(Q52695415)

5 May 2018

review article

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title

Remodeling the clock: coactivators and signal transduction in the circadian clockworks. (English)

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5 May 2018

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Frank Weber

1

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5 May 2018

publication date

4 December 2008

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5 May 2018

published in

The Science of Nature

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5 May 2018

volume

96

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5 May 2018

issue

3

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5 May 2018

page(s)

321-337

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5 May 2018

https://scigraph.springernature.com/pub.10.1007/s00114-008-0474-9

exact match

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cites work

Regulating a circadian clock's period, phase and amplitude by phosphorylation: insights from Drosophila

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00114-008-0474-9

The mammalian circadian timing system: from gene expression to physiology

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00114-008-0474-9

PER and TIM inhibit the DNA binding activity of a Drosophila CLOCK-CYC/dBMAL1 heterodimer without disrupting formation of the heterodimer: a basis for circadian transcription

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00114-008-0474-9

A role for the segment polarity gene shaggy/GSK-3 in the Drosophila circadian clock

21 January 2018

1 reference

12 December 2020

BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system

1 reference

12 December 2020

Time zones: a comparative genetics of circadian clocks

1 reference

12 December 2020

Why life oscillates--from a topographical towards a functional chronobiology.

1 reference

12 December 2020

Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300.

1 reference

12 December 2020

NMDA receptor antagonists block the effects of light on circadian behavior in the mouse

1 reference

12 December 2020

Molecular bases of circadian rhythms

1 reference

12 December 2020

Waking experience affects sleep need in Drosophila

1 reference

12 December 2020

Interlocked feedback loops of the circadian clock of Neurospora crassa.

1 reference

12 December 2020

Dimerization and nuclear entry of mPER proteins in mammalian cells

1 reference

12 December 2020

Melanopsin-containing retinal ganglion cells: architecture, projections, and intrinsic photosensitivity

1 reference

12 December 2020

Post-translational regulation of the Drosophila circadian clock requires protein phosphatase 1 (PP1)

1 reference

12 December 2020

SCN outputs and the hypothalamic balance of life

1 reference

12 December 2020

Drosophila CLOCK is constitutively expressed in circadian oscillator and non-oscillator cells

1 reference

12 December 2020

Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilon

1 reference

12 December 2020

Protein phosphatase 1 regulates the stability of the circadian protein PER2.

1 reference

12 December 2020

Second messenger and Ras/MAPK signalling pathways regulate CLOCK/CYCLE-dependent transcription.

1 reference

12 December 2020

PER-dependent rhythms in CLK phosphorylation and E-box binding regulate circadian transcription

1 reference

12 December 2020

Regularly scheduled voluntary exercise synchronizes the mouse circadian clock

1 reference

12 December 2020

CBP/p300 in cell growth, transformation, and development

1 reference

12 December 2020

Functional consequences of a CKIdelta mutation causing familial advanced sleep phase syndrome

1 reference

12 December 2020

A GABAergic mechanism is necessary for coupling dissociable ventral and dorsal regional oscillators within the circadian clock

1 reference

12 December 2020

Novel insights into the regulation of the timeless protein.

1 reference

12 December 2020

A functional genomics strategy reveals clockwork orange as a transcriptional regulator in the Drosophila circadian clock

1 reference

12 December 2020

PDF receptor signaling in Drosophila contributes to both circadian and geotactic behaviors

1 reference

12 December 2020

A screen for secreted factors of the suprachiasmatic nucleus

1 reference

12 December 2020

Resetting the biological clock: mediation of nocturnal CREB phosphorylation via light, glutamate, and nitric oxide

1 reference

12 December 2020

Posttranslational regulation of Drosophila PERIOD protein by protein phosphatase 2A.

1 reference

12 December 2020

Transactivation mechanisms of mouse clock transcription factors, mClock and mArnt3.

1 reference

12 December 2020

Veela defines a molecular link between Cryptochrome and Timeless in the light-input pathway to Drosophila's circadian clock

1 reference

12 December 2020

Involvement of the MAP kinase cascade in resetting of the mammalian circadian clock

1 reference

12 December 2020

Phosphorylation of period is influenced by cycling physical associations of double-time, period, and timeless in the Drosophila clock.

1 reference

12 December 2020

Circadian cycling of the mouse liver transcriptome, as revealed by cDNA microarray, is driven by the suprachiasmatic nucleus.

