(Q52972682)

10 May 2018

title

Signaling states of rhodopsin. Retinal provides a scaffold for activating proton transfer switches. (English)

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10 May 2018

author

Wolfgang Gartner

4

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author name string

C K Meyer

1

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10 May 2018

M Bohme

2

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10 May 2018

A Ockenfels

3

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K P Hofmann

5

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O P Ernst

6

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10 May 2018

language of work or name

English

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publication date

1 June 2000

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10 May 2018

Journal of Biological Chemistry

published in

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10 May 2018

volume

275

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10 May 2018

issue

26

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10 May 2018

page(s)

19713-19718

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10 May 2018

Cyclic GMP cascade of vision

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Deprotonation of the Schiff base of rhodopsin is obligate in the activation of the G protein.

21 January 2018

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Functional equivalence of metarhodopsin II and the Gt-activating form of photolyzed bovine rhodopsin

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21 January 2018

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Two different forms of metarhodopsin II: Schiff base deprotonation precedes proton uptake and signaling state

21 January 2018

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Temperature and pH dependence of the metarhodopsin I-metarhodopsin II equilibrium and the binding of metarhodopsin II to G protein in rod disk membranes.

21 January 2018

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The activation process of the alpha1B-adrenergic receptor: potential role of protonation and hydrophobicity of a highly conserved aspartate

21 January 2018

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21 January 2018

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Mechanism of activation of sensory rhodopsin I: evidence for a steric trigger

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The C9 methyl group of retinal interacts with glycine-121 in rhodopsin.

21 January 2018

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Role of the C9 methyl group in rhodopsin activation: characterization of mutant opsins with the artificial chromophore 11-cis-9-demethylretinal.

21 January 2018

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Removal of the 9-methyl group of retinal inhibits signal transduction in the visual process. A Fourier transform infrared and biochemical investigation

21 January 2018

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Structure and function in rhodopsin: rhodopsin mutants with a neutral amino acid at E134 have a partially activated conformation in the dark state

21 January 2018

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Glutamic acid-113 serves as the retinylidene Schiff base counterion in bovine rhodopsin

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Expression of a synthetic bovine rhodopsin gene in monkey kidney cells

21 January 2018

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The role of the retinylidene Schiff base counterion in rhodopsin in determining wavelength absorbance and Schiff base pKa

21 January 2018

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21 January 2018

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Interactions of the beta-ionone ring with the protein in the visual pigment rhodopsin control the activation mechanism. An FTIR and fluorescence study on artificial vertebrate rhodopsins.

21 January 2018

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Rhodopsin-lumirhodopsin phototransition of bovine rhodopsin investigated by Fourier transform infrared difference spectroscopy

21 January 2018

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Identification of glutamic acid 113 as the Schiff base proton acceptor in the metarhodopsin II photointermediate of rhodopsin

21 January 2018

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Regulation of the rhodopsin-transducin interaction by a highly conserved carboxylic acid group

21 January 2018

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The steric trigger in rhodopsin activation

21 January 2018

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21 January 2018

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21 January 2018

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G-protein-effector coupling: a real-time light-scattering assay for transducin-phosphodiesterase interaction

21 January 2018

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21 January 2018

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Photoregeneration of bovine rhodopsin from its signaling state

21 January 2018

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Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin

21 January 2018

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Conformational changes in rhodopsin. Movement of helix f detected by site-specific chemical labeling and fluorescence spectroscopy

21 January 2018

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An additional methyl group at the 10-position of retinal dramatically slows down the kinetics of the rhodopsin photocascade

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M000603200

1 reference

10 May 2018

1 reference

10 May 2018