(Q53125766)

English

Curcumin induces cell death and restores tamoxifen sensitivity in the antiestrogen-resistant breast cancer cell lines MCF-7/LCC2 and MCF-7/LCC9.

scientific article published on 8 January 2013

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21 February 2020

Curcumin induces cell death and restores tamoxifen sensitivity in the antiestrogen-resistant breast cancer cell lines MCF-7/LCC2 and MCF-7/LCC9 (English)

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21 February 2020

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Min Jiang

1

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21 February 2020

Ou Huang

2

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21 February 2020

Xi Zhang

3

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21 February 2020

Zuoquan Xie

4

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21 February 2020

Aijun Shen

5

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21 February 2020

Hongchun Liu

6

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21 February 2020

Meiyu Geng

7

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21 February 2020

Kunwei Shen

8

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21 February 2020

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publication date

8 January 2013

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21 February 2020

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Europe PubMed Central

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21 February 2020

18

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21 February 2020

1

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21 February 2020

701-720

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Europe PubMed Central

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21 February 2020

copyright license

Creative Commons Attribution 4.0 International

8 January 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Mechanisms of tamoxifen resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Curcumin downregulates the inflammatory cytokines CXCL1 and -2 in breast cancer cells via NFkappaB.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the AKT/mTOR and erbB pathways by gefitinib, perifosine and analogs of gonadotropin-releasing hormone I and II to overcome tamoxifen resistance in breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of PI3K/Akt signaling and hormone resistance in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nuclear factor kappa B inhibitor parthenolide restores ICI 182,780 (Faslodex; fulvestrant)-induced apoptosis in antiestrogen-resistant breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic value of Bcl-2 in two independent populations of estrogen receptor positive breast cancer patients treated with adjuvant endocrine therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MCF7/LCC9: an antiestrogen-resistant MCF-7 variant in which acquired resistance to the steroidal antiestrogen ICI 182,780 confers an early cross-resistance to the nonsteroidal antiestrogen tamoxifen

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated Src kinase activity attenuates Tamoxifen response in vitro and is associated with poor prognosis clinically

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The impact of curcumin on breast cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen-stimulated growth of breast cancer due to p21 loss

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The diverse and complex roles of NF-κB subunits in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Downstream targets of growth factor and oestrogen signalling and endocrine resistance: the potential roles of c-Myc, cyclin D1 and cyclin E.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Curcumin improves MMC-based chemotherapy by simultaneously sensitising cancer cells to MMC and reducing MMC-associated side-effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High miR-26a and low CDC2 levels associate with decreased EZH2 expression and with favorable outcome on tamoxifen in metastatic breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual targeting of Src and ER prevents acquired antihormone resistance in breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Curcumin inhibits proliferation of colorectal carcinoma by modulating Akt/mTOR signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combined Src and ER blockade impairs human breast cancer proliferation in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biological determinants of endocrine resistance in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of Akt and mTOR in chemotherapeutic- and hormonal-based drug resistance and response to radiation in breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical trials update: endocrine and biological therapy combinations in the treatment of breast cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Curcumin induces c-jun N-terminal kinase-dependent apoptosis in HCT116 human colon cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Curcumin modulates microRNA-203-mediated regulation of the Src-Akt axis in bladder cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NFκB signaling is important for growth of antiestrogen resistant breast cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the effects of the PI3K/mTOR inhibitors NVP-BEZ235 and GSK2126458 on tamoxifen-resistant breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Curcumin induces down-regulation of EZH2 expression through the MAPK pathway in MDA-MB-435 human breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Curcumin blocks migration and invasion of mouse-rat hybrid retina ganglion cells (N18) through the inhibition of MMP-2, -9, FAK, Rho A and Rock-1 gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen receptor breast cancer phenotypes in the Surveillance, Epidemiology, and End Results database.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Potential Utility of Curcumin in the Treatment of HER-2-Overexpressed Breast Cancer: An In Vitro and In Vivo Comparison Study with Herceptin

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer statistics, 2012

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased expression of EZH2 is associated with upregulation of ER and favorable outcome to tamoxifen in advanced breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Curcumin inhibits carcinogen and nicotine-induced Mammalian target of rapamycin pathway activation in head and neck squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Curcumin down-regulates visfatin expression and inhibits breast cancer cell invasion

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neoadjuvant anastrozole versus tamoxifen in patients receiving goserelin for premenopausal breast cancer (STAGE): a double-blind, randomised phase 3 trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EZH2 promotes a bi-lineage identity in basal-like breast cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MCF7/LCC2: a 4-hydroxytamoxifen resistant human breast cancer variant that retains sensitivity to the steroidal antiestrogen ICI 182,780.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The NFkappaB pathway and endocrine-resistant breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endocrine-responsive breast cancer and strategies for combating resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crosstalk between the estrogen receptor and the HER tyrosine kinase receptor family: molecular mechanism and clinical implications for endocrine therapy resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significance of ER-Src axis in hormonal therapy resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Curcumin inhibits Akt/mammalian target of rapamycin signaling through protein phosphatase-dependent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Curcumin enhances the efficacy of chemotherapy by tailoring p65NFκB-p300 cross-talk in favor of p53-p300 in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor-I activates gene transcription programs strongly associated with poor breast cancer prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress and AP-1 activity in tamoxifen-resistant breast tumors in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/MOLECULES18010701

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23299550%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23299550%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23299550%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

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