1 reference

12 December 2020

The Drosophila dCREB2 gene affects the circadian clock.

1 reference

12 December 2020

Minireview: The neuroendocrinology of the suprachiasmatic nucleus as a conductor of body time in mammals.

1 reference

12 December 2020

A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila

1 reference

12 December 2020

vrille, Pdp1, and dClock form a second feedback loop in the Drosophila circadian clock

1 reference

12 December 2020

Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions

1 reference

12 December 2020

Histone acetyltransferase-dependent chromatin remodeling and the vascular clock

1 reference

12 December 2020

Post-translational modifications regulate the ticking of the circadian clock.

1 reference

12 December 2020

E2F inhibits transcriptional activation by the retinoic acid receptor

1 reference

12 December 2020

The circadian clock of fruit flies is blind after elimination of all known photoreceptors.

1 reference

12 December 2020

Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus

1 reference

12 December 2020

Vasoactive intestinal peptide and the mammalian circadian system

1 reference

12 December 2020

Rhythmic E-box binding by CLK-CYC controls daily cycles in per and tim transcription and chromatin modifications

1 reference

12 December 2020

Circadian rhythms from multiple oscillators: lessons from diverse organisms

1 reference

12 December 2020

Bimodal regulation of mPeriod promoters by CREB-dependent signaling and CLOCK/BMAL1 activity

1 reference

12 December 2020

Circadian regulator CLOCK is a histone acetyltransferase

1 reference

12 December 2020

A TIMELESS-independent function for PERIOD proteins in the Drosophila clock

1 reference

12 December 2020

Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock

1 reference

12 December 2020

Light and circadian rhythmicity regulate MAP kinase activation in the suprachiasmatic nuclei.

1 reference

12 December 2020

A role for glycogen synthase kinase-3beta in the mammalian circadian clock

1 reference

12 December 2020

PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues

1 reference

12 December 2020

Diurnal modulation of pacemaker potentials and calcium current in the mammalian circadian clock.

1 reference

12 December 2020

Regulation of inhibitory synaptic transmission by vasoactive intestinal peptide (VIP) in the mouse suprachiasmatic nucleus

1 reference

12 December 2020

Closing the circadian loop: CLOCK-induced transcription of its own inhibitors per and tim.

1 reference

12 December 2020

The VPAC(2) receptor is essential for circadian function in the mouse suprachiasmatic nuclei

1 reference

12 December 2020

Probing the relative importance of molecular oscillations in the circadian clock

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12 December 2020

1 reference

12 December 2020

Hofbauer-Buchner eyelet affects circadian photosensitivity and coordinates TIM and PER expression in Drosophila clock neurons.

1 reference

12 December 2020

Sequential nuclear accumulation of the clock proteins period and timeless in the pacemaker neurons of Drosophila melanogaster.

1 reference

12 December 2020

Activating PER repressor through a DBT-directed phosphorylation switch

1 reference

12 December 2020

Functional analysis of circadian pacemaker neurons in Drosophila melanogaster.

1 reference

12 December 2020

The circadian timekeeping system of Drosophila.

1 reference

12 December 2020

The circadian regulatory proteins BMAL1 and cryptochromes are substrates of casein kinase Iepsilon

1 reference

12 December 2020

Clock Mutants of Drosophila melanogaster

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12 December 2020

Electrical silencing of PDF neurons advances the phase of non-PDF clock neurons in Drosophila

1 reference

12 December 2020

Rhythmic histone acetylation underlies transcription in the mammalian circadian clock

1 reference

12 December 2020

Pharmacological imposition of sleep slows cognitive decline and reverses dysregulation of circadian gene expression in a transgenic mouse model of Huntington's disease.

1 reference

12 December 2020

A role for the proteasome in the light response of the timeless clock protein.

1 reference

12 December 2020

The cryb mutation identifies cryptochrome as a circadian photoreceptor in Drosophila.

1 reference

12 December 2020

Mitogen-activated protein kinase phosphorylates and negatively regulates basic helix-loop-helix-PAS transcription factor BMAL1.

1 reference

12 December 2020

cGMP induces phase shifts of a mammalian circadian pacemaker at night, in antiphase to cAMP effects

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12 December 2020

Morning and evening peaks of activity rely on different clock neurons of the Drosophila brain

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12 December 2020

The phospho-occupancy of an atypical SLIMB-binding site on PERIOD that is phosphorylated by DOUBLETIME controls the pace of the clock.

