(Q52575951)

English

1-Methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (salsolinol) is toxic to dopaminergic neuroblastoma SH-SY5Y cells via impairment of cellular energy metabolism.

scientific article published in February 2000

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Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/10650131

1-Methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (salsolinol) is toxic to dopaminergic neuroblastoma SH-SY5Y cells via impairment of cellular energy metabolism. (English)

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Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/10650131

1 reference

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author name string

Storch A

1

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Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/10650131

Kaftan A

2

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/10650131

Burkhardt K

3

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/10650131

Schwarz J

4

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Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/10650131

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publication date

1 February 2000

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Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/10650131

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/10650131

855

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/10650131

1

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/10650131

67-75

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/10650131

Effects of 1-methyl-4-phenylpyridinium on isolated rat brain mitochondria: evidence for a primary involvement of energy depletion

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An endogenous dopaminergic neurotoxin, N-methyl-(R)-salsolinol, induces DNA damage in human dopaminergic neuroblastoma SH-SY5Y cells

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Inhibition of α-Ketoglutarate dehydrogenase by isoquinoline derivatives structurally related to 1 -methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

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Isoquinoline derivatives as endogenous neurotoxins in the aetiology of Parkinson's disease

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Inhibition of complex I by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)

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Effects of salsolinol on cultivated endothelial cells

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Toxicity of 1-methyl-4-phenylpyridinium for rat dopaminergic neurons in culture: selectivity and irreversibility

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An immunohistochemical study on alpha-ketoglutarate dehydrogenase complex in Parkinson's disease

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Deficiencies in complex I subunits of the respiratory chain in Parkinson's disease

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Inhibition of mitochondrial NADH-ubiquinone oxidoreductase activity by 1-methyl-4-phenylpyridinium ion

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Effect of nerve growth factor on glucose utilization and nucleotide content of pheochromocytoma cells (clone PC12)

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Effect of dopamine, dimethoxyphenylethylamine, papaverine, and related compounds on mitochondrial respiration and complex I activity

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Effects of various tetrahydroisoquinoline derivatives on mitochondrial respiration and the electron transfer complexes

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Presence of methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolines, derivatives of the neurotoxin isoquinoline, in parkinsonian lumbar CSF.

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Studies on the metabolism and toxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in cultures of embryonic rat mesencephalon

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Impaired oxidative decarboxylation of pyruvate in fibroblasts from patients with Parkinson's disease

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10.1016/S0006-8993(99)02272-6

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/10650131

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 May 2018

http://europepmc.org/abstract/MED/10650131

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