(Q53280723)

12 May 2018

title

TRIM proteins and cancer. (English)

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12 May 2018

author

Shigetsugu Hatakeyama

series ordinal

1

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12 May 2018

language of work or name

English

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publication date

7 October 2011

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12 May 2018

published in

Nature Reviews Cancer

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12 May 2018

volume

11

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12 May 2018

page(s)

792-804

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12 May 2018

issue

11

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12 May 2018

https://scigraph.springernature.com/pub.10.1038/nrc3139

exact match

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PML regulates p53 stability by sequestering Mdm2 to the nucleolus

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A manually curated network of the PML nuclear body interactome reveals an important role for PML-NBs in SUMOylation dynamics

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A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex

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TRIM68 regulates ligand-dependent transcription of androgen receptor in prostate cancer cells

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Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family

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31 March 2020

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Differentiation-specific association of HP1alpha and HP1beta with chromocentres is correlated with clustering of TIF1beta at these sites

31 March 2020

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KAP1 is associated with peritoneal carcinomatosis in gastric cancer.

31 March 2020

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Doxorubicin down-regulates Kruppel-associated box domain-associated protein 1 sumoylation that relieves its transcription repression on p21WAF1/CIP1 in breast cancer MCF-7 cells

31 March 2020

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Sumoylation of the transcriptional intermediary factor 1beta (TIF1beta), the Co-repressor of the KRAB Multifinger proteins, is required for its transcriptional activity and is modulated by the KRAB domain

31 March 2020

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PHD domain-mediated E3 ligase activity directs intramolecular sumoylation of an adjacent bromodomain required for gene silencing

31 March 2020

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Structural insights into human KAP1 PHD finger-bromodomain and its role in gene silencing

31 March 2020

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Recruitment of TIF1γ to chromatin via its PHD finger-bromodomain activates its ubiquitin ligase and transcriptional repressor activities

31 March 2020

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31 March 2020

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31 March 2020

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Cells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycle

31 March 2020

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RET finger protein expression in invasive breast carcinoma: relationship between RFP and ErbB2 expression

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Limb-girdle muscular dystrophy type 2H associated with mutation in TRIM32, a putative E3-ubiquitin-ligase gene

31 March 2020

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Homozygosity mapping with SNP arrays identifies TRIM32, an E3 ubiquitin ligase, as a Bardet-Biedl syndrome gene (BBS11)

31 March 2020

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Deficiency of the E3 ubiquitin ligase TRIM32 in mice leads to a myopathy with a neurogenic component

31 March 2020

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The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors

31 March 2020

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Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage

31 March 2020

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TRIM32 protein sensitizes cells to tumor necrosis factor (TNFα)-induced apoptosis via its RING domain-dependent E3 ligase activity against X-linked inhibitor of apoptosis (XIAP).

31 March 2020

1 reference

RING protein Trim32 associated with skin carcinogenesis has anti-apoptotic and E3-ubiquitin ligase properties

31 March 2020

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Tripartite motif protein 32 facilitates cell growth and migration via degradation of Abl-interactor 2

31 March 2020

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31 March 2020

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Estrogen-responsive RING finger protein controls breast cancer growth

31 March 2020

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Estrogen-responsive finger protein as a new potential biomarker for breast cancer

31 March 2020

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Expression of estrogen-responsive finger protein (Efp) is associated with advanced disease in human epithelial ovarian cancer

31 March 2020

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Efp targets 14-3-3 sigma for proteolysis and promotes breast tumour growth

31 March 2020

1 reference

Underdeveloped uterus and reduced estrogen responsiveness in mice with disruption of the estrogen-responsive finger protein gene, which is a direct target of estrogen receptor alpha.

31 March 2020

1 reference

Ligand-dependent transcription of estrogen receptor alpha is mediated by the ubiquitin ligase EFP.

