(Q52128471)

English

Transforming growth factor beta (TGFbeta) mediates Schwann cell death in vitro and in vivo: examination of c-Jun activation, interactions with survival signals, and the relationship of TGFbeta-mediated death to Schwann cell differentiation.

scientific article published in November 2001

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Europe PubMed Central

PubMed publication ID

22 April 2018

http://europepmc.org/abstract/MED/11606645

Transforming growth factor beta (TGFbeta) mediates Schwann cell death in vitro and in vivo: examination of c-Jun activation, interactions with survival signals, and the relationship of TGFbeta-mediated death to Schwann cell differentiation (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762809&resulttype=core&format=json

12 May 2020

0 references

cell differentiation

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762809&resulttype=core&format=json

12 May 2020

author name string

D B Parkinson

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762809&resulttype=core&format=json

12 May 2020

Z Dong

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762809&resulttype=core&format=json

12 May 2020

H Bunting

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762809&resulttype=core&format=json

12 May 2020

J Whitfield

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762809&resulttype=core&format=json

12 May 2020

C Meier

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762809&resulttype=core&format=json

12 May 2020

R Mirsky

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762809&resulttype=core&format=json

12 May 2020

K R Jessen

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762809&resulttype=core&format=json

12 May 2020

language of work or name

0 references

publication date

1 November 2001

1 reference

Europe PubMed Central

PubMed publication ID

22 April 2018

http://europepmc.org/abstract/MED/11606645

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762809&resulttype=core&format=json

12 May 2020

21

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762809&resulttype=core&format=json

12 May 2020

21

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762809&resulttype=core&format=json

12 May 2020

8572-8585

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762809&resulttype=core&format=json

12 May 2020

The Schwann cell precursor and its fate: a study of cell death and differentiation during gliogenesis in rat embryonic nerves.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor-beta blocks myelination but not ensheathment of axons by Schwann cells in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TAK1 participates in c-Jun N-terminal kinase signaling during Drosophila development

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of endogenous transforming growth factors beta prevents ontogenetic neuron death

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcription factor ATF2 cooperates with v-Jun to promote growth factor-independent proliferation in vitro and tumor formation in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical analysis of transcriptional activation by Jun: differential activity of c- and v-Jun

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TGF‐βs and cAMP Regulate GAP‐43 Expression in Schwann Cells and Reveal the Association of this Protein with the Trans‐Golgi Network

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspases: killer proteases

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schwann cells and their precursors emerge as major regulators of nerve development

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How cells read TGF-beta signals

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TNF-alpha and TGF-beta act synergistically to kill Schwann cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of apoptosis by the transcription factor c-Jun

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schwann cell development, differentiation and myelination

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neu differentiation factor is a neuron-glia signal and regulates survival, proliferation, and maturation of rat Schwann cell precursors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Bcl-2 family and cell death regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor-beta1 and glial growth factor 2 reduce neurotrophin-3 mRNA expression in cultured Schwann cells via a cAMP-dependent pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presence and regulation of transforming growth factor beta mRNA and protein in the normal and lesioned rat sciatic nerve

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic evidence for cell death mediated by nerve growth factor and the neurotrophin receptor p75 in the developing mouse retina and spinal cord.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schwann cells: early lineage, regulation of proliferation and control of myelin formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The differential control of c-jun expression in regenerating sensory neurons and their associated glial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant transforming growth factor type beta 3: biological activities and receptor-binding properties in isolated bone cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Response of Schwann cells to mitogens in vitro is determined by pre-exposure to serum, time in vitro, and developmental age

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional control by the TGF-beta/Smad signaling system

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential and antagonistic effects of v-Jun and c-Jun

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leukemia Inhibitory Factor Is an Autocrine Survival Factor for Schwann Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of caspases and possible involvement of retinoblastoma protein during TGFbeta-mediated apoptosis of human B lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schwann cell apoptosis at developing neuromuscular junctions is regulated by glial growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fibroblast growth factors and insulin growth factors combine to promote survival of rat Schwann cell precursors without induction of DNA synthesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid and preferential activation of the c-jun gene during the mammalian UV response

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of c‐Jun, Jun B, Jun D and cAMP Response Element Binding Protein by Schwann Cells and their Precursors In Vivo and In Vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor-beta 1 regulates axon/Schwann cell interactions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Axons modulate the expression of transforming growth factor-betas in Schwann cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schwann cell development in embryonic mouse nerves.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Active killing of neurons during development and following stress: a role for p75(NTR) and Fas?

