(Q52043660)

20 April 2018

title

Diminished activation of the MAP kinase pathway in CD3-stimulated T lymphocytes from old mice. (English)

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20 April 2018

author name string

Gorgas G

1

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20 April 2018

Butch ER

2

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20 April 2018

Guan KL

3

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20 April 2018

Miller RA

4

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20 April 2018

publication date

1 March 1997

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20 April 2018

Mechanisms of Ageing and Development

published in

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20 April 2018

volume

94

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20 April 2018

issue

1-3

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20 April 2018

page(s)

71-83

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20 April 2018

Diminished calcium influx in lectin-stimulated T cells from old mice

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Activation of murine T-cells via phospholipase-C gamma 1-associated protein tyrosine phosphorylation is reduced with aging

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Tyrosine-specific protein phosphorylation in response to anti-CD3 antibody is diminished in old mice

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Rapid tyrosine phosphorylation of Grb2 and Shc in T cells exposed to anti-CD3, anti-CD4, and anti-CD45 stimuli: differential effects of aging

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Age-associated changes in mitogen-induced protein phosphorylation in murine T lymphocytes.

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Decline, in aging mice, of the anti-2,4,6-trinitrophenyl (TNP) cytotoxic T cell response attributable to loss of Lyt-2-, interleukin 2-producing helper cell function

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Decline, with age, in the proportion of mouse T cells that express IL-2 receptors after mitogen stimulation

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T lymphocyte heterogeneity in old and young mice: functional defects in T cells selected for poor calcium signal generation

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Pgp-1hi T lymphocytes accumulate with age in mice and respond poorly to concanavalin A.

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Signal transduction by lymphocyte antigen receptors

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The T cell antigen receptor: insights into organelle biology

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Extracellular signal-regulated kinases: ERKs in progress

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Rapid stimulation by insulin of a serine/threonine kinase in 3T3-L1 adipocytes that phosphorylates microtubule-associated protein 2 in vitro

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A conserved kinase cascade for MAP kinase activation in yeast.

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Phosphorylation of transcription factor p62TCF by MAP kinase stimulates ternary complex formation at c-fos promoter

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Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins

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The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

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Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases

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The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product

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Mitogen-activated Swiss mouse 3T3 RSK kinases I and II are related to pp44mpk from sea star oocytes and participate in the regulation of pp90rsk activity

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Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II.

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Cellular distribution of protein kinase C isozymes in CD3-mediated stimulation of human T lymphocytes with aging

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7 January 2021

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7 January 2021

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

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7 January 2021

Enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56 lck

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7 January 2021

Tyrosine kinase-stimulated guanine nucleotide exchange activity of Vav in T cell activation

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7 January 2021

Accumulation of hyporesponsive, calcium extruding memory T cells as a key feature of age-dependent immune dysfunction

1 reference

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7 January 2021

10.1016/S0047-6374(96)01857-X

Identifiers

DOI

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20 April 2018

PubMed ID

9147361

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20 April 2018