(Q53319436)

13 May 2018

http://europepmc.org/abstract/MED/21613497

title

Stress acts cumulatively to precipitate Alzheimer's disease-like tau pathology and cognitive deficits. (English)

1 reference

13 May 2018

http://europepmc.org/abstract/MED/21613497

0 references

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633145&resulttype=core&format=json

15 May 2020

Ioannis Sotiropoulos

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633145&resulttype=core&format=json

15 May 2020

author name string

Caterina Catania

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633145&resulttype=core&format=json

15 May 2020

Lucilia G Pinto

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633145&resulttype=core&format=json

15 May 2020

Rui Silva

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633145&resulttype=core&format=json

15 May 2020

G Elizabeth Pollerberg

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633145&resulttype=core&format=json

15 May 2020

Akihiko Takashima

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633145&resulttype=core&format=json

15 May 2020

Osborne F X Almeida

8

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633145&resulttype=core&format=json

15 May 2020

language of work or name

English

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publication date

1 May 2011

1 reference

13 May 2018

http://europepmc.org/abstract/MED/21613497

published in

Journal of Neuroscience

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15 May 2020

volume

31

1 reference

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15 May 2020

issue

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633145&resulttype=core&format=json

15 May 2020

page(s)

7840-7847

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633145&resulttype=core&format=json

Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments

15 May 2020

cites work

1 reference

12 December 2020

Reorganization of the morphology of hippocampal neurites and synapses after stress-induced damage correlates with behavioral improvement.

1 reference

12 December 2020

Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments

1 reference

12 December 2020

Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease.

1 reference

12 December 2020

Tau is essential to beta -amyloid-induced neurotoxicity

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12 December 2020

Progressive reduction of synaptophysin message in single neurons in Alzheimer disease

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12 December 2020

Neurofibrillary tangles, amyloid, and memory in aging and mild cognitive impairment

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12 December 2020

Comparative distribution of tau phosphorylated at Ser262 in pre-tangles and tangles

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12 December 2020

Proneness to psychological distress is associated with risk of Alzheimer's disease

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12 December 2020

A case for a non-transgenic animal model of Alzheimer's disease

1 reference

12 December 2020

Correlation of cerebrospinal fluid levels of tau protein phosphorylated at threonine 231 with rates of hippocampal atrophy in Alzheimer disease

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12 December 2020

Cognitive dysfunction, hippocampal atrophy and glucocorticoid feedback in Alzheimer's disease

1 reference

12 December 2020

Increased levels of granular tau oligomers: an early sign of brain aging and Alzheimer's disease

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12 December 2020

Role of Genes and Environments for Explaining Alzheimer Disease

1 reference

12 December 2020

Chronic stress accelerates learning and memory impairments and increases amyloid deposition in APPV717I-CT100 transgenic mice, an Alzheimer's disease model

1 reference

12 December 2020

Depression and risk for Alzheimer disease: systematic review, meta-analysis, and metaregression analysis

1 reference

12 December 2020

Polymerization of hyperphosphorylated tau into filaments eliminates its inhibitory activity

1 reference

12 December 2020

Prior exposure to chronic stress results in enhanced synthesis and release of hippocampal norepinephrine in response to a novel stressor

1 reference

12 December 2020

Glucocorticoids increase amyloid-beta and tau pathology in a mouse model of Alzheimer's disease.

1 reference

12 December 2020

Plasma cortisol and progression of dementia in subjects with Alzheimer-type dementia

1 reference

12 December 2020

Chronic treatment with high doses of corticosterone decreases cytoskeletal proteins in the rat hippocampus

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12 December 2020

Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration

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12 December 2020

The prefrontal cortex as a key target of the maladaptive response to stress

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12 December 2020

Accumulation of pathological tau species and memory loss in a conditional model of tauopathy.

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12 December 2020

A new glucocorticoid hypothesis of brain aging: implications for Alzheimer's disease

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12 December 2020

Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

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12 December 2020

Untangling tau hyperphosphorylation in drug design for neurodegenerative diseases.

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12 December 2020

Acute stress increases interstitial fluid amyloid-beta via corticotropin-releasing factor and neuronal activity

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12 December 2020

Chronic distress and incidence of mild cognitive impairment.

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12 December 2020

Corticotropin-releasing factor receptors differentially regulate stress-induced tau phosphorylation.

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12 December 2020

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

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12 December 2020

The amyloidogenic potential and behavioral correlates of stress.

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12 December 2020

Hyperphosphorylated tau in parahippocampal cortex impairs place learning in aged mice expressing wild-type human tau

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12 December 2020

Multicenter assessment of CSF-phosphorylated tau for the prediction of conversion of MCI.

1 reference

12 December 2020

Effects of altered corticosteroid milieu on rat hippocampal neurochemistry and structure--an in vivo magnetic resonance spectroscopy and imaging study

1 reference

12 December 2020

Amyloid-associated depression: a prodromal depression of Alzheimer disease?

1 reference

12 December 2020

Stress and glucocorticoid footprints in the brain-the path from depression to Alzheimer's disease

1 reference

12 December 2020

Glucocorticoids trigger Alzheimer disease-like pathobiochemistry in rat neuronal cells expressing human tau.

1 reference

12 December 2020

CSF biomarkers in relationship to cognitive profiles in Alzheimer disease

1 reference

12 December 2020

Hippocampal tau pathology is related to neuroanatomical connections: an ageing population-based study

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12 December 2020

Effects of stress throughout the lifespan on the brain, behaviour and cognition

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12 December 2020

Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain.

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12 December 2020

Epigenetic regulation in the pathophysiology of Alzheimer's disease

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12 December 2020

Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine

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12 December 2020

Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

1 reference

12 December 2020

Aggregation of detergent-insoluble tau is involved in neuronal loss but not in synaptic loss

1 reference

12 December 2020

Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration

1 reference

12 December 2020

Tau protein is required for amyloid {beta}-induced impairment of hippocampal long-term potentiation.

1 reference

12 December 2020

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

1 reference

12 December 2020

beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding.

1 reference

12 December 2020

Dephosphorylation of Alzheimer paired helical filaments by protein phosphatase-2A and -2B.

1 reference

12 December 2020

Stress exacerbates neuron loss and cytoskeletal pathology in the hippocampus

1 reference

12 December 2020

Sequential changes of tau-site-specific phosphorylation during development of paired helical filaments

1 reference

12 December 2020

Observation of metastable Abeta amyloid protofibrils by atomic force microscopy

1 reference

12 December 2020

Twenty-four hour cortisol release profiles in patients with Alzheimer's and Parkinson's disease compared to normal controls: ultradian secretory pulsatility and diurnal variation.

1 reference

12 December 2020

Cortisol secretion and Alzheimer's disease progression.

1 reference

12 December 2020

Cognitive and noncognitive symptoms in dementia patients: relationship to cortisol and dehydroepiandrosterone.

1 reference

12 December 2020

Phosphorylation of tau at both Thr 231 and Ser 262 is required for maximal inhibition of its binding to microtubules

1 reference

12 December 2020

Activation of tau protein kinase I/glycogen synthase kinase-3beta by amyloid beta peptide (25-35) enhances phosphorylation of tau in hippocampal neurons

1 reference

12 December 2020

10.1523/JNEUROSCI.0730-11.2011

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633145&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633145&resulttype=core&format=json

15 May 2020

1 reference