(Q52580057)

3 May 2018

title

T cell responses in mammalian diaphanous-related formin mDia1 knock-out mice. (English)

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3 May 2018

author name string

Kathryn M Eisenmann

1

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3 May 2018

Richard A West

2

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3 May 2018

Dagmar Hildebrand

3

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3 May 2018

Susan M Kitchen

4

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3 May 2018

Jun Peng

5

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3 May 2018

Robert Sigler

6

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3 May 2018

Jinyi Zhang

7

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3 May 2018

Katherine A Siminovitch

8

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3 May 2018

Arthur S Alberts

9

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3 May 2018

language of work or name

English

0 references

publication date

26 June 2007

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3 May 2018

Journal of Biological Chemistry

number of pages

7

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based on heuristic

inferred from page(s)

published in

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3 May 2018

volume

282

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3 May 2018

issue

34

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3 May 2018

page(s)

25152-25158

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3 May 2018

Rho GTPases: biochemistry and biology

cites work

1 reference

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RhoB regulates endosome transport by promoting actin assembly on endosomal membranes through Dia1.

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p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin

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Analysis of RhoA-binding proteins reveals an interaction domain conserved in heterotrimeric G protein beta subunits and the yeast response regulator protein Skn7

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Disruption of the Diaphanous-related formin Drf1 gene encoding mDia1 reveals a role for Drf3 as an effector for Cdc42

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Molecular details of formin-mediated actin assembly

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Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation

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A defect in hematopoietic stem cell migration explains the nonrandom X-chromosome inactivation in carriers of Wiskott-Aldrich syndrome

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Nonsyndromic Deafness DFNA1 Associated with Mutation of a Human Homolog of the Drosophila Gene diaphanous

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Identification of a carboxyl-terminal diaphanous-related formin homology protein autoregulatory domain

21 January 2018

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A human homologue of the Drosophila melanogaster diaphanous gene is disrupted in a patient with premature ovarian failure: evidence for conserved function in oogenesis and implications for human sterility

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Wiskott-Aldrich syndrome protein is required for regulatory T cell homeostasis

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The Wiskott-Aldrich syndrome protein is required for the function of CD4(+)CD25(+)Foxp3(+) regulatory T cells

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Requirement for coronin 1 in T lymphocyte trafficking and cellular homeostasis

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T cell activation and the cytoskeleton

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The Wiskott-Aldrich syndrome protein acts downstream of CD2 and the CD2AP and PSTPIP1 adaptors to promote formation of the immunological synapse

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Cytoskeletal remodeling in lymphocyte activation

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T cell receptor signaling: beyond complex complexes

21 January 2018

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Fyn and PTP-PEST-mediated regulation of Wiskott-Aldrich syndrome protein (WASp) tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation

21 January 2018

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Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

21 January 2018

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Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes

21 January 2018

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EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration

21 January 2018

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The Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing Apc and c-Src

21 January 2018

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The RhoA effector mDia is induced during T cell activation and regulates actin polymerization and cell migration in T lymphocytes

21 January 2018

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Formins regulate the actin-related protein 2/3 complex-independent polarization of the centrosome to the immunological synapse

21 January 2018

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Impaired integrin-dependent function in Wiskott-Aldrich syndrome protein-deficient murine and human neutrophils

21 January 2018

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Localized RhoA activation as a requirement for the induction of membrane ruffling

21 January 2018

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Spatiotemporal dynamics of RhoA activity in migrating cells

21 January 2018

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The Wiskott-Aldrich syndrome protein: forging the link between actin and cell activation

21 January 2018

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Direct regulation of Arp2/3 complex activity and function by the actin binding protein coronin

21 January 2018

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Cooperation between mDia1 and ROCK in Rho-induced actin reorganization

21 January 2018

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mDia mediates Rho-regulated formation and orientation of stable microtubules

21 January 2018

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The basic region of the diaphanous-autoregulatory domain (DAD) is required for autoregulatory interactions with the diaphanous-related formin inhibitory domain

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M703243200

1 reference

3 May 2018

1 reference

3 May 2018