(Q52037916)

20 April 2018

review article

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title

DNA damage and mutation: contributors to the age-related alterations in T cell-mediated immune responses? (English)

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20 April 2018

author name string

Y A Barnett

series ordinal

1

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20 April 2018

C R Barnett

series ordinal

2

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20 April 2018

publication date

1 May 1998

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20 April 2018

Mechanisms of Ageing and Development

published in

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20 April 2018

volume

102

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20 April 2018

issue

2-3

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20 April 2018

page(s)

165-175

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20 April 2018

Telomere length predicts replicative capacity of human fibroblasts

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Dysregulation between TH1 and TH2 T cell subpopulations in the elderly

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7 January 2021

A further assessment of factors influencing measurements of thioguanine-resistant mutant frequency in circulating T-lymphocytes.

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Detection of the carrier state for an X-linked disorder, the Lesch-Nyhan syndrome, by the use of lymphocyte cloning.

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Decline in CD28+ T cells in centenarians and in long-term T cell cultures: a possible cause for both in vivo and in vitro immunosenescence

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Insights on immunological aging derived from the T lymphocyte cellular senescence model

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The effect of donor age on spontaneous and induced micronuclei

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Genomic instability and aging. Studies in centenarians (successful aging) and in patients with Down's syndrome (accelerated aging).

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The immunology of exceptional individuals: the lesson of centenarians.

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Interleukin-2 mRNA expression, lymphokine production and DNA synthesis in glutathione-depleted T cells

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Developmental and maturational changes in human blood lymphocyte subpopulations

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7 January 2021

Telomeres shorten during ageing of human fibroblasts

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Cell cycle control and cancer

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The serial cultivation of human diploid cell strains

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7 January 2021

Overexpression of mitochondrial manganese superoxide dismutase promotes the survival of tumor cells exposed to interleukin-1, tumor necrosis factor, selected anticancer drugs, and ionizing radiation.

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7 January 2021

Frequency of 6-thioguanine-resistant T cells is inversely related to the declining T-cell activities in aging mice

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An investigation of mutation as a function of age in humans.

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In vivo antioxidant status, DNA damage, mutation and DNA repair capacity in cultured lymphocytes from healthy 75- to 80-year-old humans

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Instability and decay of the primary structure of DNA

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Immunosuppression by D-penicillamine in vitro. Inhibition of human T lymphocyte proliferation by copper- or ceruloplasmin-dependent generation of hydrogen peroxide and protection by monocytes

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7 January 2021

In vivo estimates of division and death rates of human T lymphocytes

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7 January 2021

Lifespan of human lymphocyte subsets defined by CD45 isoforms

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7 January 2021

Human lymphocytes resistant to 6-thioguanine increase with age.

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7 January 2021

Age-dependent accumulation of alkali-labile sites in DNA of post-mitotic but not in that of mitotic rat liver cells

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7 January 2021

Protein, lipid and DNA repair systems in oxidative stress: the free-radical theory of aging revisited

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7 January 2021

The T cell in the ageing individual

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Reduced proliferation rate of hypoxanthine-phosphoribosyl transferase mutant human T-lymphocytes in vitro.

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Basal DNA damage in individual human lymphocytes with age.

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7 January 2021

DNA adducts and chronic degenerative disease. Pathogenetic relevance and implications in preventive medicine.

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Successful use of short-term tests for academic purposes: Their use in identification of new environmental carcinogens with possible risk for humans

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7 January 2021

Use of the clonal assay for the measurement of frequencies of HPRT mutants in T-lymphocytes from five control populations

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7 January 2021

Mutation frequency in human lymphocytes increases with age

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7 January 2021

Measurement of spontaneous and X-irradiation-induced 6-thioguanine-resistant human blood lymphocytes using a T-cell cloning technique.

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7 January 2021

The multistep nature of cancer

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7 January 2021

Induction of manganous superoxide dismutase by tumor necrosis factor: possible protective mechanism

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7 January 2021

DNA damage and cell cycle checkpoints

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7 January 2021

10.1016/S0047-6374(98)00018-9

Identifiers

DOI

1 reference

20 April 2018

1 reference

20 April 2018