(Q52018166)

19 April 2018

title

Controlled local delivery of interleukin-2 by biodegradable polymers protects animals from experimental brain tumors and liver tumors. (English)

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19 April 2018

0 references

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6

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19 April 2018

Kam W. Leong

9

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19 April 2018

author name string

J Hanes

1

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19 April 2018

A Sills

2

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Z Zhao

3

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K W Suh

4

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B Tyler

5

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D J Brat

7

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M A Choti

8

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D M Pardoll

10

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H Brem

11

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19 April 2018

publication date

1 July 2001

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19 April 2018

published in

Pharmaceutical Research

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19 April 2018

volume

18

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19 April 2018

issue

7

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19 April 2018

page(s)

899-906

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19 April 2018

Preliminary clinical trial of immunotherapy for malignant glioma

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Paracrine immunotherapy with interleukin-2 and local chemotherapy is synergistic in the treatment of experimental brain tumors.

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Systemic and local paracrine cytokine therapies using transduced tumor cells are synergistic in treating intracranial tumors.

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The role of IL-2 secreted from genetically modified tumor cells in the establishment of antitumor immunity

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Prolonged survival of mice with glioma injected intracerebrally with double cytokine-secreting cells

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Drug delivery and targeting

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12 December 2020

Regression of bladder tumors in mice treated with interleukin 2 gene-modified tumor cells

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12 December 2020

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12 December 2020

Systemic T cell adoptive immunotherapy of malignant gliomas.

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12 December 2020

Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity

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12 December 2020

Cytokine immunotherapy of cancer with controlled release biodegradable microspheres in a human tumor xenograft/SCID mouse model

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12 December 2020

Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response

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12 December 2020

Biodegradable microspheres in drug delivery

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12 December 2020

Controlled release of interleukin-2 from biodegradable microspheres

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12 December 2020

Interleukin 2 gene transfer into tumor cells abrogates tumorigenicity and induces protective immunity

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12 December 2020

Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas. The Polymer-brain Tumor Treatment Group

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Identifiers

DOI

10.1023/A:1010963307097

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19 April 2018

PubMed ID

11496947

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19 April 2018