(Q53139444)

11 May 2018

title

CD45 regulates GM-CSF, retinoic acid and T-cell homing in intestinal inflammation. (English)

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11 May 2018

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A Samarakoon

1

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11 May 2018

Y A Shim

2

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11 May 2018

M Dosanjh

3

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11 May 2018

M Crickmer

4

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11 May 2018

C Labonté-Raymond

5

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11 May 2018

A A Arif

6

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11 May 2018

P Johnson

7

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11 May 2018

publication date

23 March 2016

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11 May 2018

published in

Mucosal Immunology

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11 May 2018

volume

9

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11 May 2018

issue

6

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11 May 2018

page(s)

1514-1527

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11 May 2018

https://scigraph.springernature.com/pub.10.1038/mi.2016.23

exact match

0 references

cites work

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CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling

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CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation

21 January 2018

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Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice

21 January 2018

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Greatly reduced efficiency of both positive and negative selection of thymocytes in CD45 tyrosine phosphatase-deficient mice

21 January 2018

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Phenotypical and functional alterations in the mucosal immune system of CD45 exon 9 KO mice

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Involvement of lymphocytes in dextran sulfate sodium-induced experimental colitis

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New perspective on dextran sodium sulfate colitis: antigen-specific T cell development during intestinal inflammation

21 January 2018

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Inflammation switches the differentiation program of Ly6Chi monocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon.

21 January 2018

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Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions.

21 January 2018

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Oral tolerance originates in the intestinal immune system and relies on antigen carriage by dendritic cells

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Essential role for CD103 in the T cell-mediated regulation of experimental colitis

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A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

21 January 2018

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Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid

21 January 2018

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Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology.

21 January 2018

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Retinoic acid expression associates with enhanced IL-22 production by γδ T cells and innate lymphoid cells and attenuation of intestinal inflammation.

21 January 2018

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IL-23R+ innate lymphoid cells induce colitis via interleukin-22-dependent mechanism

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CX₃CR1⁺ mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22.

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CD45 down-regulates Lck-mediated CD44 signaling and modulates actin rearrangement in T cells.

21 January 2018

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Retinoic acid is essential for Th1 cell lineage stability and prevents transition to a Th17 cell program

21 January 2018

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Essential role for retinoic acid in the promotion of CD4(+) T cell effector responses via retinoic acid receptor alpha

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Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: Epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity

21 January 2018

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Unique lamina propria stromal cells imprint the functional phenotype of mucosal dendritic cells.

21 January 2018

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Lyn activity protects mice from DSS colitis and regulates the production of IL-22 from innate lymphoid cells.

21 January 2018

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Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease

21 January 2018

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GM-CSF and IL-4 synergistically trigger dendritic cells to acquire retinoic acid-producing capacity

21 January 2018

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Macrophage-restricted interleukin-10 receptor deficiency, but not IL-10 deficiency, causes severe spontaneous colitis

21 January 2018

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21 January 2018

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Regulation of integrin-mediated T cell adhesion by the transmembrane protein tyrosine phosphatase CD45

21 January 2018

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12 December 2020

Innate immune cell CD45 regulates lymphopenia-induced T cell proliferation

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12 December 2020

Characterization of Foxp3+CD4+CD25+ and IL-10-Secreting CD4+CD25+ T Cells during Cure of Colitis

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12 December 2020

CCL25 mediates the localization of recently activated CD8alphabeta(+) lymphocytes to the small-intestinal mucosa

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12 December 2020

Investigating intestinal inflammation in DSS-induced model of IBD.

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12 December 2020

Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses

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12 December 2020

CD45 negatively regulates tumour necrosis factor and interleukin-6 production in dendritic cells

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12 December 2020

Generation of T cells with differential responses to alloantigens in CD45 exon 6-deficient mice

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12 December 2020

Identifiers

DOI

10.1038/MI.2016.23

1 reference

11 May 2018

PubMed ID

27007678

1 reference

11 May 2018