(Q52531948)

2 May 2018

title

The Hsp90-specific inhibitor, geldanamycin, blocks CD28-mediated activation of human T lymphocytes. (English)

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2 May 2018

author name string

Schnaider T

1

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2 May 2018

Somogyi J

2

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2 May 2018

Csermely P

3

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2 May 2018

Szamel M

4

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2 May 2018

language of work or name

English

0 references

publication date

1 January 1998

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2 May 2018

published in

Life Sciences

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2 May 2018

volume

63

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2 May 2018

issue

11

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2 May 2018

page(s)

949-954

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2 May 2018

Molecular chaperones in cellular protein folding

cites work

1 reference

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7 January 2021

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7 January 2021

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Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent

7 January 2021

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Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone

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The hsp90-binding antibiotic geldanamycin decreases Raf levels and epidermal growth factor signaling without disrupting formation of signaling complexes or reducing the specific enzymatic activity of Raf kinase

7 January 2021

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Hsp90-mediated folding of the lymphoid cell kinase p56lck

7 January 2021

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Phenotypic change from transformed to normal induced by benzoquinonoid ansamycins accompanies inactivation of p60src in rat kidney cells infected with Rous sarcoma virus

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In vitro evidence that hsp90 contains two independent chaperone sites

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CD28/B7 system of T cell costimulation

7 January 2021

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JNK is involved in signal integration during costimulation of T lymphocytes.

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CD28-mediated activation of resting human T cells without costimulation of the CD3/TCR complex.

7 January 2021

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T cell antigen receptor dependent signalling in human lymphocytes: cholera toxin inhibits interleukin-2 receptor expression but not interleukin-2 synthesis by preventing activation of a protein kinase C isotype, PKC-alpha

7 January 2021

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Functional expression of human CD28 in murine T cell hybridomas

7 January 2021

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CD28-mediated induction of proliferation in resting T cells in vitro and in vivo without engagement of the T cell receptor: evidence for functionally distinct forms of CD28

7 January 2021

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10.1016/S0024-3205(98)00352-X

7 January 2021

Identifiers

DOI

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2 May 2018

1 reference

2 May 2018