31 March 2020

1 reference

Regulation of the p53 pathway by ubiquitin and related proteins

31 March 2020

1 reference

Trim24 targets endogenous p53 for degradation

31 March 2020

1 reference

MDM2 interaction with nuclear corepressor KAP1 contributes to p53 inactivation

31 March 2020

1 reference

MAGE-A, mMage-b, and MAGE-C proteins form complexes with KAP1 and suppress p53-dependent apoptosis in MAGE-positive cell lines

31 March 2020

1 reference

Ret finger protein 2 enhances ionizing radiation-induced apoptosis via degradation of AKT and MDM2

31 March 2020

1 reference

Cloning and gene mapping of the chromosome 13q14 region deleted in chronic lymphocytic leukemia

31 March 2020

1 reference

Nucleotide sequence, transcription map, and mutation analysis of the 13q14 chromosomal region deleted in B-cell chronic lymphocytic leukemia

31 March 2020

1 reference

DLEU2 encodes an antisense RNA for the putative bicistronic RFP2/LEU5 gene in humans and mouse

31 March 2020

1 reference

The product of the ataxia-telangiectasia group D complementing gene, ATDC, interacts with a protein kinase C substrate and inhibitor

31 March 2020

1 reference

Stable radioresistance in ataxia-telangiectasia cells containing DNA from normal human cells

31 March 2020

1 reference

A radiation hybrid map of human chromosome 11q22-q23 containing the ataxia-telangiectasia disease locus

31 March 2020

1 reference

The ATDC (TRIM29) protein binds p53 and antagonizes p53-mediated functions

31 March 2020

1 reference

Histone deacetylase 9 (HDAC9) regulates the functions of the ATDC (TRIM29) protein.

31 March 2020

1 reference

TRIM29 negatively regulates p53 via inhibition of Tip60.

31 March 2020

1 reference

Characterization of cell-type specific profiles in tissues and isolated cells from squamous cell carcinomas of the lung

31 March 2020

1 reference

Gene expression in the urinary bladder: a common carcinoma in situ gene expression signature exists disregarding histopathological classification.

31 March 2020

1 reference

Gene expression patterns distinguish colonoscopically isolated human aberrant crypt foci from normal colonic mucosa

31 March 2020

1 reference

Gene expression profiles in primary ovarian serous papillary tumors and normal ovarian epithelium: identification of candidate molecular markers for ovarian cancer diagnosis and therapy

31 March 2020

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Global expression changes of constitutive and hormonally regulated genes during endometrial neoplastic transformation

31 March 2020

1 reference

Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells

31 March 2020

1 reference

Oncogenic function of ATDC in pancreatic cancer through Wnt pathway activation and beta-catenin stabilization

31 March 2020

1 reference

Tripartite motif-containing 29 (TRIM29) is a novel marker for lymph node metastasis in gastric cancer

31 March 2020

1 reference

The interferon-inducible Staf50 gene is downregulated during T cell costimulation by CD2 and CD28.

31 March 2020

1 reference

Staf50 is a novel p53 target gene conferring reduced clonogenic growth of leukemic U-937 cells.

31 March 2020

1 reference

Retinoid-induced growth arrest of breast carcinoma cells involves co-activation of multiple growth-inhibitory genes

31 March 2020

1 reference

Characterization of TRIM31, upregulated in gastric adenocarcinoma, as a novel RBCC protein

31 March 2020

1 reference

The cellular level of TRIM31, an RBCC protein overexpressed in gastric cancer, is regulated by multiple mechanisms including the ubiquitin-proteasome system

31 March 2020

1 reference

TRIM31 interacts with p52(Shc) and inhibits Src-induced anchorage-independent growth.

31 March 2020

1 reference

TRIM40 promotes neddylation of IKKγ and is downregulated in gastrointestinal cancers

31 March 2020

1 reference

Cancer and inflammation: a complex relationship.

31 March 2020

1 reference

A novel RING finger-B box-coiled-coil protein, GERP

31 March 2020

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TRIM8/GERP RING finger protein interacts with SOCS-1

31 March 2020

1 reference

TRIM8 modulates STAT3 activity through negative regulation of PIAS3.

