(Q53270407)

12 May 2018

title

The human Lgl polarity gene, Hugl-2, induces MET and suppresses Snail tumorigenesis. (English)

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12 May 2018

author

Anja Bosserhoff

4

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12 May 2018

author name string

A Kashyap

1

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12 May 2018

T Zimmerman

2

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12 May 2018

N Ergül

3

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12 May 2018

U Hartman

5

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12 May 2018

V Alla

6

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12 May 2018

F Bataille

7

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12 May 2018

P R Galle

8

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12 May 2018

S Strand

9

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12 May 2018

D Strand

10

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12 May 2018

language of work or name

English

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publication date

14 May 2012

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12 May 2018

published in

Oncogene

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12 May 2018

volume

32

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12 May 2018

issue

11

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12 May 2018

page(s)

1396-1407

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12 May 2018

https://scigraph.springernature.com/pub.10.1038/onc.2012.162

exact match

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cites work

Dlg, Scrib and Lgl regulate neuroblast cell size and mitotic spindle asymmetry

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Drosophila lethal giant larvae neoplastic mutant as a genetic tool for cancer modeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Cell polarity and cancer--cell and tissue polarity as a non-canonical tumor suppressor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

The human protein Hugl-1 substitutes for Drosophila lethal giant larvae tumour suppressor function in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Expression of Dickkopf genes is strongly reduced in malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

aPKCzeta cortical loading is associated with Lgl cytoplasmic release and tumor growth in Drosophila and human epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Reduced expression of Hugl-1, the human homologue of Drosophila tumour suppressor gene lgl, contributes to progression of colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Cell polarity protein Lgl2 is lost or aberrantly localized in gastric dysplasia and adenocarcinoma: an immunohistochemical study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Aberrant splicing of Hugl-1 is associated with hepatocellular carcinoma progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

MicroRNA expression and identification of putative miRNA targets in ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Cross-species comparison of human and mouse intestinal polyps reveals conserved mechanisms in adenomatous polyposis coli (APC)-driven tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Genome-wide analysis of pancreatic cancer using microarray-based techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Gene-expression of metastasized versus non-metastasized primary head and neck squamous cell carcinomas: a pathway-based analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Gene expression predictors of breast cancer outcomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Prediction of high risk Ewing's sarcoma by gene expression profiling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Gene expression analysis by cDNA microarray in oral squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Genetic programs of epithelial cell plasticity directed by transforming growth factor-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Epithelial-mesenchymal transition and the invasive potential of tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Epithelial-mesenchymal transitions in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

SNAI1 expression in colon cancer related with CDH1 and VDR downregulation in normal adjacent tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

The snail superfamily of zinc-finger transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Transcriptional regulation of cell polarity in EMT and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Correlation of Snail expression with histological grade and lymph node status in breast carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

The transcriptional repressor Snail promotes mammary tumor recurrence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Lysyl oxidase-like 2 (LOXL2), a new regulator of cell polarity required for metastatic dissemination of basal-like breast carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Awakening guardian angels: drugging the p53 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Identification of proapoptotic Bim as a tumor suppressor in neoplastic mast cells: role of KIT D816V and effects of various targeted drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Expression of Hugl-1 is strongly reduced in malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Loss of Hugl-1 expression associates with lymph node metastasis in endometrial cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Immunohistochemistry for cell polarity protein lethal giant larvae 2 differentiates pancreatic intraepithelial neoplasia-3 and ductal adenocarcinoma of the pancreas from lower-grade pancreatic intraepithelial neoplasias

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Array CGH identifies distinct DNA copy number profiles of oncogenes and tumor suppressor genes in chromosomal- and microsatellite-unstable sporadic colorectal carcinomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Cutting edge: molecular portrait of human autoimmune disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

An expression profile for diagnosis of lymph node metastases from primary head and neck squamous cell carcinomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

DNA Copy Number Gains at Loci of Growth Factors and Their Receptors in Salivary Gland Adenoid Cystic Carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Snail accelerates cancer invasion by upregulating MMP expression and is associated with poor prognosis of hepatocellular carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

Extinction of E-cadherin expression in breast cancer via a dominant repression pathway acting on proximal promoter elements

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.162

31 March 2020

Identifiers

DOI

10.1038/ONC.2012.162

1 reference

12 May 2018

1 reference

12 May 2018