(Q52341070)

29 April 2018

title

IpdAB, a virulence factor in Mycobacterium tuberculosis, is a cholesterol ring-cleaving hydrolase. (English)

1 reference

29 April 2018

Mycobacterium tuberculosis

main subject

1 reference

Adam M Crowe

1

1 reference

29 April 2018

Sean D Workman

2

1 reference

29 April 2018

Nobuhiko Watanabe

3

1 reference

29 April 2018

Liam J Worrall

4

1 reference

29 April 2018

Natalie C J Strynadka

5

1 reference

29 April 2018

Lindsay D Eltis

6

1 reference

29 April 2018

language of work or name

English

0 references

publication date

26 March 2018

1 reference

29 April 2018

Proceedings of the National Academy of Sciences of the United States of America

published in

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29 April 2018

volume

115

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29 April 2018

issue

15

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29 April 2018

page(s)

E3378-E3387

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29 April 2018

Functional Dissection of the Bipartite Active Site of the Class I Coenzyme A (CoA)-Transferase Succinyl-CoA:Acetate CoA-Transferase

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Novel inhibitors of cholesterol degradation in Mycobacterium tuberculosis reveal how the bacterium's metabolism is constrained by the intracellular environment

25 August 2018

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FadA5 a thiolase from Mycobacterium tuberculosis: a steroid-binding pocket reveals the potential for drug development against tuberculosis

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25 August 2018

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Biotechnological opportunities with the β-ketoadipate pathway

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Activity of 3-ketosteroid 9α-hydroxylase (KshAB) indicates cholesterol side chain and ring degradation occur simultaneously in Mycobacterium tuberculosis

25 August 2018

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25 August 2018

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3-Ketosteroid 9alpha-hydroxylase is an essential factor in the pathogenesis of Mycobacterium tuberculosis

25 August 2018

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A thiolase of Mycobacterium tuberculosis is required for virulence and production of androstenedione and androstadienedione from cholesterol

25 August 2018

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Studies of a ring-cleaving dioxygenase illuminate the role of cholesterol metabolism in the pathogenesis of Mycobacterium tuberculosis

25 August 2018

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25 August 2018

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Characterization of 3-ketosteroid 9{alpha}-hydroxylase, a Rieske oxygenase in the cholesterol degradation pathway of Mycobacterium tuberculosis

25 August 2018

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25 August 2018

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Mycobacterial persistence requires the utilization of host cholesterol

25 August 2018

1 reference

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Reinvestigation of the catalytic mechanism of formyl-CoA transferase, a class III CoA-transferase

25 August 2018

1 reference

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25 August 2018

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25 August 2018

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Crystallographic trapping of the glutamyl-CoA thioester intermediate of family I CoA transferases.

25 August 2018

1 reference

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DIAL: a web-based server for the automatic identification of structural domains in proteins

25 August 2018

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Genome-wide requirements for Mycobacterium tuberculosis adaptation and survival in macrophages

25 August 2018

1 reference

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25 August 2018

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A new family of CoA-transferases

25 August 2018

1 reference

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Succinyl-CoA:(R)-benzylsuccinate CoA-transferase: an enzyme of the anaerobic toluene catabolic pathway in denitrifying bacteria

25 August 2018

1 reference

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Oxygen exchange between acetate and the catalytic glutamate residue in glutaconate CoA-transferase from Acidaminococcus fermentans. Implications for the mechanism of CoA-ester hydrolysis

25 August 2018

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Glutaconate CoA-transferase from Acidaminococcus fermentans: the crystal structure reveals homology with other CoA-transferases

25 August 2018

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Glutaconate CoA-transferase from Acidaminococcus fermentans

25 August 2018

1 reference

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The oxoacyl-coenzyme A thiolases of animal tissues

25 August 2018

1 reference

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Mechanism and specificity of succinyl-CoA:3-ketoacid coenzyme A transferase

25 August 2018

1 reference

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Characterization of the Isolated Transferase Subunit of Citrate Lyase as a CoA-Transferase. Evidence against a Covalent Enzyme-Substrate Intermediate

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5899439

The Enzyme Complex Citramalate Lyase from Clostridium tetanomorphum

25 August 2018

1 reference

12 December 2020

Isolation of an enzyme-coenzyme A intermediate from succinyl coenzyme A-acetoacetate coenzyme A transferase

1 reference

12 December 2020

6-Hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase and 6-oxocyclohex-1-ene-1-carbonyl-CoA hydrolase, enzymes of the benzoyl-CoA pathway of anaerobic aromatic metabolism in the denitrifying bacterium Thauera aromatica

1 reference

12 December 2020

Catabolism of the Last Two Steroid Rings in Mycobacterium tuberculosis and Other Bacteria

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1717015115

1 reference

29 April 2018

0 references

1 reference

29 April 2018