(Q52529169)

2 May 2018

title

Influence of the P5 residue on alpha1-proteinase inhibitor mechanism. (English)

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2 May 2018

author name string

Chaillan-Huntington CE

series ordinal

1

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2 May 2018

Patston PA

series ordinal

2

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2 May 2018

language of work or name

English

0 references

publication date

1 February 1998

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2 May 2018

Journal of Biological Chemistry

number of pages

5

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based on heuristic

inferred from page(s)

published in

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2 May 2018

volume

273

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2 May 2018

issue

8

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2 May 2018

page(s)

4569-4573

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2 May 2018

Human plasma proteinase inhibitors

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.8.4569

A 30-year perspective on alpha 1-antitrypsin deficiency

21 January 2018

1 reference

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Serpins are suicide substrates: implications for the regulation of proteolytic pathways

21 January 2018

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Inhibitory conformation of the reactive loop of alpha 1-antitrypsin

21 January 2018

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Crystal structure of an uncleaved alpha 1-antitrypsin reveals the conformation of its inhibitory reactive loop

21 January 2018

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On the size of the active site in proteases. I. Papain

21 January 2018

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Crystal structure of uncleaved ovalbumin at 1.95 A resolution

21 January 2018

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Natural protein proteinase inhibitors and their interaction with proteinases

21 January 2018

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The P6−P2 Region of Serpins Is Critical for Proteinase Inhibition and Complex Stability

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.8.4569

Major proteinase movement upon stable serpin-proteinase complex formation

21 January 2018

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Human plasma α1-proteinase inhibitor: Temporary inhibition and multiple molecular forms of the complex with porcine trypsin

21 January 2018

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Human alpha 1-proteinase inhibitor. Crystal structure analysis of two crystal modifications, molecular model and preliminary analysis of the implications for function

21 January 2018

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Significance of secondary structure predictions on the reactive center loop region of serpins: a model for the folding of serpins into a metastable state

21 January 2018

1 reference

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A fluorescent probe study of plasminogen activator inhibitor-1. Evidence for reactive center loop insertion and its role in the inhibitory mechanism

21 January 2018

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Effects of serpin binding on the target proteinase: global stabilization, localized increased structural flexibility, and conserved hydrogen bonding at the active site.

21 January 2018

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Structural change in alpha-chymotrypsin induced by complexation with alpha 1-antichymotrypsin as seen by enhanced sensitivity to proteolysis.

21 January 2018

1 reference

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Crystal structure of an uncleaved serpin reveals the conformation of an inhibitory reactive loop

21 January 2018

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Preparation and characterization of latent alpha 1-antitrypsin

21 January 2018

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Refolding of α1-antitrypsin expressed as inclusion bodies in Escherichia coli: characterization of aggregation

21 January 2018

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Kinetic and Chemical Evidence for the Inability of Oxidized α1-Proteinase Inhibitor to Protect Lung Elastin from Elastolytic Degradation

21 January 2018

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Kinetic characterization of the proteinase binding defect in a reactive site variant of the serpin, antithrombin. Role of the P1' residue in transition-state stabilization of antithrombin-proteinase complex formation

21 January 2018

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Inhibitory mechanism of serpins. Identification of steps involving the active-site serine residue of the protease

21 January 2018

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The kinetic mechanism of serpin-proteinase complex formation. An intermediate between the michaelis complex and the inhibited complex

21 January 2018

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Structural insights into serpin-protease complexes reveal the inhibitory mechanism of serpins

21 January 2018

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Distortion of the active site of chymotrypsin complexed with a serpin

21 January 2018

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Conversion of alpha 1-antichymotrypsin into a human neutrophil elastase inhibitor: demonstration of variants with different association rate constants, stoichiometries of inhibition, and complex stabilities

21 January 2018

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Heparin facilitates dissociation of complexes between thrombin and a reactive site mutant (L444R) of heparin cofactor II

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.8.4569

Heparin promotes proteolytic inactivation by thrombin of a reactive site mutant (L444R) of recombinant heparin cofactor II

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.8.4569

21 January 2018

Identifiers

DOI

10.1074/JBC.273.8.4569

1 reference

2 May 2018

1 reference

2 May 2018