(Q53288525)

13 May 2018

title

Reduction of phosphorylated tau during memantine treatment of Alzheimer's disease. (English)

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13 May 2018

main subject

phosphorylation

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author name string

Degerman Gunnarsson M

1

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13 May 2018

Kilander L

2

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13 May 2018

Basun H

3

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Lannfelt L

4

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13 May 2018

publication date

14 August 2007

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13 May 2018

Dementia and Geriatric Cognitive Disorders

published in

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13 May 2018

volume

24

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issue

4

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13 May 2018

page(s)

247-252

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13 May 2018

Role of tau protein in both physiological and pathological conditions.

cites work

1 reference

Tau phosphorylation in neuronal cell function and dysfunction

21 January 2018

1 reference

Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

21 January 2018

1 reference

Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease.

21 January 2018

1 reference

CSF markers for incipient Alzheimer's disease

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1 reference

CSF phosphorylated tau--does it constitute an accurate biological test for Alzheimer's disease?

21 January 2018

1 reference

Cerebrospinal fluid levels of biomarkers and activity of acetylcholinesterase (AChE) and butyrylcholinesterase in AD patients before and after treatment with different AChE inhibitors.

21 January 2018

1 reference

Memantine in severe dementia: results of the 9M-Best Study (Benefit and efficacy in severely demented patients during treatment with memantine).

21 January 2018

1 reference

Memantine in moderate-to-severe Alzheimer's disease

21 January 2018

1 reference

Memantine inhibits and reverses the Alzheimer type abnormal hyperphosphorylation of tau and associated neurodegeneration

21 January 2018

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Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

21 January 2018

1 reference

21 January 2018

1 reference

Quantification of tau phosphorylated at threonine 181 in human cerebrospinal fluid: a sandwich ELISA with a synthetic phosphopeptide for standardization.

21 January 2018

1 reference

Cerebrospinal fluid beta-amyloid(1-42) in Alzheimer disease: differences between early- and late-onset Alzheimer disease and stability during the course of disease.

21 January 2018

1 reference

Longitudinal stability of CSF tau levels in Alzheimer patients.

21 January 2018

1 reference

Three-year follow-up of cerebrospinal fluid tau, beta-amyloid 42 and 40 concentrations in Alzheimer's disease.

21 January 2018

1 reference

Apolipoprotein E4 accelerates dementia and increases cerebrospinal fluid tau levels in Alzheimer's disease.

21 January 2018

1 reference

Cerebrospinal fluid biomarkers for disease stage and intensity in cognitively impaired patients.

21 January 2018

1 reference

Follow-up investigations in cerebrospinal fluid of patients with dementia with Lewy bodies and Alzheimer's disease

21 January 2018

1 reference

Failures and successes of NMDA receptor antagonists: molecular basis for the use of open-channel blockers like memantine in the treatment of acute and chronic neurologic insults

21 January 2018

1 reference

Memantine is a clinically well tolerated N-methyl-D-aspartate (NMDA) receptor antagonist--a review of preclinical data

21 January 2018

1 reference

Involvement of I2PP2A in the abnormal hyperphosphorylation of tau and its reversal by Memantine.

21 January 2018

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Up-regulation of inhibitors of protein phosphatase-2A in Alzheimer's disease

21 January 2018

1 reference

Post-translational modifications of tau protein in Alzheimer's disease

21 January 2018

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Phosphoprotein phosphatase activities in Alzheimer disease brain

21 January 2018

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Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation

21 January 2018

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Polymerization of hyperphosphorylated tau into filaments eliminates its inhibitory activity

21 January 2018

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21 January 2018

Identifiers

DOI

10.1159/000107099

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13 May 2018

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13 May 2018