(Q53288339)

13 May 2018

title

RUNX3 in oncogenic and anti-oncogenic signaling in gastrointestinal cancers. (English)

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13 May 2018

author name string

Kosei Ito

series ordinal

1

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13 May 2018

publication date

1 May 2011

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13 May 2018

Journal of Cellular Biochemistry

published in

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13 May 2018

volume

112

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13 May 2018

issue

5

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13 May 2018

page(s)

1243-1249

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13 May 2018

Identification of stem cells in small intestine and colon by marker gene Lgr5

cites work

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Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro

21 January 2018

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Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB

21 January 2018

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The RUNX genes: gain or loss of function in cancer

21 January 2018

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Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia

21 January 2018

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Claudin-1 has tumor suppressive activity and is a direct target of RUNX3 in gastric epithelial cells.

21 January 2018

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RUNX3 suppresses gastric epithelial cell growth by inducing p21(WAF1/Cip1) expression in cooperation with transforming growth factor {beta}-activated SMAD.

21 January 2018

1 reference

RUNX3 is multifunctional in carcinogenesis of multiple solid tumors

21 January 2018

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KLF4 interacts with beta-catenin/TCF4 and blocks p300/CBP recruitment by beta-catenin

21 January 2018

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Runx3-/- gastric epithelial cells differentiate into intestinal type cells

21 January 2018

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Claudins in occluding junctions of humans and flies

21 January 2018

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The CpG island methylator phenotype and chromosomal instability are inversely correlated in sporadic colorectal cancer.

21 January 2018

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Src kinase phosphorylates RUNX3 at tyrosine residues and localizes the protein in the cytoplasm

21 January 2018

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Inhibition of growth of mouse gastric cancer cells by Runx3, a novel tumor suppressor

21 January 2018

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Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter

21 January 2018

1 reference

De novo crypt formation and juvenile polyposis on BMP inhibition in mouse intestine.

21 January 2018

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BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling

21 January 2018

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Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis.

21 January 2018

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RUNX transcription factors as key targets of TGF-beta superfamily signaling

21 January 2018

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RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis

21 January 2018

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Runx3 expression in gastrointestinal tract epithelium: resolving the controversy.

21 January 2018

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Loss of Runx3 is a key event in inducing precancerous state of the stomach

21 January 2018

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Gastric cancer development in mice lacking the SHP2 binding site on the IL-6 family co-receptor gp130.

21 January 2018

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RUNX3 inactivation by point mutations and aberrant DNA methylation in bladder tumors.

21 January 2018

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Role of RUNX3 in bone morphogenetic protein signaling in colorectal cancer

21 January 2018

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Causal relationship between the loss of RUNX3 expression and gastric cancer

21 January 2018

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High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk.

21 January 2018

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Potentiation of oxyntic atrophy-induced gastric metaplasia in amphiregulin-deficient mice.

21 January 2018

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Hyperplastic gastric tumors with spasmolytic polypeptide-expressing metaplasia caused by tumor necrosis factor-alpha-dependent inflammation in cyclooxygenase-2/microsomal prostaglandin E synthase-1 transgenic mice.

21 January 2018

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Carcinogenesis in mouse stomach by simultaneous activation of the Wnt signaling and prostaglandin E2 pathway.

21 January 2018

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Helicobacter pylori and gastrointestinal tract adenocarcinomas

21 January 2018

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TFF2 mRNA transcript expression marks a gland progenitor cell of the gastric oxyntic mucosa.

21 January 2018

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Molecular pathology of RUNX3 in human carcinogenesis

21 January 2018

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Stem cells and gastric cancer: role of gastric and intestinal mixed intestinal metaplasia.

21 January 2018

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Development of gastric tumors in Apc(Min/+) mice by the activation of the beta-catenin/Tcf signaling pathway.

21 January 2018

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CpG island methylator phenotype in colorectal cancer

21 January 2018

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Helicobacter pylori CagA targets gastric tumor suppressor RUNX3 for proteasome-mediated degradation

21 January 2018

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Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice.

21 January 2018

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The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

21 January 2018

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Current understanding of SPEM and its standing in the preneoplastic process

21 January 2018

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CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer

21 January 2018

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The RUNX3 tumor suppressor upregulates Bim in gastric epithelial cells undergoing transforming growth factor beta-induced apoptosis

21 January 2018

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Control of gut differentiation and intestinal-type gastric carcinogenesis

21 January 2018

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Genetic variants in RUNX3 and risk of bladder cancer: a haplotype-based analysis.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCB.23047

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13 May 2018

PubMed ID

21465522

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13 May 2018