(Q52241373)

27 April 2018

title

A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting (English)

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27 April 2018

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DeChiara TM

1

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27 April 2018

Efstratiadis A

series ordinal

2

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27 April 2018

Robertson EJ

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3

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27 April 2018

publication date

1 May 1990

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27 April 2018

language of work or name

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volume

345

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issue

6270

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page(s)

78-80

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27 April 2018

Fetal growth control: the role of insulin and related peptides

cites work

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7 January 2021

Growth factors in early embryogenesis

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7 January 2021

Insulin-like growth factors/somatomedins: structure, secretion, biological actions and physiological role

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7 January 2021

Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations

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7 January 2021

Rat insulin-like growth factor II gene. A single gene with two promoters expressing a multitranscript family

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7 January 2021

The gene structure of the insulin-like growth factor family

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7 January 2021

A promoter of the rat insulin-like growth factor II gene consists of minimal control elements

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7 January 2021

A new leader exon identified in the rat insulin-like growth factor II gene

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7 January 2021

Expression of the insulin-like growth factor II gene in the choroid plexus and the leptomeninges of the adult rat central nervous system

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7 January 2021

Establishment in culture of pluripotential cells from mouse embryos

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7 January 2021

Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells

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7 January 2021

Insertion of DNA sequences into the human chromosomal beta-globin locus by homologous recombination

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7 January 2021

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

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Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

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Altering the genome by homologous recombination

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Targeted mutation of the Hprt gene in mouse embryonic stem cells

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Production of chimaeric mice containing embryonic stem (ES) cells carrying a homoeobox Hox 1.1 allele mutated by homologous recombination

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Production of a mutation in mouse En-2 gene by homologous recombination in embryonic stem cells

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Targeting of nonexpressed genes in embryonic stem cells via homologous recombination

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Inactivating the beta 2-microglobulin locus in mouse embryonic stem cells by homologous recombination

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7 January 2021

Germ-line transmission of a disrupted beta 2-microglobulin gene produced by homologous recombination in embryonic stem cells

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7 January 2021

Germ-line transmission of a c-abl mutation produced by targeted gene disruption in ES cells

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Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines

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Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector

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The pIC plasmid and phage vectors with versatile cloning sites for recombinant selection by insertional inactivation

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7 January 2021

Recombinant fragment assay for gene targetting based on the polymerase chain reaction

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7 January 2021

Identifiers

DOI

10.1038/345078A0

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27 April 2018

Dimensions Publication ID

1033319950

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27 April 2018