(Q52432446)

1 May 2018

title

The relevance of residence time theory to pharmacokinetics. (English)

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1 May 2018

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M Weiss

1

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1 May 2018

publication date

1 January 1992

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1 May 2018

European Journal of Clinical Pharmacology

published in

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1 May 2018

volume

43

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1 May 2018

issue

6

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1 May 2018

page(s)

571-579

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1 May 2018

https://scigraph.springernature.com/pub.10.1007/bf02284953

exact match

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cites work

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Comments on mean residence time determination.

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Model-independent assessment of accumulation kinetics based on moments of drug disposition curves

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Hemodynamic influences upon the variance of disposition residence time distribution of drugs.

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General treatment of mean residence time, clearance, and volume parameters in linear mammillary models with elimination from any compartment

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Sampling strategies for noncompartmental estimation of mean residence time

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Linear and nonlinear system approaches in pharmacokinetics: how much do they have to offer? I. General considerations.

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Mean time and first-pass metabolism

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The phenomenon and rationale of marked dependence of drug concentration on blood sampling site. Implications in pharmacokinetics, pharmacodynamics, toxicology and therapeutics (Part I).

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Types of mean residence times.

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Residence time and accumulation of drugs in the body

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Washout time versus mean residence time

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Pharmacokinetic evaluation of stable piecewise cubic polynomials as numerical integration functions.

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Mean residence time and the meaning of AUMC/AUC.

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Generalizations in linear pharmacokinetics using properties of certain classes of residence time distributions. I. Log-convex drug disposition curves.

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The urinary elimination "time lag": determination of the mean residence time from drug accumulation in the urine during infusion

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Estimation of mean residence time from data obtained when multiple-dosing steady state has been reached

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Model-free evaluation and mean-time concept in pharmacokinetics.

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Amiodarone disposition: polyexponential, power and gamma functions

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Nonidentity of the Steady-State Volumes of Distribution of the Eliminating and Noneliminating System

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Metabolite residence time: influence of the first-pass effect.

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The use and abuse of models

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[A simple statistical dosage metabolism law]

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Theory of the mean absorption time, an adjunct to conventional bioavailability studies

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Mean time parameters in pharmacokinetics. Definition, computation and clinical implications (Part I).

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Definition of mean residence times in pharmacokinetics

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In vitro--in vivo correlation of dissolution, a time scaling problem? Transformation of in vitro results to the in vivo situation, using theophylline as a practical example.

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A new approach to the measurement of glycerol turnover

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Pharmacokinetic stochastic model with Weibull-distributed residence times of drug molecules in the body.

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Use of gamma distributed residence times in pharmacokinetics.

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Definition of pharmacokinetic parameters: influence of the sampling site.

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Generalizations in linear pharmacokinetics using properties of certain classes of residence time distributions. II. Log-concave concentration-time curves following oral administration

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Mean residence time in the body versus mean residence time in the central compartment

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The determination of mean residence time using statistical moments: is it correct?

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Noncompartmental determination of the steady-state volume of distribution for any mode of administration.

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Intravascular mixing and drug distribution: the concurrent disposition of thiopental and indocyanine green.

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Use of metabolite AUC data in bioavailability studies to discriminate between absorption and first-pass extraction

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Curve-fitting in pharmacokinetics--a comparison between gamma- and biexponential fits

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Noncompartmental Determination of the Steady‐State Volume of Distribution

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Identifiers

DOI

10.1007/BF02284953

1 reference

1 May 2018

1 reference

1 May 2018