(Q53322022)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21905118%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

Inhibition of α-synuclein aggregation by small heat shock proteins (English)

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12 February 2020

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7

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12 February 2020

author name string

Ilona B Bruinsma

1

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12 February 2020

Kim A Bruggink

2

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12 February 2020

Karsten Kinast

3

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12 February 2020

Alexandra A M Versleijen

4

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12 February 2020

Ine M J Segers-Nolten

5

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12 February 2020

Vinod Subramaniam

6

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12 February 2020

Wilbert Boelens

8

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12 February 2020

Robert M W de Waal

9

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12 February 2020

Marcel M Verbeek

10

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12 February 2020

language of work or name

English

0 references

publication date

26 August 2011

1 reference

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12 February 2020

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12 February 2020

volume

79

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12 February 2020

issue

10

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12 February 2020

page(s)

2956-2967

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Neuropathological spectrum of synucleinopathies

12 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Alpha-synuclein in Lewy bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

A Drosophila model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Small heat shock proteins protect against alpha-synuclein-induced toxicity and aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Formation of toxic oligomeric alpha-synuclein species in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

CHIP targets toxic alpha-Synuclein oligomers for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Fibril fragmentation enhances amyloid cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Fibril fragmentation in amyloid assembly and cytotoxicity: when size matters

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

The impact of the E46K mutation on the properties of alpha-synuclein in its monomeric and oligomeric states.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Effect of familial Parkinson's disease point mutations A30P and A53T on the structural properties, aggregation, and fibrillation of human alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Crystallin proteins and amyloid fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

TorsinA and heat shock proteins act as molecular chaperones: suppression of alpha-synuclein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Small heat shock proteins: molecular structure and chaperone function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

The human genome encodes 10 alpha-crystallin-related small heat shock proteins: HspB1-10

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Ballooned neurons in several neurodegenerative diseases and stroke contain alpha B crystallin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

alpha B crystallin expression in non-lenticular tissues and selective presence in ubiquitinated inclusion bodies in human disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Muscle develops a specific form of small heat shock protein complex composed of MKBP/HSPB2 and HSPB3 during myogenic differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Small heat shock protein HspB8: its distribution in Alzheimer's disease brains and its inhibition of amyloid-beta protein aggregation and cerebrovascular amyloid-beta toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Specific association of small heat shock proteins with the pathological hallmarks of Alzheimer's disease brains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Interaction of the molecular chaperone alphaB-crystallin with alpha-synuclein: effects on amyloid fibril formation and chaperone activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

The interaction of alphaB-crystallin with mature alpha-synuclein amyloid fibrils inhibits their elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Small heat shock proteins inhibit amyloid-beta protein aggregation and cerebrovascular amyloid-beta protein toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Dependence of alpha-synuclein aggregate morphology on solution conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Quantitative morphological analysis reveals ultrastructural diversity of amyloid fibrils from alpha-synuclein mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

alpha-synuclein fibrillogenesis is nucleation-dependent. Implications for the pathogenesis of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Heat shock protein 27 phosphorylation: kinases, phosphatases, functions and pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Mimicking phosphorylation of alphaB-crystallin affects its chaperone activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

The molecular chaperone alpha-crystallin is in kinetic competition with aggregation to stabilize a monomeric molten-globule form of alpha-lactalbumin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

HspB8, a small heat shock protein mutated in human neuromuscular disorders, has in vivo chaperone activity in cultured cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Peptide aggregation in neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

The physical basis of how prion conformations determine strain phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

An analytical solution to the kinetics of breakable filament assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Monitoring the prevention of amyloid fibril formation by alpha-crystallin. Temperature dependence and the nature of the aggregating species

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Polydispersity of a mammalian chaperone: mass spectrometry reveals the population of oligomers in alphaB-crystallin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Structural insights on physiological functions and pathological effects of alpha-synuclein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Structural classification of toxic amyloid oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

Characterization of two novel human small heat shock proteins: protein kinase-related HspB8 and testis-specific HspB9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.23152

21 January 2018

Identifiers

DOI

10.1002/PROT.23152

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21905118%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference