(Q52973183)

10 May 2018

title

Gonadotropin-releasing hormone receptor initiates multiple signaling pathways by exclusively coupling to G(q/11) proteins. (English)

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10 May 2018

author

Robert Grosse

1

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10 May 2018

author name string

Schmid A

2

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10 May 2018

Schöneberg T

3

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Herrlich A

4

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10 May 2018

Muhn P

5

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10 May 2018

Schultz G

6

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Gudermann T

7

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language of work or name

English

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publication date

1 March 2000

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10 May 2018

Journal of Biological Chemistry

published in

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10 May 2018

volume

275

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10 May 2018

issue

13

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10 May 2018

page(s)

9193-9200

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10 May 2018

Studies of gonadotropin-releasing hormone (GnRH) action using GnRH receptor-expressing pituitary cell lines

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Inhibitory effects of analogs of luteinizing hormone-releasing hormone on the growth of the androgen-independent Dunning R-3327-AT-1 rat prostate cancer

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The nucleotide sequences of human GnRH receptors in breast and ovarian tumors are identical with that found in pituitary

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Inhibition of growth of OV-1063 human epithelial ovarian cancer xenografts in nude mice by treatment with luteinizing hormone-releasing hormone antagonist SB-75.

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Inhibition of Gonadotropin-Releasing Hormone Receptor Signaling by Expression of a Splice Variant of the Human Receptor

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Activation of MAP kinase by the LHRH receptor through a dual mechanism involving protein kinase C and a pertussis toxin-sensitive G protein

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Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol

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Identification of a receptor/G-protein contact site critical for signaling specificity and G-protein activation

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Gonadotropin-releasing hormone receptor couples to multiple G proteins in rat gonadotrophs and in GGH3 cells: evidence from palmitoylation and overexpression of G proteins

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Stable transfection of GH3 cells with rat gonadotropin-releasing hormone receptor complementary deoxyribonucleic acid results in expression of a receptor coupled to cyclic adenosine 3',5'-monophosphate-dependent prolactin release via a G-protein

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The third intracellular loop of the rat gonadotropin-releasing hormone receptor couples the receptor to Gs- and G(q/11)-mediated signal transduction pathways: evidence from loop fragment transfection in GGH3 cells

21 January 2018

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Cell Lines of the Pituitary Gonadotrope Lineage Derived by Targeted Oncogenesis in Transgenic Mice

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Intracellular Responses to Gonadotropin-Releasing Hormone in a Clonal Cell Line of the Gonadotrope Lineage

21 January 2018

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Estradiol regulates gonadotropin-releasing hormone receptor number, growth and inositol phosphate production in alpha T3-1 cells

21 January 2018

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Regulation of phosphoinositide-specific phospholipase C isozymes

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Gonadotrophin-releasing hormone receptor agonist-mediated down-regulation of Gq alpha/G11 alpha (pertussis toxin-insensitive) G proteins in alpha T3-1 gonadotroph cells reflects increased G protein turnover but not alterations in mRNA levels

21 January 2018

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GnRH and PACAP action in gonadotropes: cross-talk between phosphoinositidase C and adenylyl cyclase mediated signaling pathways

21 January 2018

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Cyclic AMP stimulates luteinizing-hormone (lutropin) exocytosis in permeabilized sheep anterior-pituitary cells. Synergism with protein kinase C and calcium

21 January 2018

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G proteins of the Gq family couple the H2 histamine receptor to phospholipase C.

21 January 2018

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First intracellular loop of the human cholecystokinin-A receptor is essential for cyclic AMP signaling in transfected HEK-293 cells

21 January 2018

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Rat gonadotropin-releasing hormone receptor expressed in insect cells induces activation of adenylyl cyclase

21 January 2018

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Gonadotropin-releasing hormone receptors with intracellular carboxyl-terminal tails undergo acute desensitization of total inositol phosphate production and exhibit accelerated internalization kinetics

21 January 2018

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Differences in structure-function relations between nonmammalian and mammalian gonadotropin-releasing hormone receptors

21 January 2018

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Functional and structural complexity of signal transduction via G-protein-coupled receptors

21 January 2018

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Regulation of Gq/11 by the Gonadotropin-Releasing Hormone Receptor

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.275.13.9193

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10 May 2018

PubMed ID

10734055

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10 May 2018