(Q52704996)

6 May 2018

title

The amplification loop of the complement pathways. (English)

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6 May 2018

author name string

Peter J Lachmann

series ordinal

1

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6 May 2018

publication date

1 December 2009

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6 May 2018

published in

Advances in Immunology

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6 May 2018

volume

104

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6 May 2018

page(s)

115-149

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6 May 2018

Studies in vivo and in vitro on an abnormality in the metabolism of C3 in a patient with increased susceptibility to infection

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Antimalarial responses in Anopheles gambiae: from a complement-like protein to a complement-like pathway

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Homozygous hereditary C3 deficiency due to a partial gene deletion

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7 January 2021

Fluid-phase interaction of C1 inhibitor (C1 Inh) and the subcomponents C1r and C1s of the first component of complement, C1

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7 January 2021

Transfer of C3 nephritic factor from mother to fetus. Is C3 nephritic factor IgG?

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Genetic control of survival in epidemics

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7 January 2021

Targeting age-related macular degeneration with Alzheimer's disease based immunotherapies: anti-amyloid-beta antibody attenuates pathologies in an age-related macular degeneration mouse model

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7 January 2021

The phylogeny and evolution of the thioester bond-containing proteins C3, C4 and alpha 2-macroglobulin.

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7 January 2021

Atypical haemolytic uraemic syndrome and mutations in complement regulator genes

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7 January 2021

Fundus changes in (type II) mesangiocapillary glomerulonephritis simulating drusen: a histopathological report

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Fundus changes in mesangiocapillary glomerulonephritis type II: clinical and fluorescein angiographic findings

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7 January 2021

Resolution and analysis of 'native' and 'activated' properdin

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7 January 2021

Properdin: binding to C3b and stabilization of the C3b-dependent C3 convertase

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7 January 2021

Activation of the alternative complement pathway with rabbit erythrocytes by circumvention of the regulatory action of endogenous control proteins

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7 January 2021

Molecular analysis of C3 allotypes in patients with nephritic factor

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7 January 2021

The development of atypical haemolytic-uraemic syndrome is influenced by susceptibility factors in factor H and membrane cofactor protein: evidence from two independent cohorts

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7 January 2021

Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome

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7 January 2021

The alternative complement pathway revisited

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7 January 2021

The physiological breakdown of the third component of human complement

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7 January 2021

Novel cleavage products of the third component of human complement

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7 January 2021

Complete and partial deficiencies of complement factor D in a Dutch family

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7 January 2021

Hereditary porcine membranoproliferative glomerulonephritis type II is caused by factor H deficiency

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7 January 2021

Eradication of porcine factor H deficiency in Norway

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7 January 2021

Structures of complement component C3 provide insights into the function and evolution of immunity

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7 January 2021

Effects of Granulocyte Neutral Proteases on Complement Components

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7 January 2021

Mutations in complement factor I predispose to development of atypical hemolytic uremic syndrome

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7 January 2021

Characterization of mutations in complement factor I (CFI) associated with hemolytic uremic syndrome

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7 January 2021

Properdin: New roles in pattern recognition and target clearance.

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7 January 2021

Structure and function of recombinant cobra venom factor

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7 January 2021

Association between coronary heart disease and the C3F-gene in essential hypertension

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7 January 2021

The purification of specific antibody as F(ab')2 by the pepsin digestion of antigen-antibody precipitates, and its application to immunoglobulin and complement antigens.

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7 January 2021

Complement before molecular biology

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7 January 2021

Constitutive expression of a complement-like protein in toll and JAK gain-of-function mutants of Drosophila

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7 January 2021

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

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7 January 2021

The internal thioester and the covalent binding properties of the complement proteins C3 and C4

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7 January 2021

Interaction between the third complement protein and cell surface macromolecules

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7 January 2021

Atypical hemolytic uremic syndrome associated with complement factor H autoantibodies and CFHR1/CFHR3 deficiency

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https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

Conserved role of a complement-like protein in phagocytosis revealed by dsRNA knockout in cultured cells of the mosquito, Anopheles gambiae.

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7 January 2021

COMPONENTS OF GUINEA PIG COMPLEMENT. II. SEPARATION OF SERUM FRACTIONS ESSENTIAL FOR IMMUNE HEMOLYSIS

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7 January 2021

Complement-mediated adipocyte lysis by nephritic factor sera

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7 January 2021

Abrogation of the alternative complement pathway by targeted deletion of murine factor B

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7 January 2021

Activation of the classical complement pathway by mannose-binding protein in association with a novel C1s-like serine protease

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7 January 2021

A new complement-mediated cytolytic mechanism--the C1-bypass activation pathway

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7 January 2021

Functional basis of protection against age-related macular degeneration conferred by a common polymorphism in complement factor B

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7 January 2021

C3 proactivator convertase and its mode of action

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7 January 2021

Isolation and characterization of two beta1-glycoproteins of human serum

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7 January 2021

Two cDNAs from the purple sea urchin, Strongylocentrotus purpuratus, encoding mosaic proteins with domains found in factor H, factor I, and complement components C6 and C7.

