(Q52936904)

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CXCR4 pharmacogical inhibition reduces bone and soft tissue metastatic burden by affecting tumor growth and tumorigenic potential in prostate cancer preclinical models.

scientific article published on 12 June 2015

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26073897%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

CXCR4 pharmacogical inhibition reduces bone and soft tissue metastatic burden by affecting tumor growth and tumorigenic potential in prostate cancer preclinical models (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26073897%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Giovanni Luca Gravina

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26073897%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Enrico Ricevuto

6

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Europe PubMed Central

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17 February 2020

Emmanuele A. Jannini

10

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Europe PubMed Central

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17 February 2020

2

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17 February 2020

Assunta Leda Biordi

5

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Europe PubMed Central

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17 February 2020

Ernesto Di Cesare

9

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17 February 2020

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Paola Muzi

3

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Europe PubMed Central

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17 February 2020

Luca Ventura

4

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Europe PubMed Central

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17 February 2020

Simona Pompili

7

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17 February 2020

Claudia Mattei

8

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Europe PubMed Central

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17 February 2020

Claudio Festuccia

11

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17 February 2020

publication date

12 June 2015

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17 February 2020

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17 February 2020

75

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17 February 2020

12

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17 February 2020

1227-1246

1 reference

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17 February 2020

Estimates of cancer incidence and mortality in Europe in 2008.

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

Biology and clinical management of prostate cancer bone metastasis

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

Therapeutic options for hormone-refractory prostate cancer in 2007.

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

Clinical trial update and novel therapeutic approaches for metastatic prostate cancer.

1 reference

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21 January 2018

Occupy tissue: the movement in cancer metastasis

1 reference

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Pathological roles of invadopodia in cancer invasion and metastasis

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21 January 2018

CXCR4 regulates growth of both primary and metastatic breast cancer

1 reference

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21 January 2018

Stromal derived factor-1 (SDF-1/CXCL12) and CXCR4 in renal cell carcinoma metastasis

1 reference

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21 January 2018

CXCL12-CXCR4 axis in angiogenesis, metastasis and stem cell mobilization.

1 reference

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21 January 2018

Regulation of VEGF, MMP-9 and metastasis by CXCR4 in a prostate cancer cell line

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

The role of IL-8 in the SDF-1α/CXCR4-induced angiogenesis of laryngeal and hypopharyngeal squamous cell carcinoma.

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

CXCL12/CXCR4 signaling activates Akt-1 and MMP-9 expression in prostate cancer cells: the role of bone microenvironment-associated CXCL12.

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

CXCR4 chemokine receptor mediates prostate tumor cell adhesion through alpha5 and beta3 integrins

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

Expression and activation of alpha v beta 3 integrins by SDF-1/CXC12 increases the aggressiveness of prostate cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

Thromboxane A₂ receptor signaling facilitates tumor colonization through P-selectin-mediated interaction of tumor cells with platelets and endothelial cells.

1 reference

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21 January 2018

RNAi-mediated silencing of VEGF-C inhibits non-small cell lung cancer progression by simultaneously down-regulating the CXCR4, CCR7, VEGFR-2 and VEGFR-3-dependent axes-induced ERK, p38 and AKT signalling pathways

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100.

1 reference

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21 January 2018

A phase 1/2 study of chemosensitization with the CXCR4 antagonist plerixafor in relapsed or refractory acute myeloid leukemia

1 reference

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21 January 2018

Effective inhibition of metastases and primary tumor growth with CTCE-9908 in esophageal cancer

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

CXCR4/SDF-1 axis is involved in lymph node metastasis of gastric carcinoma

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

Involvement of CXCR4 chemokine receptor in metastastic HER2-positive esophageal cancer

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

Effects of transplantation of adipose tissue-derived stem cells on prostate tumor

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

CXCL12/CXCR4 transactivates HER2 in lipid rafts of prostate cancer cells and promotes growth of metastatic deposits in bone

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

Targeting CXCR4 with CTCE-9908 inhibits prostate tumor metastasis

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

Suppression of EGF-R signaling reduces the incidence of prostate cancer metastasis in nude mice

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

Bone metastatic LNCaP-derivative C4-2B prostate cancer cell line mineralizes in vitro

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase.

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

Xenografts of primary human prostatic carcinoma

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

XPO1/CRM1-selective inhibitors of nuclear export (SINE) reduce tumor spreading and improve overall survival in preclinical models of prostate cancer (PCa).

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

Molecular characterization of human prostate carcinoma cell lines

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

Pyrazolo[3,4-d]pyrimidines c-Src inhibitors reduce epidermal growth factor-induced migration in prostate cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

Bombesin-dependent pro-MMP-9 activation in prostatic cancer cells requires beta1 integrin engagement

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

Bicalutamide increases phospho-Akt levels through Her2 in patients with prostate cancer

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

The TORC1/TORC2 inhibitor, Palomid 529, reduces tumor growth and sensitizes to docetaxel and cisplatin in aggressive and hormone-refractory prostate cancer cells.

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

Synergistic antitumor activity of epidermal growth factor receptor tyrosine kinase inhibitor gefitinib and IFN-alpha in head and neck cancer cells in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

The bisphosphonate olpadronate inhibits skeletal prostate cancer progression in a green fluorescent protein nude mouse model

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

CXCR4 inhibition with AMD3100 sensitizes prostate cancer to docetaxel chemotherapy

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

PAUF functions in the metastasis of human pancreatic cancer cells and upregulates CXCR4 expression

1 reference

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21 January 2018

The chemokine CXCL12 and its receptor CXCR4 promote glioma stem cell-mediated VEGF production and tumour angiogenesis via PI3K/AKT signalling.

1 reference

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21 January 2018

p53 status in stromal fibroblasts modulates tumor growth in an SDF1-dependent manner.

1 reference

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21 January 2018

Skeletal localization and neutralization of the SDF-1(CXCL12)/CXCR4 axis blocks prostate cancer metastasis and growth in osseous sites in vivo.

1 reference

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21 January 2018

A CXCR4 antagonist CTCE-9908 inhibits primary tumor growth and metastasis of breast cancer

1 reference

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21 January 2018

Effects of CXCR4 antagonist CTCE-9908 on prostate tumor growth

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23007

21 January 2018

Residual prostate cancer cells after docetaxel therapy increase the tumorigenic potential via constitutive signaling of CXCR4, ERK1/2 and c-Myc

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21 January 2018

Androgen receptor in human prostate cancer-associated fibroblasts promotes prostate cancer epithelial cell growth and invasion

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21 January 2018

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