(Q53205825)

English

PHF-tau from Alzheimer's brain comprises four species on SDS-PAGE which can be mimicked by in vitro phosphorylation of human brain tau by glycogen synthase kinase-3 beta.

scientific article published in August 1994

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scholarly article

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Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/8050597

PHF-tau from Alzheimer's brain comprises four species on SDS-PAGE which can be mimicked by in vitro phosphorylation of human brain tau by glycogen synthase kinase-3 beta. (English)

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/8050597

phosphorylation

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based on heuristic

inferred from title

James R. Woodgett

3

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/8050597

Diane P. Hanger

5

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Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/8050597

author name string

Mulot SF

1

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/8050597

Hughes K

2

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/8050597

Anderton BH

4

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Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/8050597

language of work or name

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publication date

1 August 1994

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Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/8050597

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/8050597

349

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Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/8050597

359-364

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Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/8050597

3

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Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/8050597

The carboxyl third of tau is tightly bound to paired helical filaments.

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

A68: a major subunit of paired helical filaments and derivatized forms of normal Tau.

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Abnormal tau species are produced during Alzheimer's disease neurodegenerating process.

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Tau in Alzheimer's disease and Down's syndrome is insoluble and abnormally phosphorylated

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

A68 proteins in Alzheimer's disease are composed of several tau isoforms in a phosphorylated state which affects their electrophoretic mobilities

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Molecular characterization of microtubule-associated proteins tau and MAP2.

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

The Alzheimer-like phosphorylation of tau protein reduces microtubule binding and involves Ser-Pro and Thr-Pro motifs

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding.

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Phosphorylation-dependent epitopes of neurofilament antibodies on tau protein and relationship with Alzheimer tau

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase.

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau.

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Proline-directed kinase systems in Alzheimer's disease pathology.

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Implication of brain cdc2 and MAP2 kinases in the phosphorylation of tau protein in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

A cdc2-related kinase PSSALRE/cdk5 is homologous with the 30 kDa subunit of tau protein kinase II, a proline-directed protein kinase associated with microtubule

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Phosphorylation of tau by proline-directed protein kinase (p34cdc2/p58cyclin A) decreases tau-induced microtubule assembly and antibody SMI33 reactivity.

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Differences in the abilities of human tau isoforms to promote microtubule assembly.

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Neurofilament monoclonal antibodies RT97 and 8D8 recognize different modified epitopes in paired helical filament-tau in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Baculovirus-mediated expression and characterisation of rat glycogen synthase kinase-3 beta, the mammalian homologue of the Drosophila melanogaster zeste-white 3sgg homeotic gene product

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Monoclonal antibodies show that neurofibrillary tangles and neurofilaments share antigenic determinants.

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Epitopes that span the tau molecule are shared with paired helical filaments.

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Monoclonal antibodies with selective specificity for Alzheimer Tau are directed against phosphatase-sensitive epitopes

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

The distribution of tau in the mammalian central nervous system

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Expression and phosphorylation of a three-repeat isoform of tau in transfected non-neuronal cells

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Multisite phosphorylation of glycogen synthase

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Integration of mass spectrometry into strategies for peptide synthesis

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Multisite phosphorylation of glycogen synthase from rabbit skeletal muscle. Phosphorylation of site 5 by glycogen synthase kinase-5 (casein kinase-II) is a prerequisite for phosphorylation of sites 3 by glycogen synthase kinase-3

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2900702-0

21 January 2018

Identifiers

10.1016/0014-5793(94)00702-0

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/8050597

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/8050597

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