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the hematopoietic progenitor kinase-1 (HPK1)-dependent, stress-activated c-Jun N-terminal kinase (JNK) pathway by transforming growth factor beta (TGF-beta)-activated kinase (TAK1), a kinase mediator of TGF beta signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell death in the Schwann cell lineage and its regulation by neuregulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ultraviolet-radiation induced c-jun gene transcription: two AP-1 like binding sites mediate the response

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conditional cell transformation by doxycycline-controlled expression of the ASV17 v-jun allele

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor-I and Bcl-X(L) inhibit c-jun N-terminal kinase activation and rescue Schwann cells from apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteases to die for

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of multiple proteases during Fas-mediated apoptosis in T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expressing antisense P0 RNA in Schwann cells perturbs myelination

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of schwann cell phenotype by TGF‐β1: Inhibition of P0 mRNA expression and downregulation of the low affinity NGF receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle-dependent variations in c-Jun and JunB phosphorylation: a role in the control of cyclin D1 expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The v-Jun oncoprotein replaces p39 c-Jun as the predominant AP-1 constituent in ASV17-transformed fibroblasts: implications for SAPK/JNK-mediated signal transduction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Negative regulation of the P0 gene in Schwann cells: suppression of P0 mRNA and protein induction in cultured Schwann cells by FGF2 and TGF beta 1, TGF beta 2 and TGF beta 3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional activation by the v-Jun oncoprotein is independent of positive regulatory phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The JUN oncoprotein, a vertebrate transcription factor, activates transcription in yeast.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Scale-up of the adenovirus expression system for the production of recombinant protein in human 293S cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone (Z-VAD.FMK) inhibits apoptosis by blocking the processing of CPP32.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of adenovirus vectors for the expression of heterologous genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A zinc-finger transcription factor induced by TGF-beta promotes apoptotic cell death in epithelial Mv1Lu cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and transcriptional regulation of BKJ, a novel AP-1 target gene activated during jun- or fos-induced fibroblast transformation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An ICE-like protease is a common mediator of apoptosis induced by diverse stimuli in human monocytic THP.1 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Axonal interactions regulate Schwann cell apoptosis in developing peripheral nerve: neuregulin receptors and the role of neuregulins

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cultured Schwann cells constitutively express the myelin protein P0

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of caspase-8 in transforming growth factor-beta-induced apoptosis of human hepatoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developing Schwann cells acquire the ability to survive without axons by establishing an autocrine circuit involving insulin-like growth factor, neurotrophin-3, and platelet-derived growth factor-BB.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor signaling through p75 induces apoptosis in Schwann cells via a Bcl-2-independent pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophins in cell survival/death decisions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of cell death by endogenous nerve growth factor through its p75 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of cAMP on differentiation of cultured Schwann cells: progression from an early phenotype (04+) to a myelin phenotype (P0+, GFAP-, N-CAM-, NGF-receptor-) depends on growth inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oct-6 (SCIP/Tst-1) is expressed in Schwann cell precursors, embryonic Schwann cells, and postnatal myelinating Schwann cells: comparison with Oct-1, Krox-20, and Pax-3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TGF-betas upregulate NCAM and L1 expression in cultured Schwann cells, suppress cyclic AMP-induced expression of O4 and galactocerebroside, and are widely expressed in cells of the Schwann cell lineage in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transformation by v-Jun prevents cell cycle exit and promotes apoptosis in the absence of serum growth factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11606645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.21-21-08572.2001

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762809&resulttype=core&format=json

12 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762809&resulttype=core&format=json

12 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762809&resulttype=core&format=json

12 May 2020

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