(Q52564182)

English

Prediction of hepatic first-pass metabolism and plasma levels following intravenous and oral administration of barbiturates in the rabbit based on quantitative structure-pharmacokinetic relationships.

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/3221327

Prediction of hepatic first-pass metabolism and plasma levels following intravenous and oral administration of barbiturates in the rabbit based on quantitative structure-pharmacokinetic relationships. (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/3221327

author name string

N Watari

1

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/3221327

Y Sugiyama

2

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/3221327

N Kaneniwa

3

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/3221327

M Hiura

4

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/3221327

publication date

1 June 1988

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/3221327

Journal of Pharmacokinetics and Pharmacodynamics

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/3221327

16

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/3221327

3

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/3221327

279-301

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/3221327

https://scigraph.springernature.com/pub.10.1007/bf01062138

0 references

Quantitative structure-pharmacokinetic relationships derived on antibacterial sulfonamides in rats and its comparison to quantitative structure-activity relationships.

1 reference

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Quantitative structure pharmacokinetic activity relationships with some tetracyclines [proceedings]

1 reference

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Pharmacokinetic aspects of elimination from plasma and distribution to brain and liver of barbiturates in rat.

1 reference

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21 January 2018

Studies on Absorption of Drugs. VIII. Physicochemical Factors affecting the Absorption of Sulfonamides from the Rat Small Intestine

1 reference

https://api.crossref.org/works/10.1007%2FBF01062138

21 January 2018

Quantitative structure-pharmacokinetic relationships and drug design

1 reference

https://api.crossref.org/works/10.1007%2FBF01062138

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Drugs and Enzyme Induction

1 reference

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Effect of fasting on the elimination of barbital and phenobarbital in rabbits

1 reference

https://api.crossref.org/works/10.1007%2FBF01062138

21 January 2018

Clearance concepts in pharmacokinetics

1 reference

https://api.crossref.org/works/10.1007%2FBF01062138

21 January 2018

Commentary: a physiological approach to hepatic drug clearance

1 reference

https://api.crossref.org/works/10.1007%2FBF01062138

21 January 2018

Hepatic clearance of drugs. I. Theoretical considerations of a "well-stirred" model and a "parallel tube" model. Influence of hepatic blood flow, plasma and blood cell binding, and the hepatocellular enzymatic activity on hepatic drug clearance

1 reference

https://api.crossref.org/works/10.1007%2FBF01062138

21 January 2018

Influence of route of administration on drug availability

1 reference

https://api.crossref.org/works/10.1007%2FBF01062138

21 January 2018

Statistical moments in pharmacokinetics.

1 reference

https://api.crossref.org/works/10.1007%2FBF01062138

21 January 2018

The application of statistical moment theory to the evaluation of in vivo dissolution time and absorption time.

1 reference

https://api.crossref.org/works/10.1007%2FBF01062138

21 January 2018

A method of determining intrinsic hepatic clearance from the first-pass effect

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absorption and Excretion of Drugs. XXX. Absorption of Barbituric Acid Derivatives from Rat Stomach

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absorption of drugs from the rat colon

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of lipid solubility and dose on the elimination of barbiturates in rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exact mathematical equivalence of the venous equilibration ("well-stirred") model, the sinusoidal perfusion ("parallel-tube") model, and a specific two-compartment open model

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The behavior of intravenously injected particulate material; its rate of disappearance from the blood stream as a measure of liver blood flow

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of serum binding of penicillins with partition coefficients

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absorption and Excretion of Drugs. XXXIII. The Correlation between the Absorption of Barbituric Acid Derivatives from the Rat Small Intestine and Their Binding to the Mucosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of First-Pass Effect on Availability of Drugs on Oral Administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of radioactive microspheres to assess distribution of cardiac output in rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parabolic dependence of drug action upon lipophilic character as revealed by a study of hypnotics

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between the lipid solubility of drugs and their oxidation by liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between difference spectra and metabolism. Barbiturates, drug interaction and species difference

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biological activities of drugs. IV. Physicochemical factors affecting the excretion of sulfonamides in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabolism of barbiturates

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative structure-pharmacokinetics relationships and their importance in drug design, possibilities and limitations

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetics of pharmacologic effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mean hepatic transit time in the determination of mean absorption time

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzymatic elimination of substrates flowing through the intact liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-pharmacokinetic relationships among the barbiturates in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ABSORPTION AND EXCRETION OF DRUGS. XXI. SOME PHARMACOKINETIC ASPECTS OF ABSORPTION AND EXCRETION OF SULFONAMIDES. (3). EXCRETION FROM THE KIDNEY

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Further studies using carbamate esters as model compounds to investigate the role of lipophilicity in the gastrointestinal absorption of foreign compounds

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of the volume of distribution from in vitro data and use for estimating the absolute extent of absorption.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of nonlinear pharmacokinetic parameters estimated from the sinusoidal perfusion and venous equilibrium models.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A study of the interaction of a series of substituted barbituric acids with the hepatic microsomal monooxygenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ks values of some homologous series of barbiturates and the relationship with the lipophilicity and metabolic clearance

1 reference

https://pubmed.ncbi.nlm.nih.gov/3221327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF01062138

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/3221327

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/3221327

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