(Q53281601)

13 May 2018

title

Alzheimer disease: presenilin springs a leak. (English)

1 reference

13 May 2018

author name string

Sam Gandy

series ordinal

1

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13 May 2018

Mark K Doeven

series ordinal

2

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13 May 2018

Bert Poolman

series ordinal

3

1 reference

13 May 2018

language of work or name

English

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publication date

1 October 2006

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13 May 2018

published in

Nature Medicine

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13 May 2018

volume

12

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13 May 2018

issue

10

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13 May 2018

page(s)

1121-1123

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13 May 2018

https://scigraph.springernature.com/pub.10.1038/nm1006-1121

exact match

0 references

cites work

Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1121

Altered oxidation and signal transduction systems in fibroblasts from Alzheimer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1121

Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1121

A protein-conducting channel in the endoplasmic reticulum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1121

Presenilin-1 mutation L271V results in altered exon 8 splicing and Alzheimer's disease with non-cored plaques and no neuritic dystrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1121

Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1121

Hypothesis on the regulation of cytosol calcium concentration and the aging brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1121

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1121

Effect of gamma-secretase inhibitors on muscarinic receptor-mediated calcium signaling in human salivary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1121

Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1121

A novel presenilin 1 mutation associated with Pick's disease but not beta-amyloid plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1121

Common structure and toxic function of amyloid oligomers implies a common mechanism of pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1121

Volume-activated chloride currents are not correlated with P-glycoprotein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM1006-1121

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NM1006-1121

1 reference

13 May 2018

1 reference

13 May 2018