(Q52900321)

9 May 2018

title

Does base composition help predispose the complementarity-determining regions of antibodies to hypermutation? (English)

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9 May 2018

author name string

Padlan EA

series ordinal

1

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9 May 2018

publication date

1 August 1997

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9 May 2018

published in

Molecular Immunology

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9 May 2018

volume

34

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9 May 2018

issue

11

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9 May 2018

page(s)

765-770

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9 May 2018

The dynamic nature of the antibody repertoire

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Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes

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Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

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The CDR1 sequences of a major proportion of human germline Ig VH genes are inherently susceptible to amino acid replacement

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A directory of human germ-line V kappa segments reveals a strong bias in their usage

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The targeting of somatic hypermutation

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Pecularities of immunoglobulin gene structures as a basis for somatic mutation emergence

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Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues

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Quantum mechanical study of bases interactions in various associates in atomic dipole approximation

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The human cord blood antibody repertoire. Frequent usage of the VH7 gene family

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Somatic hypermutation of immunoglobulin genes is linked to transcription initiation

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Hypermutation generating the sheep immunoglobulin repertoire is an antigen-independent process

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Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis

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Somatic hypermutagenesis in immunoglobulin genes. I. Correlation between somatic mutations and repeats. Somatic mutation properties and clonal selection

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Somatic mutation of immunoglobulin light-chain variable-region genes.

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Somatic hypermutation of immunoglobulin kappa may depend on sequences 3' of C kappa and occurs on passenger transgenes.

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The mechanism of somatic hypermutation studied with transgenic and transfected target genes

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Codon bias targets mutation.

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Somatic hypermutation of Ig genes in patients with xeroderma pigmentosum (XP-D)

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Variability in the Lambda Light Chain Sequences of Mouse Antibody

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Accumulation of somatic mutants in the B cell compartment after primary immunization with a T cell-dependent antigen

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Sequence and evolution of the human germline V lambda repertoire

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Targeting of non-Ig sequences in place of the V segment by somatic hypermutation.

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Identifiers

DOI

1 reference

9 May 2018

1 reference

9 May 2018