(Q52862467)

9 May 2018

title

Biased VH gene expression in murine CD5 B cells results from age-dependent cellular selection. (English)

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9 May 2018

author

Véronique Thomas-Vaslin

4

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9 May 2018

author name string

Andrade L

1

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9 May 2018

Huetz F

2

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9 May 2018

Poncet P

3

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9 May 2018

Goodhardt M

5

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9 May 2018

Coutinho A

6

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9 May 2018

language of work or name

English

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publication date

1 September 1991

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9 May 2018

European Journal of Immunology

published in

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9 May 2018

volume

21

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9 May 2018

issue

9

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9 May 2018

page(s)

2017-2023

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9 May 2018

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The peritoneal Ly-1 (CD5) B cell repertoire is unique among murine B cell repertoires

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A member of a new VH gene family encodes antibromelinized mouse red blood cell autoantibodies

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All VH11 genes expressed in peritoneal lymphocytes encode anti-bromelain-treated mouse red blood cell autoantibodies but other VH gene families contribute to this specificity

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VH gene family utilization in colonies derived from B and pre-B cells detected by the RNA colony blot assay

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Multiple VH gene segments encode murine antistreptococcal antibodies

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High connectivity, natural antibodies preferentially use 7183 and QUPC 52 VH families

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Expression of antibody V-regions is genetically and developmentally controlled and modulated by the B lymphocyte environment

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7 January 2021

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7 January 2021

Biased expression of JH-proximal VH genes occurs in the newly generated repertoire of neonatal and adult mice

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7 January 2021

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7 January 2021

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7 January 2021

Normal mouse peritoneum contains a large population of Ly-1+ (CD5) B cells that recognize phosphatidyl choline. Relationship to cells that secrete hemolytic antibody specific for autologous erythrocytes

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7 January 2021

Stochastic pairing of heavy-chain and kappa light-chain variable gene families occurs in polyclonally activated B cells

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7 January 2021

Cellular basis for the age-associated increase in autoimmune reactions

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7 January 2021

Identifiers

DOI

10.1002/EJI.1830210908

1 reference

9 May 2018

1 reference

9 May 2018