinesterase gene is neither independently nor synergistically associated with late-onset AD in clinic- and community-based populations.

1 reference

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7 January 2021

based on heuristic

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The number of trait loci in late-onset Alzheimer disease

1 reference

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7 January 2021

based on heuristic

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Bias in meta-analysis detected by a simple, graphical test

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

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SNP association studies in Alzheimer's disease highlight problems for complex disease analysis.

1 reference

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7 January 2021

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Impact of genomics on drug discovery and clinical medicine.

1 reference

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7 January 2021

based on heuristic

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Heritability for Alzheimer's disease: the study of dementia in Swedish twins

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Clinical and pathological correlates of apolipoprotein E ?4 in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

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Genetics of rheumatoid arthritis: confronting complexity

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of association between Alzheimer disease and the K variant of butyrylcholinesterase (BCHE-K)

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic analysis for common complex disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Butyrylcholinesterase K variant and apolipoprotein E4 genes do not act in synergy in Finnish late-onset Alzheimer's disease patients.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

The family based association test method: strategies for studying general genotype--phenotype associations.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic risk factors of sporadic Alzheimer's disease among Chinese in Taiwan

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Strategies in complex disease mapping

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

APOE*4-associated Alzheimer's disease risk is modified by alpha 1-antichymotrypsin polymorphism.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic association studies in complex diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

The butyrylcholinesterase K variant and susceptibility to Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Diagnosis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

No association between the genes for butyrylcholinesterase K variant and apolipoprotein E4 in late-onset Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

The alpha2-macroglobulin gene in AD: a population-based study and meta-analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E in Alzheimer's disease risk and case detection: a case-control study

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Family-based tests of association in the presence of linkage

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic dissection of complex traits

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Lack of association between apolipoprotein E allele epsilon 4 and sporadic Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

No association between butyrylcholinesterase K-variant and Alzheimer disease in Chinese

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Synergy between the genes for butyrylcholinesterase K variant and apolipoprotein E4 in late-onset confirmed Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Association of butyrylcholinesterase K variant with cholinesterase-positive neuritic plaques in the temporal cortex in late-onset Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E (apoE) polymorphism and its influence on ApoE concentrations in the cerebrospinal fluid in Finnish patients with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E polymorphism and Alzheimer's disease in eastern Finland.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Confirmation of association between the e4 allele of apolipoprotein E and Alzheimer's disease

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Pharmacogenomics of neurodegenerative diseases

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E genotype and Alzheimer's disease in Hong Kong elderly Chinese.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Dipeptidyl carboxypeptidase 1 (DCP1) and butyrylcholinesterase (BCHE) gene interactions with the apolipoprotein E epsilon4 allele as risk factors in Alzheimer's disease and in Parkinson's disease with coexisting Alzheimer pathology

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Butyrylcholinesterase K variant is genetically associated with late onset Alzheimer's disease in Northern Ireland

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Tests and estimates of allelic association in complex inheritance

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Accuracy of clinical operational diagnostic criteria for Alzheimer's disease in relation to different pathological diagnostic protocols.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Epidemiology of dementia in Nigeria: results from the Indianapolis-Ibadan study.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Psychiatric genetics: progress, problems, and potential

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Butyrycholinesterase K variant and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

ApoE epsilon 4 allelic association with Alzheimer's disease: independent confirmation using denaturing gradient gel electrophoresis.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Investigation of association of 13 polymorphisms in eight genes in southeastern African American Alzheimer disease patients as compared to age-matched controls

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Association of apolipoprotein E but not B with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E: a pharmacogenetic target for the treatment of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E polymorphism and Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Lack of replication of association findings in complex disease: an analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Alzheimer's disease in Finnish twins.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Linkage disequilibrium in the human genome

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

The future of genetic studies of complex human diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases I. DNA pooling

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

A model for susceptibility polymorphisms for complex diseases: apolipoprotein E and Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

K variant of butyrycholinesterase and late-onset Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

No association between the K variant of the butyrylcholinesterase gene and pathologically confirmed Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Protective effect of apoE epsilon 2 in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

ApoE allele frequencies in Italian sporadic and familial Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

A sibship test for linkage in the presence of association: the sib transmission/disequilibrium test

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Protection against Alzheimer's disease with apoE epsilon 2.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

The genetics of Alzheimer disease: current status and future prospects

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

The NINCDS-ADRDA Work Group criteria for the clinical diagnosis of probable Alzheimer's disease: a clinicopathologic study of 57 cases

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Evaluation of polymorphisms in the presenilin-1 gene and the butyrylcholinesterase gene as risk factors in sporadic Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Interpretation of results from genetic studies of multifactorial diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

A high frequency of apolipoprotein E4 isoprotein in Japanese patients with late-onset nonfamilial Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E4 allele in a population–based study of early–onset Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Ventricular enlargement in schizophrenia. A meta-analysis of studies of the ventricle:brain ratio (VBR)

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Linkage disequilibrium in isolated populations: Finland and a young sub-population of Kuusamo.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Polygenic disease: methods for mapping complex disease traits

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Further evidence for a synergistic association between APOE epsilon4 and BCHE-K in confirmed Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Butyrylcholinesterase K variant and cerebral amyloid angiopathy.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Failure to confirm a synergistic effect between the K-variant of the butyrylcholinesterase gene and the epsilon4 allele of the apolipoprotein gene in Japanese patients with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Association of the apolipoprotein E epsilon 4 allele with clinical subtypes of autopsy-confirmed Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900464-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0306-4522(01)00464-X

1 reference

Europe PubMed Central

19 April 2018

http://europepmc.org/abstract/MED/11738493

1 reference

Europe PubMed Central

19 April 2018

http://europepmc.org/abstract/MED/11738493

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