(Q52299587)

28 April 2018

title

Volumes of distribution and mean residence time of drugs with linear tissue distribution and binding and nonlinear protein binding. (English)

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28 April 2018

author name string

H Cheng

series ordinal

1

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28 April 2018

W R Gillespie

series ordinal

2

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28 April 2018

publication date

1 August 1996

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28 April 2018

Journal of Pharmacokinetics and Pharmacodynamics

published in

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28 April 2018

volume

24

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28 April 2018

issue

4

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28 April 2018

page(s)

389-402

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28 April 2018

Factors affecting drug metabolism

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Simple model to explain effects of plasma protein binding and tissue binding on calculated volumes of distribution, apparent elimination rate constants and clearances

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Effect of Altered Plasma Protein Binding on Apparent Volume of Distribution

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21 January 2018

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Distribution volume related to body weight and protein binding

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Volume of distribution terms for a drug (ceftriaxone) exhibiting concentration-dependent protein binding. I. Theoretical considerations.

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Theorems and implications of a model-independent elimination/distribution function decomposition of linear and some nonlinear drug dispositions. II. Clearance concepts applied to the evaluation of distribution kinetics.

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Determination of Common Parameters of Iodothyronine Metabolism and Distribution in Man by Noncompartmental Analysis

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Noncompartmental Determination of the Steady‐State Volume of Distribution

21 January 2018

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Mean residence time concepts for pharmacokinetic systems with nonlinear drug elimination described by the Michaelis-Menten equation.

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Volume of distribution terms for a drug (ceftriaxone) exhibiting concentration-dependent protein binding. II. Physiological significance.

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Regarding dose-independent pharmacokinetic parameters in nonlinear pharmacokinetics.

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Kinetics of Elimination of Drugs Possessing High Affinity for the Plasma Proteins

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Dose-Dependent Protein Binding and Disposition of Prednisolone in Rabbits

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12 December 2020

Effect of saturable binding on the pharmacokinetics of drugs: a simulation

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12 December 2020

Numerical Solution of Nonlinear Pharmacokinetic Equations: Effects of Plasma Protein Binding on Drug Distribution and Elimination

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Pharmacokinetic models regarding protein binding of drugs

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12 December 2020

The disposition of propranolol. 3. Decreased half-life and volume of distribution as a result of plasma binding in man, monkey, dog and rat

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12 December 2020

Effect of plasma protein and tissue binding on the time course of drug concentration in plasma

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12 December 2020

Comparative Pharmacokinetics of Coumarin Anticoagulants XIV: Relationship between Protein Binding, Distribution, and Elimination Kinetics of Warfarin in Rats

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Identifiers

DOI

10.1007/BF02353519

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28 April 2018

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28 April 2018