(Q52130337)

22 April 2018

title

Somatic activation of beta-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development. (English)

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22 April 2018

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Gounari F

1

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22 April 2018

Aifantis I

2

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22 April 2018

Khazaie K

3

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22 April 2018

Hoeflinger S

4

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22 April 2018

Harada N

5

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22 April 2018

Taketo MM

6

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22 April 2018

von Boehmer H

7

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22 April 2018

language of work or name

English

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publication date

1 September 2001

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22 April 2018

published in

Nature Immunology

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22 April 2018

volume

2

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22 April 2018

issue

9

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22 April 2018

page(s)

863-869

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22 April 2018

Early T lymphocyte progenitors

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A novel disulfide-linked heterodimer on pre-T cells consists of the T cell receptor beta chain and a 33 kd glycoprotein

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Pleiotropic changes controlled by the pre-T-cell receptor

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RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

21 January 2018

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21 January 2018

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FADD/MORT1 regulates the pre-TCR checkpoint and can function as a tumour suppressor

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Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice

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Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages

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21 January 2018

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21 January 2018

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7 January 2021

NF-kappa B activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development

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Pre-TCR signaling and inactivation of p53 induces crucial cell survival pathways in pre-T cells

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Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points

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7 January 2021

Identifiers

DOI

10.1038/NI0901-863

1 reference

22 April 2018

1 reference

22 April 2018