(Q52625208)

4 May 2018

title

Peptide-based mediated disruption of N-cadherin-LRP5/6 interaction promotes Wnt signaling and bone formation. (English)

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4 May 2018

author

Eric Hay

1

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author name string

Thibault Buczkowski

2

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Caroline Marty

3

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Sophie Da Nascimento

4

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Pascal Sonnet

5

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Pierre J Marie

6

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publication date

1 September 2012

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4 May 2018

Journal of Bone and Mineral Research

published in

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volume

27

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issue

9

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page(s)

1852-1863

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Wnt/beta-catenin signaling in development and disease

cites work

1 reference

Wnt/beta-catenin signaling: components, mechanisms, and diseases

21 January 2018

1 reference

The Wnt signaling pathway in development and disease

21 January 2018

1 reference

The many ways of Wnt in cancer

21 January 2018

1 reference

21 January 2018

1 reference

LRP5 and Wnt signaling: a union made for bone

21 January 2018

1 reference

LRP6 mutation in a family with early coronary disease and metabolic risk factors

21 January 2018

1 reference

Blockade of Wnt-1 signaling induces apoptosis in human colorectal cancer cells containing downstream mutations.

21 January 2018

1 reference

Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

21 January 2018

1 reference

Inhibition of Wnt signaling by Dishevelled PDZ peptides

21 January 2018

1 reference

Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α

21 January 2018

1 reference

Where Wnts went: the exploding field of Lrp5 and Lrp6 signaling in bone

21 January 2018

1 reference

Orally bioavailable GSK-3alpha/beta dual inhibitor increases markers of cellular differentiation in vitro and bone mass in vivo

21 January 2018

1 reference

Lrp5-independent activation of Wnt signaling by lithium chloride increases bone formation and bone mass in mice

21 January 2018

1 reference

Generation and selection of novel fully human monoclonal antibodies that neutralize Dickkopf-1 (DKK1) inhibitory function in vitro and increase bone mass in vivo

21 January 2018

1 reference

A small molecule inhibitor of the Wnt antagonist secreted frizzled-related protein-1 stimulates bone formation

21 January 2018

1 reference

Convergence of Wnt, beta-catenin, and cadherin pathways

21 January 2018

1 reference

N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/beta-catenin signaling, osteoblast function, and bone formation

21 January 2018

1 reference

Interaction between LRP5 and Frat1 mediates the activation of the Wnt canonical pathway.

21 January 2018

1 reference

N-cadherin negatively regulates osteoblast proliferation and survival by antagonizing Wnt, ERK and PI3K/Akt signalling.

21 January 2018

1 reference

Bone morphogenetic protein-2 promotes osteoblast apoptosis through a Smad-independent, protein kinase C-dependent signaling pathway

21 January 2018

1 reference

Novel LRP5 missense mutation in a patient with a high bone mass phenotype results in decreased DKK1-mediated inhibition of Wnt signaling

21 January 2018

1 reference

Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions.

21 January 2018

1 reference

Networks and hubs for the transcriptional control of osteoblastogenesis.

21 January 2018

1 reference

Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

21 January 2018

1 reference

Regulation of bone mass by Wnt signaling

21 January 2018

1 reference

Role of N-cadherin in bone formation

21 January 2018

1 reference

Cell-cell adhesion and signaling through cadherins: connecting bone cells in their microenvironment

21 January 2018

1 reference

Wnt signalling in stem cells and cancer

21 January 2018

1 reference

Wnt proteins prevent apoptosis of both uncommitted osteoblast progenitors and differentiated osteoblasts by beta-catenin-dependent and -independent signaling cascades involving Src/ERK and phosphatidylinositol 3-kinase/AKT.

21 January 2018

1 reference

Stimulation of bone formation in vitro and in rodents by statins

21 January 2018

1 reference

BMP2 signaling in bone development and repair

21 January 2018

1 reference

The cadherin cytoplasmic domain is unstructured in the absence of beta-catenin. A possible mechanism for regulating cadherin turnover

21 January 2018

1 reference

Adhesion molecule signalling: not always a sticky business.

21 January 2018

1 reference

The promise and perils of Wnt signaling through beta-catenin.

21 January 2018

1 reference

Mining the Wnt pathway for cancer therapeutics

21 January 2018

1 reference

Senescence-associated intrinsic mechanisms of osteoblast dysfunctions.

21 January 2018

1 reference

Essential requirement of BMPs-2/4 for both osteoblast and osteoclast formation in murine bone marrow cultures from adult mice: antagonism by noggin

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JBMR.1656

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4 May 2018

PubMed ID

22576936

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4 May 2018