(Q52044089)

20 April 2018

title

A novel prolyl endopeptidase inhibitor, JTP-4819, with potential for treating Alzheimer's disease. (English)

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20 April 2018

author name string

K Toide

1

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20 April 2018

M Shinoda

2

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20 April 2018

Y Iwamoto

3

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20 April 2018

T Fujiwara

4

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20 April 2018

K Okamiya

5

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20 April 2018

A Uemura

6

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20 April 2018

language of work or name

English

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publication date

1 February 1997

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20 April 2018

Behavioural Brain Research

published in

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20 April 2018

volume

83

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20 April 2018

issue

1-2

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20 April 2018

page(s)

147-151

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20 April 2018

Deficiency of kallikrein-like enzyme activities in cerebral tissue of patients with Alzheimer's disease.

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Substance P-like immunoreactivity is reduced in Alzheimer's disease cerebral cortex

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Alzheimer's Disease: A Disorder of Cortical Cholinergic Innervation

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Cortical substance P-like immunoreactivity in cases of Alzheimer's disease and senile dementia of the Alzheimer type

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Central target for the behavioural effects of vasopressin neuropeptides

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Subcellular distribution of prolyl endopeptidase and cation-sensitive neutral endopeptidase in rabbit brain.

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Neuropeptides in Alzheimer type dementia

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Reduction of arginine-vasopressin in the cerebral cortex in Alzheimer type senile dementia

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Neuropeptide substance P improves water maze performance in aged rats

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Neuropeptides and Alzheimer's disease

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Influence of region-specific alterations of neuropeptidase content on the catabolic fates of neuropeptides in Alzheimer's disease.

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Vasopressin in Alzheimer's disease: a study of postmortem brain concentrations.

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Spatial localization does not require the presence of local cues

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Effect of a novel prolyl endopeptidase inhibitor, JTP-4819, on thyrotropin-releasing hormone-like immunoreactivity in the cerebral cortex and hippocampus of aged rats

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CSF and plasma vasopressin concentrations in dementia

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Focal Cerebral Ischaemia in the Rat: 1. Description of Technique and Early Neuropathological Consequences following Middle Cerebral Artery Occlusion

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7 January 2021

Catabolism of neuropeptides by a brain proline endopeptidase

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7 January 2021

Effect of a novel prolyl endopeptidase inhibitor, JTP-4819, on neuropeptide metabolism in the rat brain.

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7 January 2021

Effect of a novel prolyl endopeptidase inhibitor, JTP-4819, on prolyl endopeptidase activity and substance P- and arginine-vasopressin-like immunoreactivity in the brains of aged rats.

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7 January 2021

Effects of a novel thyrotropin-releasing hormone analogue, JTP-2942, on extracellular acetylcholine and choline levels in the rat frontal cortex and hippocampus.

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7 January 2021

Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain

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7 January 2021

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7 January 2021

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

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7 January 2021

Post-Proline Cleaving Enzyme (Prolyl Endoeptidase) from Bovine Brain1

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7 January 2021

Post-proline cleaving enzyme. Synthesis of a new fluorogenic substrate and distribution of the endopeptidase in rat tissues and body fluids of man

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7 January 2021

10.1016/S0166-4328(97)86059-7

Identifiers

DOI

1 reference

20 April 2018

PubMed ID

9062674

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20 April 2018