(Q53250657)

12 May 2018

title

Urokinase-type plasminogen activator inhibits amyloid-beta neurotoxicity and fibrillogenesis via plasminogen. (English)

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12 May 2018

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H Michael Tucker

1

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Muthoni Kihiko-Ehmann

series ordinal

2

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Steven Estus

series ordinal

3

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publication date

1 October 2002

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Journal of Neuroscience Research

published in

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volume

70

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issue

2

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page(s)

249-255

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12 May 2018

Microglia express the type 2 plasminogen activator inhibitor in the brain of control subjects and patients with Alzheimer's disease

cites work

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The plasminogen activation system in tumor growth, invasion, and metastasis

21 January 2018

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Tissue plasminogen activator contributes to the late phase of LTP and to synaptic growth in the hippocampal mossy fiber pathway.

21 January 2018

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Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures

21 January 2018

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Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination

21 January 2018

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Loss of fibrinogen rescues mice from the pleiotropic effects of plasminogen deficiency.

21 January 2018

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Neuronal death in the hippocampus is promoted by plasmin-catalyzed degradation of laminin.

21 January 2018

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Plasmin cleaves Abeta42 in vitro and prevents its aggregation into beta-pleated sheet structures.

21 January 2018

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The plasminogen-plasmin system

21 January 2018

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Rapid differential endogenous plasminogen activator expression after acute middle cerebral artery occlusion

21 January 2018

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Metabolic regulation of brain Abeta by neprilysin.

21 January 2018

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Nonproteolytic neuroprotection by human recombinant tissue plasminogen activator

21 January 2018

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Apoptosis is induced by beta-amyloid in cultured central nervous system neurons

21 January 2018

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Enhanced hippocampal long-term potentiation and learning by increased neuronal expression of tissue-type plasminogen activator in transgenic mice

21 January 2018

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Susceptibility locus for Alzheimer's disease on chromosome 10.

21 January 2018

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In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity

21 January 2018

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Degradation of amyloid beta-protein by a metalloprotease secreted by microglia and other neural and non-neural cells

21 January 2018

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Neuronal migration is retarded in mice lacking the tissue plasminogen activator gene

21 January 2018

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Alzheimer's disease: genes, proteins, and therapy

21 January 2018

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Neuronal cell death and tPA.

21 January 2018

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Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice

21 January 2018

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Physiological consequences of loss of plasminogen activator gene function in mice

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JNR.10417

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12 May 2018

PubMed ID

12271474

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12 May 2018