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7 January 2021

Methods for the separation, purification and measurement of nine components of hemolytic complement in guinea-pig serum

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7 January 2021

The eighth component of human complement: evidence that it is an oligomeric serum protein assembled from products of three different genes.

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7 January 2021

Formation of the initial C3 convertase of the alternative complement pathway. Acquisition of C3b-like activities by spontaneous hydrolysis of the putative thioester in native C3

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7 January 2021

Clustering of missense mutations in the C-terminal region of factor H in atypical hemolytic uremic syndrome.

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7 January 2021

The properdin system and immunity. I. Demonstration and isolation of a new serum protein, properdin, and its role in immune phenomena

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https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

Factor H mutations in hemolytic uremic syndrome cluster in exons 18-20, a domain important for host cell recognition

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

Inherited complement regulatory protein deficiency predisposes to human disease in acute injury and chronic inflammatory statesthe examples of vascular damage in atypical hemolytic uremic syndrome and debris accumulation in age-related macular degen

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome

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https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

Adipsin and complement factor D activity: an immune-related defect in obesity

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7 January 2021

Identification of a C3bi-specific membrane complement receptor that is expressed on lymphocytes, monocytes, neutrophils, and erythrocytes.

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7 January 2021

Therapeutic intervention with complement and beta-glucan in cancer

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7 January 2021

Genetic markers and biomarkers for age-related macular degeneration

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https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

Complement deficiency states and infection: epidemiology, pathogenesis and consequences of neisserial and other infections in an immune deficiency

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https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

Structural and functional characterization of factor H mutations associated with atypical hemolytic uremic syndrome

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https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

Alternative pathway of complement: demonstration and characterization of initiating factor and its properdin-independent function

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https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

The mannan-binding lectin-associated serine proteases (MASPs) and MAp19: four components of the lectin pathway activation complex encoded by two genes

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7 January 2021

Lysis of measles virus-infected cells by the purified cytolytic alternative complement pathway and antibody

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7 January 2021

Targeting anticomplement agents

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7 January 2021

The ancestral complement system in sea urchins

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7 January 2021

Association between the C3F gene and atherosclerotic vascular diseases

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https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

C3 Polymorphism in Relation to Age

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https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

Protective effect of complement factor B and complement component 2 variants in age-related macular degeneration

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https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

Serum C'3 lytic system in patients with glomerulonephritis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

Deficient alternative complement pathway activation due to factor D deficiency by 2 novel mutations in the complement factor D gene in a family with meningococcal infections

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https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

IgG3 Levels in Patients with Chronic Membranoproliferative Glomerulonephritis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

A serum factor in chronic hypocomplementemic hephritis distinct from immunoglobulins and activating the alternate pathway of complement

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

Study of the optimal reaction conditions for assay of the mouse alternative complement pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

Structure and function of cobra venom factor, the complement-activating protein in cobra venom.

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https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

Humanized cobra venom factor: experimental therapeutics for targeted complement activation and complement depletion

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

Interactions between mannose-binding lectin and MASPs during complement activation by the lectin pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

Altered function of factor I caused by amyloid beta: implication for pathogenesis of age-related macular degeneration from Drusen

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

Amyloid-beta up-regulates complement factor B in retinal pigment epithelial cells through cytokines released from recruited macrophages/microglia: Another mechanism of complement activation in age-related macular degeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

Modulation of the alternative complement pathways by beta 1 H globulin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

Complement C3 variant and the risk of age-related macular degeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

The potential role of amyloid beta in the pathogenesis of age-related macular degeneration

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https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

Association of complement factor H Y402H gene polymorphism with Alzheimer's disease

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7 January 2021

Lysis via the lectin pathway of complement activation: minireview and lectin pathway enhancement of endotoxin-initiated hemolysis

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https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

Restoration by purified C3b inactivator of complement-mediated function in vivo in a patient with C3b inactivator deficiency

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https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

Homozygous deficiency of C3 in a patient with repeated infections

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https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

Specificity of membrane complement receptor type three (CR3) for beta-glucans

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https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2904004-2

7 January 2021

10.1016/S0065-2776(08)04004-2

Identifiers

DOI

1 reference

6 May 2018

PubMed ID

20457117

1 reference

6 May 2018