(Q52535929)

2 May 2018

title

Design and synthesis of thrombin receptor-derived nonpeptide mimetics utilizing a piperazine scaffold. (English)

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2 May 2018

author

Thomas Mavromoustakos

6

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2 May 2018

author name string

Alexopoulos K

1

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2 May 2018

Fatseas P

2

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2 May 2018

Melissari E

3

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2 May 2018

Vlahakos D

4

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2 May 2018

Smith J

5

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2 May 2018

Saifeddine M

7

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2 May 2018

Moore G

8

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2 May 2018

Hollenberg M

9

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2 May 2018

Matsoukas J

10

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2 May 2018

language of work or name

English

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publication date

1 June 1999

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2 May 2018

Bioorganic & Medicinal Chemistry

published in

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2 May 2018

volume

7

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2 May 2018

issue

6

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2 May 2018

page(s)

1033-1041

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2 May 2018

Identification of a thrombin sequence with growth factor activity on macrophages

cites work

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Cerebral arterial contractions induced by human and bovine thrombin

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Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

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cDNA cloning and expression of a hamster alpha-thrombin receptor coupled to Ca2+ mobilization

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Domains specifying thrombin–receptor interaction

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Specificity of the thrombin receptor for agonist peptide is defined by its extracellular surface

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Essential groups in synthetic agonist peptides for activation of the platelet thrombin receptor

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Synthesis and contractile activities of cyclic thrombin receptor-derived peptide analogues with a Phe-Leu-Leu-Arg motif: importance of the Phe/Arg relative conformation and the primary amino group for activity

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7 January 2021

Conformational analysis of the thrombin receptor agonist peptides SFLLR and SFLLR-NH2 by NMR: evidence for a cyclic bioactive conformation

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2-substituted piperazines as constrained amino acids. Application to the synthesis of potent, non carboxylic acid inhibitors of farnesyltransferase

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Structure-activity relationship studies of central nervous system agents. 13. 4-[3-(Benzotriazol-1-yl)propyl]-1-(2-methoxyphenyl)piperazine, a new putative 5-HT1A receptor antagonist, and its analogs

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Synthesis and evaluation of 4-(2'-methoxyphenyl)-1-[2'-[N-(2"-pyridinyl)-p- iodobenzamido]ethyl]piperazine (p-MPPI): a new iodinated 5-HT1A ligand

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Synthesis and platelet-activating factor (PAF)-antagonistic activities of 1,4-disubstituted piperazine derivatives

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7 January 2021

Synthesis and platelet-activating factor (PAF)-antagonistic activities of trisubstituted piperazine derivatives

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7 January 2021

Inhibition of thrombin and SFLLR-peptide stimulation of platelet aggregation, phospholipase A2 and Na+/H+ exchange by a thrombin receptor antagonist

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7 January 2021

Cellular consequences of thrombin-receptor activation

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Regular physical exercise and low-fat diet. Effects on progression of coronary artery disease.

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Role of the thrombin receptor in restenosis and atherosclerosis

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Random-effects models for longitudinal data

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7 January 2021

10.1016/S0968-0896(99)00017-6

Identifiers

DOI

1 reference

2 May 2018

1 reference

2 May 2018