(Q52691612)

5 May 2018

title

The evolving role of DNA inter-strand crosslinks in chemotherapy. (English)

1 reference

5 May 2018

author name string

Halley B Rycenga

series ordinal

1

1 reference

5 May 2018

David T Long

series ordinal

2

1 reference

5 May 2018

publication date

18 April 2018

1 reference

5 May 2018

Current Opinion in Pharmacology

published in

1 reference

5 May 2018

volume

41

1 reference

5 May 2018

page(s)

20-26

1 reference

5 May 2018

Fanconi Anemia Signaling and Cancer.

cites work

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2 November 2018

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RPA activates the XPF-ERCC1 endonuclease to initiate processing of DNA interstrand crosslinks.

2 November 2018

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Drugging the Cancers Addicted to DNA Repair

2 November 2018

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A role for the base excision repair enzyme NEIL3 in replication-dependent repair of interstrand DNA cross-links derived from psoralen and abasic sites

2 November 2018

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The FA/BRCA Pathway Identified as the Major Predictor of Cisplatin Response in Head and Neck Cancer by Functional Genomics

2 November 2018

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Replication-Dependent Unhooking of DNA Interstrand Cross-Links by the NEIL3 Glycosylase

2 November 2018

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Biomarkers of Response and Resistance to DNA Repair Targeted Therapies

2 November 2018

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Mitomycin C: new strategies to improve efficacy of a well-known therapy.

2 November 2018

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p97 Promotes a Conserved Mechanism of Helicase Unloading during DNA Cross-Link Repair

2 November 2018

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Cellular response to DNA interstrand crosslinks: the Fanconi anemia pathway

2 November 2018

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FANCM interacts with PCNA to promote replication traverse of DNA interstrand crosslinks.

2 November 2018

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DNA Damage Signalling and Repair Inhibitors: The Long-Sought-After Achilles' Heel of Cancer

2 November 2018

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What is the DNA repair defect underlying Fanconi anemia?

2 November 2018

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Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp.

2 November 2018

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ATR-mediated phosphorylation of FANCI regulates dormant origin firing in response to replication stress.

2 November 2018

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Interventions for vitiligo

2 November 2018

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DNA interstrand cross-link repair requires replication-fork convergence.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

Biallelic mutations in BRCA1 cause a new Fanconi anemia subtype

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

BRCA1 promotes unloading of the CMG helicase from a stalled DNA replication fork

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

XPF-ERCC1 acts in Unhooking DNA interstrand crosslinks in cooperation with FANCD2 and FANCP/SLX4

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

Cancer multidrug resistance: mechanisms involved and strategies for circumvention using a drug delivery system.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

The DNA translocase FANCM/MHF promotes replication traverse of DNA interstrand crosslinks

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

BRCA1: a missing link in the Fanconi anemia/BRCA pathway

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

NEIL1 responds and binds to psoralen-induced DNA interstrand crosslinks

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

DNA repair dysregulation from cancer driver to therapeutic target

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

Repair of cisplatin-induced DNA interstrand crosslinks by a replication-independent pathway involving transcription-coupled repair and translesion synthesis

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

Cisplatin resistance: a cellular self-defense mechanism resulting from multiple epigenetic and genetic changes

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

DNA interstrand cross-linking agents and their chemotherapeutic potential

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

Mechanism of cell death resulting from DNA interstrand cross-linking in mammalian cells.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

Mechanism of RAD51-dependent DNA interstrand cross-link repair.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

Secondary somatic mutations restoring BRCA1/2 predict chemotherapy resistance in hereditary ovarian carcinomas.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

DNA interstrand crosslink repair and cancer

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

DNA interstrand crosslink repair in mammalian cells: step by step

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

Repair of laser-localized DNA interstrand cross-links in G1 phase mammalian cells

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

The human oxidative DNA glycosylase NEIL1 excises psoralen-induced interstrand DNA cross-links in a three-stranded DNA structure

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

A model for initial DNA lesion recognition by NER and MMR based on local conformational flexibility

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

DNA damage-processing pathways involved in the eukaryotic cellular response to anticancer DNA cross-linking drugs

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

Repair of DNA interstrand cross-links

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

DNA replication is required To elicit cellular responses to psoralen-induced DNA interstrand cross-links.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

Mitomycin C: small, fast and deadly (but very selective)

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

Solution structures of psoralen monoadducted and cross-linked DNA oligomers by NMR spectroscopy and restrained molecular dynamics

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

The formation, isolation and characterization of DNA adducts produced by anticancer platinum complexes

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

Mitomycin C: mechanism of action, usefulness and limitations

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

Synthesis and characterization of new psoralen derivatives with superior photoreactivity with DNA and RNA.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6108900

Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA

2 November 2018

1 reference

12 December 2020

Phased psoralen cross-links do not bend the DNA double helix

1 reference

12 December 2020

Quantitative aspects of the formation and loss of DNA interstrand crosslinks in Chinese hamster cells following treatment with cis-diamminedichloroplatinum(II) (cisplatin) II. Comparison of results from alkaline elution, DNA renaturation and DNA sedi

1 reference

12 December 2020

Recognition of DNA interstrand cross-links of cis-diamminedichloroplatinum(II) and its trans isomer by DNA-binding proteins

1 reference

12 December 2020

Bending of DNA by the mitomycin C-induced, GpG intrastrand cross-link

1 reference

12 December 2020

Detection of mitomycin C-DNA adducts in vivo by 32P-postlabeling: time course for formation and removal of adducts and biochemical modulation

1 reference

12 December 2020

DNA Cross-Linking Agents as Antitumor Drugs

1 reference

12 December 2020

Mitomycin C from birth to adulthood

1 reference

12 December 2020

10.1016/J.COPH.2018.04.004

Identifiers

DOI

1 reference

5 May 2018

PMC publication ID

6108900

0 references

1 reference

5 May 2018