(Q53221094)

12 May 2018

title

Low level of c-kit expression marks deeply quiescent murine hematopoietic stem cells. (English)

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12 May 2018

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Yoshikazu Matsuoka

1

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12 May 2018

Yutaka Sasaki

2

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Ryusuke Nakatsuka

3

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Masaya Takahashi

4

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Ryuji Iwaki

5

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Yasushi Uemura

6

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Yoshiaki Sonoda

7

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publication date

1 November 2011

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12 May 2018

published in

Stem Cells

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volume

29

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issue

11

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page(s)

1783-1791

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In vitro self-renewal division of hematopoietic stem cells

cites work

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Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation

21 January 2018

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Heterozygous kit mutants with little or no apparent anemia exhibit large defects in overall hematopoietic stem cell function

21 January 2018

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Viable c-Kit(W/W) mutants reveal pivotal role for c-kit in the maintenance of lymphopoiesis

21 January 2018

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Kit regulates maintenance of quiescent hematopoietic stem cells.

21 January 2018

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Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells

21 January 2018

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Membrane-bound stem cell factor is a key regulator in the initial lodgment of stem cells within the endosteal marrow region.

21 January 2018

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Efficient transplantation via antibody-based clearance of hematopoietic stem cell niches

21 January 2018

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Expression and function of c-kit in hemopoietic progenitor cells

21 January 2018

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In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells

21 January 2018

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Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells

21 January 2018

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Lipid rafts are required for Kit survival and proliferation signals

21 January 2018

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Enforced expression of cyclin D2 enhances the proliferative potential of myeloid progenitors, accelerates in vivo myeloid reconstitution, and promotes rescue of mice from lethal myeloablation

21 January 2018

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Marginal expression of CXCR4 on c-kit(+)Sca-1 (+)Lineage (-) hematopoietic stem/progenitor cells.

21 January 2018

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Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia

21 January 2018

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Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches.

21 January 2018

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SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity

21 January 2018

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AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species.

21 January 2018

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Dormant and self-renewing hematopoietic stem cells and their niches

21 January 2018

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Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche

21 January 2018

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Repopulating activity of ex vivo-expanded murine hematopoietic stem cells resides in the CD48-c-Kit+Sca-1+lineage marker- cell population.

21 January 2018

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The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus

21 January 2018

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The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene

21 January 2018

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Functional characterization of a novel hematopoietic stem cell and its place in the c-Kit maturation pathway in bone marrow cell development

21 January 2018

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Wnt3a activates dormant c-Kit(-) bone marrow-derived cells with short-term multilineage hematopoietic reconstitution capacity.

21 January 2018

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TGF-beta as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation.

21 January 2018

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Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair

21 January 2018

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Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist

21 January 2018

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Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/STEM.721

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12 May 2018

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12 May 2018