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12 December 2020

Circadian proteins in the regulation of cell cycle and genotoxic stress responses.

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12 December 2020

Reconstitution of circadian oscillation of cyanobacterial KaiC phosphorylation in vitro

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12 December 2020

A role for CK2 in the Drosophila circadian oscillator

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12 December 2020

Posttranslational mechanisms regulate the mammalian circadian clock

1 reference

12 December 2020

Electrical silencing of Drosophila pacemaker neurons stops the free-running circadian clock.

1 reference

12 December 2020

Circadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression

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12 December 2020

Altered circadian pacemaker functions and cyclic AMP rhythms in the Drosophila learning mutant dunce

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12 December 2020

Localization of calcitonin receptor mRNA in the mouse brain: coexistence with serotonin transporter mRNA

1 reference

12 December 2020

The molecular clock mediates leptin-regulated bone formation.

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12 December 2020

Circadian orchestration of the hepatic proteome

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12 December 2020

Balance between DBT/CKIepsilon kinase and protein phosphatase activities regulate phosphorylation and stability of Drosophila CLOCK protein

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12 December 2020

Resetting the circadian clock by social experience in Drosophila melanogaster.

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12 December 2020

Circadian transcription depends on limiting amounts of the transcription co-activator nejire/CBP.

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12 December 2020

Independent photoreceptive circadian clocks throughout Drosophila

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12 December 2020

double-time is a novel Drosophila clock gene that regulates PERIOD protein accumulation

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12 December 2020

Functional role of CREB-binding protein in the circadian clock system of Drosophila melanogaster

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12 December 2020

Short-period mutations of per affect a double-time-dependent step in the Drosophila circadian clock.

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12 December 2020

Organization of the Drosophila circadian control circuit

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12 December 2020

Coupled oscillators control morning and evening locomotor behaviour of Drosophila

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12 December 2020

Central administration of transforming growth factor-alpha and neuregulin-1 suppress active behaviors and cause weight loss in hamsters

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12 December 2020

Loss of circadian clock function decreases reproductive fitness in males of Drosophila melanogaster

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12 December 2020

Control mechanism of the circadian clock for timing of cell division in vivo.

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12 December 2020

A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors

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12 December 2020

Development and morphology of the clock-gene-expressing lateral neurons of Drosophila melanogaster.

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12 December 2020

The Drosophila CLOCK protein undergoes daily rhythms in abundance, phosphorylation, and interactions with the PER-TIM complex.

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12 December 2020

Dec1 and Dec2 are regulators of the mammalian molecular clock

1 reference

12 December 2020

The clockwork orange Drosophila protein functions as both an activator and a repressor of clock gene expression.

1 reference

12 December 2020

The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo

1 reference

12 December 2020

PERIOD1-associated proteins modulate the negative limb of the mammalian circadian oscillator

1 reference

12 December 2020

Role of melanopsin in circadian responses to light

1 reference

12 December 2020

Coordinated transcription of key pathways in the mouse by the circadian clock

1 reference

12 December 2020

Cellular oscillators: rhythmic gene expression and metabolism

1 reference

12 December 2020

Circadian oscillators of Drosophila and mammals.

1 reference

12 December 2020

A PERIOD inhibitor buffer introduces a delay mechanism for CLK/CYC-activated transcription.

1 reference

12 December 2020

A role for cardiotrophin-like cytokine in the circadian control of mammalian locomotor activity.

1 reference

12 December 2020

The neuropeptide pigment-dispersing factor coordinates pacemaker interactions in the Drosophila circadian system.

1 reference

12 December 2020

Stopping time: the genetics of fly and mouse circadian clocks.

1 reference

12 December 2020

PER-TIM interactions in living Drosophila cells: an interval timer for the circadian clock

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12 December 2020

Role for Slimb in the degradation of Drosophila Period protein phosphorylated by Doubletime.

1 reference

12 December 2020

PDP1epsilon functions downstream of the circadian oscillator to mediate behavioral rhythms

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12 December 2020

Cycling vrille expression is required for a functional Drosophila clock

1 reference

12 December 2020

Cryptochrome, Compound Eyes, Hofbauer-Buchner Eyelets, and Ocelli Play Different Roles in the Entrainment and Masking Pathway of the Locomotor Activity Rhythm in the Fruit Fly Drosophila Melanogaster

1 reference

12 December 2020

A circadian output in Drosophila mediated by neurofibromatosis-1 and Ras/MAPK.

1 reference

12 December 2020

A resetting signal between Drosophila pacemakers synchronizes morning and evening activity

1 reference

12 December 2020

The F-box protein slimb controls the levels of clock proteins period and timeless

1 reference

12 December 2020

Clockwork Orange is a transcriptional repressor and a new Drosophila circadian pacemaker component

1 reference

12 December 2020

Interacting molecular loops in the mammalian circadian clock

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12 December 2020

Melanopsin (Opn4) requirement for normal light-induced circadian phase shifting

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12 December 2020

SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins

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12 December 2020

Glutamate blocks serotonergic phase advances of the mammalian circadian pacemaker through AMPA and NMDA receptors.

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12 December 2020

Drosophila GPCR Han is a receptor for the circadian clock neuropeptide PDF.

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12 December 2020

Intracellular Ca2+ regulates free-running circadian clock oscillation in vivo.

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12 December 2020

The double-time protein kinase regulates the subcellular localization of the Drosophila clock protein period

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12 December 2020

Neurobiology of the fruit fly's circadian clock.

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12 December 2020

A role for casein kinase 2alpha in the Drosophila circadian clock

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12 December 2020

The after-hours mutant reveals a role for Fbxl3 in determining mammalian circadian period

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12 December 2020

Clockwork orange encodes a transcriptional repressor important for circadian-clock amplitude in Drosophila

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12 December 2020

Chronodisruption and cancer

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12 December 2020

The Drosophila circadian network is a seasonal timer

1 reference

12 December 2020

cAMP-dependent signaling as a core component of the mammalian circadian pacemaker

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12 December 2020

CREB in the mouse SCN: a molecular interface coding the phase-adjusting stimuli light, glutamate, PACAP, and melatonin for clockwork access.

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12 December 2020

Circadian clock control by SUMOylation of BMAL1.

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12 December 2020

Dual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of the CLOCK/BMAL1 complex

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12 December 2020

A G protein-coupled receptor, groom-of-PDF, is required for PDF neuron action in circadian behavior

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12 December 2020

Light-dependent sequestration of TIMELESS by CRYPTOCHROME

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12 December 2020

Multiple amidated neuropeptides are required for normal circadian locomotor rhythms in Drosophila.

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12 December 2020

A functional genomics strategy reveals Rora as a component of the mammalian circadian clock

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12 December 2020

Stress response genes protect against lethal effects of sleep deprivation in Drosophila

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12 December 2020

Nucleocytoplasmic shuttling and mCRY-dependent inhibition of ubiquitylation of the mPER2 clock protein

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12 December 2020

Circadian regulation of gene expression systems in the Drosophila head

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12 December 2020

Entrainment of the circadian clock in the liver by feeding

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12 December 2020

JETLAG resets the Drosophila circadian clock by promoting light-induced degradation of TIMELESS.

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12 December 2020

Microarray analysis and organization of circadian gene expression in Drosophila

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12 December 2020

Circadian transcription contributes to core period determination in Drosophila

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12 December 2020

Drosophila CLOCK protein is under posttranscriptional control and influences light-induced activity.

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12 December 2020

The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator

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12 December 2020

Resetting the biological clock: mediation of nocturnal circadian shifts by glutamate and NO

1 reference

12 December 2020

Circadian clocks: regulators of endocrine and metabolic rhythms

1 reference

12 December 2020

Widespread receptivity to neuropeptide PDF throughout the neuronal circadian clock network of Drosophila revealed by real-time cyclic AMP imaging

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12 December 2020

Vasoactive intestinal polypeptide induces per1 and per2 gene expression in the rat suprachiasmatic nucleus late at night.

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12 December 2020

The nuclear receptors Rev-erbs and RORs integrate circadian rhythms and metabolism.

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12 December 2020

Ser-557-phosphorylated mCRY2 is degraded upon synergistic phosphorylation by glycogen synthase kinase-3 beta.

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12 December 2020

10.1007/S00114-008-0474-9

Identifiers

DOI

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5 May 2018

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5 May 2018