(Q52610861)

English

Using mouse models to investigate the biological and physiological consequences of defects in the Fanconi anaemia/breast cancer DNA repair signalling pathway.

scientific article published on 9 May 2011

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scholarly article

1 reference

Europe PubMed Central

4 May 2018

http://europepmc.org/abstract/MED/21557222

Using mouse models to investigate the biological and physiological consequences of defects in the Fanconi anaemia/breast cancer DNA repair signalling pathway. (English)

1 reference

Europe PubMed Central

4 May 2018

http://europepmc.org/abstract/MED/21557222

author name string

Marc Tischkowitz

1

1 reference

Europe PubMed Central

4 May 2018

http://europepmc.org/abstract/MED/21557222

Robert Winqvist

2

1 reference

Europe PubMed Central

4 May 2018

http://europepmc.org/abstract/MED/21557222

publication date

9 May 2011

1 reference

Europe PubMed Central

4 May 2018

http://europepmc.org/abstract/MED/21557222

Journal of Pathology

1 reference

Europe PubMed Central

4 May 2018

http://europepmc.org/abstract/MED/21557222

224

1 reference

Europe PubMed Central

4 May 2018

http://europepmc.org/abstract/MED/21557222

3

1 reference

Europe PubMed Central

4 May 2018

http://europepmc.org/abstract/MED/21557222

301-305

1 reference

Europe PubMed Central

4 May 2018

http://europepmc.org/abstract/MED/21557222

Loss of p53 partially rescues embryonic development of Palb2 knockout mice but does not foster haploinsufficiency of Palb2 in tumour suppression

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

PALB2/FANCN: recombining cancer and Fanconi anemia

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

PALB2 is an integral component of the BRCA complex required for homologous recombination repair

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and BRCA2.

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Fanconi anemia and its diagnosis

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Cancer incidence in persons with Fanconi anemia.

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

The genetic and molecular basis of Fanconi anemia

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

The Fanconi anemia protein interaction network: casting a wide net.

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Mutation of the RAD51C gene in a Fanconi anemia-like disorder

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

The DNA Damage Response: Making It Safe to Play with Knives

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Expanded roles of the Fanconi anemia pathway in preserving genomic stability

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Clinical and molecular features associated with biallelic mutations in FANCD1/BRCA2.

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

A novel gene, Pog, is necessary for primordial germ cell proliferation in the mouse and underlies the germ cell deficient mutation, gcd

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia.

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Targeted disruption of exons 1 to 6 of the Fanconi Anemia group A gene leads to growth retardation, strain-specific microphthalmia, meiotic defects and primordial germ cell hypoplasia

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Inactivation of Palb2 gene leads to mesoderm differentiation defect and early embryonic lethality in mice

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Contribution of inherited mutations in the BRCA2-interacting protein PALB2 to familial breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Analysis of PALB2/FANCN-associated breast cancer families

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

A recurrent mutation in PALB2 in Finnish cancer families.

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Promoter hypermethylation of the PALB2 susceptibility gene in inherited and sporadic breast and ovarian cancer

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Accurate prediction of BRCA1 and BRCA2 heterozygous genotype using expression profiling after induced DNA damage

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Lower level of BRCA2 protein in heterozygous mutation carriers is correlated with an increase in DNA double strand breaks and an impaired DSB repair

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Mice with a targeted disruption of the Fanconi anemia homolog Fanca

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Reduced fertility and hypersensitivity to mitomycin C characterize Fancg/Xrcc9 null mice

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M.

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Fanconi anemia group A and C double-mutant mice: functional evidence for a multi-protein Fanconi anemia complex.

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Analysis of FANCB and FANCN/PALB2 Fanconi Anemia genes in BRCA1/2-negative Spanish breast cancer families

1 reference

https://api.crossref.org/works/10.1002%2FPATH.2903

21 January 2018

Identifiers

10.1002/PATH.2903

1 reference

Europe PubMed Central

4 May 2018

http://europepmc.org/abstract/MED/21557222

1 reference

Europe PubMed Central

4 May 2018

http://europepmc.org/abstract/MED/21557222

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