31 March 2020

1 reference

TRIM8 regulates Nanog via Hsp90β-mediated nuclear translocation of STAT3 in embryonic stem cells

31 March 2020

1 reference

Molecular classification of nodal metastasis in primary larynx squamous cell carcinoma

31 March 2020

1 reference

Frequency, characteristics, and reversibility of peripheral neuropathy during treatment of advanced multiple myeloma with bortezomib

31 March 2020

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Evaluation of the proteasome inhibitor MLN9708 in preclinical models of human cancer

31 March 2020

1 reference

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

31 March 2020

1 reference

Inhibiting Hdm2 and ubiquitin-activating enzyme: targeting the ubiquitin conjugating system in cancer

31 March 2020

1 reference

Discovery of new pyridoacridine alkaloids from Lissoclinum cf. badium that inhibit the ubiquitin ligase activity of Hdm2 and stabilize p53.

31 March 2020

1 reference

Identification of inhibitors for MDM2 ubiquitin ligase activity from natural product extracts by a novel high-throughput electrochemiluminescent screen

31 March 2020

1 reference

A cosmid and cDNA fine physical map of a human chromosome 13q14 region frequently lost in B-cell chronic lymphocytic leukemia and identification of a new putative tumor suppressor gene, Leu5

31 March 2020

1 reference

Distinct organization of the candidate tumor suppressor gene RFP2 in human and mouse: multiple mRNA isoforms in both species- and human-specific antisense transcript RFP2OS.

31 March 2020

1 reference

High-resolution oligonucleotide array-CGH pinpoints genes involved in cryptic losses in chronic lymphocytic leukemia

31 March 2020

1 reference

Development of a highly efficient expression cDNA cloning system: application to oncogene isolation

31 March 2020

1 reference

Increasing 14-3-3 sigma expression with declining estrogen receptor alpha and estrogen-responsive finger protein expression defines malignant progression of endometrial carcinoma

31 March 2020

1 reference

Transcription intermediary factor 1γ is a tumor suppressor in mouse and human chronic myelomonocytic leukemia

31 March 2020

1 reference

Molecular pathogenesis of B-cell chronic lymphocytic leukemia: analysis of 13q14 chromosomal deletions.

31 March 2020

1 reference

12 December 2020

Cell differentiation induces TIF1beta association with centromeric heterochromatin via an HP1 interaction.

1 reference

12 December 2020

PML is induced by oncogenic ras and promotes premature senescence

1 reference

12 December 2020

The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells.

1 reference

12 December 2020

Expression of Efp, VEGF and bFGF in normal, hyperplastic and malignant endometrial tissue

1 reference

12 December 2020

A novel nuclear substructure, ND10: distribution in normal and neoplastic human tissues

1 reference

12 December 2020

Frequent rearrangements of chromosomes 1, 7, and 8 in primary liver cancer

1 reference

12 December 2020

PIC 1, a novel ubiquitin-like protein which interacts with the PML component of a multiprotein complex that is disrupted in acute promyelocytic leukaemia

1 reference

12 December 2020

TRIM32 promotes neural differentiation through retinoic acid receptor-mediated transcription.

1 reference

12 December 2020

Cloning of a candidate gene for ataxia-telangiectasia group D

1 reference

12 December 2020

The putative nuclear receptor mediator TIF1alpha is tightly associated with euchromatin

1 reference

12 December 2020

SUMO-1 modification of the acute promyelocytic leukaemia protein PML: implications for nuclear localisation

1 reference

12 December 2020

The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18

1 reference

12 December 2020

Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1

1 reference

12 December 2020

Isolation and characterization of cDNA encoding a human nuclear antigen predominantly recognized by autoantibodies from patients with primary biliary cirrhosis

1 reference

12 December 2020

The PHD finger: implications for chromatin-mediated transcriptional regulation

1 reference

12 December 2020

A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors

1 reference

12 December 2020

Ret finger protein is a normal component of PML nuclear bodies and interacts directly with PML

1 reference

12 December 2020

Transcriptional induction of the PML growth suppressor gene by interferons is mediated through an ISRE and a GAS element.

1 reference

12 December 2020

PML NBs associate with the hMre11 complex and p53 at sites of irradiation induced DNA damage

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRC3139

1 reference

12 May 2018

Dimensions Publication ID

0 references

1 reference

12 May 2018