(Q53217680)

http://europepmc.org/abstract/MED/26086949

12 May 2018

title

LGR5 Promotes Breast Cancer Progression and Maintains Stem-Like Cells Through Activation of Wnt/β-Catenin Signaling. (English)

1 reference

http://europepmc.org/abstract/MED/26086949

12 May 2018

author

Yanan Kong

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26086949%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

0 references

Lu Yang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26086949%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Hailin Tang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26086949%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Xinhua Xie

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26086949%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Jianping Chen

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26086949%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Cailu Song

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26086949%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Xiaoping Liu

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26086949%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Feng Ye

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26086949%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Ning Li

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26086949%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Neng Wang

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26086949%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Xiaoming Xie

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26086949%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

publication date

14 July 2015

1 reference

http://europepmc.org/abstract/MED/26086949

12 May 2018

published in

Stem Cells

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26086949%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26086949%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26086949%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

2913-2924

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26086949%20AND%20SRC:MED&resulttype=core&format=json

Cancer stem cells in solid tumors

13 June 2020

cites work

1 reference

Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

21 January 2018

1 reference

Stem cells, cancer, and cancer stem cells

21 January 2018

1 reference

Prospective identification of tumorigenic breast cancer cells

21 January 2018

1 reference

Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

21 January 2018

1 reference

Cancer stem cells contribute to cisplatin resistance in Brca1/p53-mediated mouse mammary tumors.

21 January 2018

1 reference

Association of breast cancer stem cells identified by aldehyde dehydrogenase 1 expression with resistance to sequential Paclitaxel and epirubicin-based chemotherapy for breast cancers.

21 January 2018

1 reference

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

21 January 2018

1 reference

R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling

21 January 2018

1 reference

ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner

21 January 2018

1 reference

Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors

21 January 2018

1 reference

Identification of stem cells in small intestine and colon by marker gene Lgr5

21 January 2018

1 reference

Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro

21 January 2018

1 reference

Lgr5 marks cycling, yet long-lived, hair follicle stem cells.

21 January 2018

1 reference

Lgr5(+ve) stem/progenitor cells contribute to nephron formation during kidney development.

21 January 2018

1 reference

Lgr5-expressing cells are sufficient and necessary for postnatal mammary gland organogenesis

21 January 2018

1 reference

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

21 January 2018

1 reference

Crypt stem cells as the cells-of-origin of intestinal cancer

21 January 2018

1 reference

Identification of overexpression of orphan G protein-coupled receptor GPR49 in human colon and ovarian primary tumors

21 January 2018

1 reference

Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs

21 January 2018

1 reference

Overexpression of orphan G-protein-coupled receptor, Gpr49, in human hepatocellular carcinomas with beta-catenin mutations

21 January 2018

1 reference

Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas

21 January 2018

1 reference

In situ identification of bipotent stem cells in the mammary gland.

21 January 2018

1 reference

Epithelial-mesenchymal transitions: insights from development

21 January 2018

1 reference

Biomarkers for epithelial-mesenchymal transitions

21 January 2018

1 reference

Emodin represses TWIST1-induced epithelial-mesenchymal transitions in head and neck squamous cell carcinoma cells by inhibiting the β-catenin and Akt pathways

21 January 2018

1 reference

miR-185 suppresses tumor proliferation by directly targeting E2F6 and DNMT1 and indirectly upregulating BRCA1 in triple-negative breast cancer

21 January 2018

1 reference

miR-200b and miR-200c as prognostic factors and mediators of gastric cancer cell progression.

21 January 2018

1 reference

The epithelial-mesenchymal transition generates cells with properties of stem cells

21 January 2018

1 reference

The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse

21 January 2018

1 reference

A novel splice variant of the stem cell marker LGR5/GPR49 is correlated with the risk of tumor-related death in soft-tissue sarcoma patients

21 January 2018

1 reference

Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal

21 January 2018

1 reference

Lgr5-EGFP marks taste bud stem/progenitor cells in posterior tongue

21 January 2018

1 reference

Lgr5(+) gastric stem cells divide symmetrically to effect epithelial homeostasis in the pylorus

21 January 2018

1 reference

Identification of Lgr5-independent spheroid-generating progenitors of the mouse fetal intestinal epithelium

21 January 2018

1 reference

G-protein-coupled receptor GPR49 is up-regulated in basal cell carcinoma and promotes cell proliferation and tumor formation.

21 January 2018

1 reference

LGR5 is a negative regulator of tumourigenicity, antagonizes Wnt signalling and regulates cell adhesion in colorectal cancer cell lines

21 January 2018

1 reference

Epithelial-mesenchymal transitions in tumour progression

21 January 2018

1 reference

Molecular requirements for epithelial-mesenchymal transition during tumor progression

21 January 2018

1 reference

New insights of epithelial-mesenchymal transition in cancer metastasis

21 January 2018

1 reference

Epithelial and mesenchymal subpopulations within normal basal breast cell lines exhibit distinct stem cell/progenitor properties

21 January 2018

1 reference

Cancer stem cells: current status and evolving complexities

21 January 2018

1 reference

Stem cell signaling. An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control

21 January 2018

1 reference

Generation of a functional mammary gland from a single stem cell

21 January 2018

1 reference

Wnt proteins are self-renewal factors for mammary stem cells and promote their long-term expansion in culture

21 January 2018

1 reference

LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling.

21 January 2018

1 reference

Direct Evidence for Epithelial-Mesenchymal Transitions in Breast Cancer

21 January 2018

1 reference

Distinct stem cells contribute to mammary gland development and maintenance

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/STEM.2083

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26086949%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference