(Q52895804)

English

Very early/early relapses of acute lymphoblastic leukemia show unexpected changes of clonal markers and high heterogeneity in response to initial and relapse treatment.

scientific article published on 6 May 2011

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scholarly article

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30 January 2020

Very early/early relapses of acute lymphoblastic leukemia show unexpected changes of clonal markers and high heterogeneity in response to initial and relapse treatment (English)

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30 January 2020

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lymphoblastic leukemia

1 reference

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Renate Kirschner-Schwabe

7

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30 January 2020

author name string

C Eckert

1

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30 January 2020

T Flohr

2

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30 January 2020

R Koehler

3

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30 January 2020

N Hagedorn

4

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30 January 2020

A Moericke

5

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30 January 2020

M Stanulla

6

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30 January 2020

G Cario

8

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30 January 2020

Av Stackelberg

9

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30 January 2020

C R Bartram

10

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30 January 2020

G Henze

11

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30 January 2020

M Schrappe

12

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30 January 2020

A Schrauder

13

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30 January 2020

publication date

6 May 2011

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30 January 2020

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30 January 2020

25

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30 January 2020

8

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30 January 2020

1305-1313

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30 January 2020

https://scigraph.springernature.com/pub.10.1038/leu.2011.89

0 references

Prognostic value of minimal residual disease in acute lymphoblastic leukaemia in childhood.

1 reference

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Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leu

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Molecular monitoring of residual disease using antigen receptor genes in childhood acute lymphoblastic leukaemia.

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21 January 2018

Clonal variation of the immunogenotype in relapsed ETV6/RUNX1-positive acute lymphoblastic leukemia indicates subclone formation during early stages of leukemia development

1 reference

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Clonal diversity of Ig and T-cell receptor gene rearrangements in childhood B-precursor acute lymphoblastic leukaemia.

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Late relapses evolve from slow-responding subclones in t(12;21)-positive acute lymphoblastic leukemia: evidence for the persistence of a preleukemic clone.

1 reference

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21 January 2018

Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia.

1 reference

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21 January 2018

Bone-marrow relapse in paediatric acute lymphoblastic leukaemia

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Mechanism of relapse in pediatric acute lymphoblastic leukemia.

1 reference

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Relapse in childhood acute lymphoblastic leukemia is associated with a decrease of the Bax/Bcl-2 ratio and loss of spontaneous caspase-3 processing in vivo

1 reference

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21 January 2018

Genome-wide copy number profiling reveals molecular evolution from diagnosis to relapse in childhood acute lymphoblastic leukemia

1 reference

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21 January 2018

Submicroscopic bone marrow involvement in isolated extramedullary relapses in childhood acute lymphoblastic leukemia: a more precise definition of "isolated" and its possible clinical implications, a collaborative study of the Resistant Disease Comm

1 reference

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21 January 2018

Risk-adapted stratification and treatment of childhood acute lymphoblastic leukaemia

1 reference

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21 January 2018

Vdelta2-Jalpha rearrangements are frequent in precursor-B-acute lymphoblastic leukemia but rare in normal lymphoid cells.

1 reference

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21 January 2018

Determining the repertoire of IGH gene rearrangements to develop molecular markers for minimal residual disease in B-lineage acute lymphoblastic leukemia.

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Cancer stem cells: back to Darwin?

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Childhood secondary ALL after ALL treatment.

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New insights to the MLL recombinome of acute leukemias

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Cluster analysis of genomic ETV6-RUNX1 (TEL-AML1) fusion sites in childhood acute lymphoblastic leukemia.

1 reference

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21 January 2018

Prognostic value of minimal residual disease in relapsed childhood acute lymphoblastic leukaemia

1 reference

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7 January 2021

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Sequence analysis of clonal immunoglobulin and T-cell receptor gene rearrangements in children with acute lymphoblastic leukemia at diagnosis and at relapse: implications for pathogenesis and for the clinical utility of PCR-based methods of minimal r

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.89

7 January 2021

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inferred from DOI database lookup

Gene rearrangements as markers of clonal variation and minimal residual disease in acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.89

7 January 2021

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inferred from DOI database lookup

Clonality profile in relapsed precursor-B-ALL children by GeneScan and sequencing analyses. Consequences on minimal residual disease monitoring

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.89

7 January 2021

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Comparative analysis of T-cell receptor gene rearrangements at diagnosis and relapse of T-cell acute lymphoblastic leukemia (T-ALL) shows high stability of clonal markers for monitoring of minimal residual disease and reveals the occurrence of secon

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.89

7 January 2021

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Comparative analysis of Ig and TCR gene rearrangements at diagnosis and at relapse of childhood precursor-B-ALL provides improved strategies for selection of stable PCR targets for monitoring of minimal residual disease

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.89

7 January 2021

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TCRB gene rearrangements in childhood and adult precursor-B-ALL: frequency, applicability as MRD-PCR target, and stability between diagnosis and relapse

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Origins of "late" relapse in childhood acute lymphoblastic leukemia with TEL-AML1 fusion genes

1 reference

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7 January 2021

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TEL deletion analysis supports a novel view of relapse in childhood acute lymphoblastic leukemia

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https://api.crossref.org/works/10.1038%2FLEU.2011.89

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Molecular determinants of treatment response in acute lymphoblastic leukemia

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Optimization of PCR-based minimal residual disease diagnostics for childhood acute lymphoblastic leukemia in a multi-center setting.

1 reference

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Multiplex PCR for simultaneous detection of the most frequent T cell receptor-delta gene rearrangements in childhood ALL

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Heteroduplex PCR analysis of rearranged T cell receptor genes for clonality assessment in suspect T cell proliferations

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Analysis of minimal residual disease by Ig/TCR gene rearrangements: guidelines for interpretation of real-time quantitative PCR data.

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Identifiers

10.1038/LEU.2011.89

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21546902%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21546902%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

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