(Q52558839)

3 May 2018

title

Impairment of respiration and oxidative phosphorylation by redox cyclers 2-nitrosofluorene and menadione. (English)

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3 May 2018

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Klöhn PC

1

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3 May 2018

Neumann HG

series ordinal

2

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3 May 2018

publication date

1 August 1997

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3 May 2018

Chemico-biological Interactions

published in

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3 May 2018

volume

106

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3 May 2018

issue

1

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3 May 2018

page(s)

15-28

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3 May 2018

The role of nongenotoxic mechanisms in arylamine carcinogenesis

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A metabolite of carcinogenic 2-acetylaminofluorene, 2-nitrosofluorene, induces redox cycling in mitochondria.

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One-electron-transfer reactions in biochemical systems. V. Difference in the mechanism of quinone reduction by the NADH dehydrogenase and the NAD(P)H dehydrogenase (DT-diaphorase)

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Lipid peroxidation and paraquat toxicity

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Alterations in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes

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Molecular mechanisms of quinone cytotoxicity

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Menadione- (2-methyl-1,4-naphthoquinone-) dependent enzymatic redox cycling and calcium release by mitochondria

7 January 2021

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Oxidative stress in mitochondria: its relationship to cellular Ca2+ homeostasis, cell death, proliferation, and differentiation

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Alterations in energy status by menadione metabolism in hepatocytes isolated from fasted and fed rats.

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Role of thiol homeostasis and adenine nucleotide metabolism in the protective effects of fructose in quinone-induced cytotoxicity in rat hepatocytes

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Metabolic alterations in hepatocytes promoted by the herbicides paraquat, dinoseb and 2,4-D.

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Lipid peroxidation and protein thiol depletion are not involved in the cytotoxicity of N-hydroxy-2-acetylaminofluorene in isolated rat hepatocytes

7 January 2021

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Fasting increases the susceptibility of rat hepatocytes to the cytotoxic effects of N-hydroxy-acetylaminofluorene. Effects on mitochondrial respiration and membrane potential.

7 January 2021

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7 January 2021

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2-Nitrosofluorene and N-hydroxy-2-aminofluorene react with the ubiquinone-reduction center (center N) of the mitochondrial cytochrome bc1 complex

7 January 2021

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Reactions of nitrosobenzene with reduced glutathione

7 January 2021

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Reaction of arylnitroso compounds with mercaptans

7 January 2021

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Regulation of cellular energy metabolism

7 January 2021

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Mitochondrial oxidation of p-phenylenediamine derivatives in vitro: structure-activity relationships and correlation with myotoxic activity in vivo

7 January 2021

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10.1016/S0009-2797(97)00052-5

7 January 2021

Identifiers

DOI

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3 May 2018

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3 May 2018